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环氧化物

环氧化物是一类在碳链上含有一个环氧基团(即C-O-C三元环)的化合物。它们通常表示为R1-R2-OC-O-R3,其中R1、R2和R3可以是相同或不同的取代基。环氧化物广泛存在于自然界中,并且在有机化学、化学化工及生物医药领域中有着重要的应用。

环氧基团

环氧基团的结构式为O=C-O-C=O,它具有高度反应性,能够参与多种类型的反应,例如加成反应、开环反应等。由于其特殊的化学性质,环氧化物可以被用作有机合成中的重要中间体,也可以作为聚合物化学中制备交联剂的基础。

应用领域
  1. 医药与生物科学:一些天然存在的环氧化合物如环氧树脂(epoxides)具有抗癌、抗炎等活性。通过结构改造和修饰可以开发出新型的药物分子。
  2. 材料科学:环氧化合物在聚合物化学中非常重要,常被用作合成热固性树脂的重要成分,这些树脂广泛用于涂料、粘合剂等领域。
  3. 精细化工:环氧化物是许多精细化学品制备的关键中间体。通过与各种化合物进行开环或加成反应可合成多种有价值的化学品。
合成方法

环氧化物的合成方法多样,包括但不限于:

  • 氧化还原反应
  • 亲核加成反应(如使用过氧化氢)
  • 光化学反应

这些方法可根据具体需求选择最合适的合成路径。

中文名称 英文名称 CAS号 化学式 结构式图片
—— (2S)-2-[2-[2-[(2R)-oxiran-2-yl]ethoxy]ethyl]oxirane —— C8H14O3
(2S)-2-[2-[2-[(2R)-oxiran-2-yl]ethoxy]ethyl]oxirane
—— (2R)-2-[5-[(2S)-oxiran-2-yl]pentyl]oxirane —— C9H16O2
(2R)-2-[5-[(2S)-oxiran-2-yl]pentyl]oxirane
—— (1S,3R)-1-cyclohexyl-2,14-dioxatetraspiro[2.1.2.0.49.18.25.23]octadeca-10,12,17-triene —— C22H28O2
(1S,3R)-1-cyclohexyl-2,14-dioxatetraspiro[2.1.2.0.49.18.25.23]octadeca-10,12,17-triene
—— (1R,3S)-1-cyclohexyl-2,14-dioxatetraspiro[2.1.2.0.49.18.25.23]octadeca-10,12,17-triene —— C22H28O2
(1R,3S)-1-cyclohexyl-2,14-dioxatetraspiro[2.1.2.0.49.18.25.23]octadeca-10,12,17-triene
—— (1S,3S)-1-cyclohexyl-2,14-dioxatetraspiro[2.1.2.0.49.18.25.23]octadeca-10,12,17-triene —— C22H28O2
(1S,3S)-1-cyclohexyl-2,14-dioxatetraspiro[2.1.2.0.49.18.25.23]octadeca-10,12,17-triene
—— 3-methylbutyl (2R,3R)-3-methyl-3-phenyloxirane-2-carboxylate —— C15H20O3
3-methylbutyl (2R,3R)-3-methyl-3-phenyloxirane-2-carboxylate
—— hexyl (2S,3S)-2-methyl-3-phenyloxirane-2-carboxylate —— C16H22O3
hexyl (2S,3S)-2-methyl-3-phenyloxirane-2-carboxylate
—— pentyl (2R,3R)-3-ethyl-3-phenyloxirane-2-carboxylate —— C16H22O3
pentyl (2R,3R)-3-ethyl-3-phenyloxirane-2-carboxylate
—— 3-methylbutyl (2R,3R)-3-ethyl-3-phenyloxirane-2-carboxylate —— C16H22O3
3-methylbutyl (2R,3R)-3-ethyl-3-phenyloxirane-2-carboxylate
—— pentyl (2S,3R)-3-ethyl-3-phenyloxirane-2-carboxylate —— C16H22O3
pentyl (2S,3R)-3-ethyl-3-phenyloxirane-2-carboxylate
—— 2-butoxyethyl (2S,3R)-3-methyl-3-phenyloxirane-2-carboxylate —— C16H22O4
2-butoxyethyl (2S,3R)-3-methyl-3-phenyloxirane-2-carboxylate
—— hexyl (2S,3R)-2-methyl-3-phenyloxirane-2-carboxylate —— C16H22O3
hexyl (2S,3R)-2-methyl-3-phenyloxirane-2-carboxylate
—— butyl (2R,3S)-2-methyl-3-phenyloxirane-2-carboxylate —— C14H18O3
butyl (2R,3S)-2-methyl-3-phenyloxirane-2-carboxylate
—— pentyl (2S,3S)-2-methyl-3-phenyloxirane-2-carboxylate —— C15H20O3
pentyl (2S,3S)-2-methyl-3-phenyloxirane-2-carboxylate
—— pentyl (2R,3R)-2-methyl-3-phenyloxirane-2-carboxylate —— C15H20O3
pentyl (2R,3R)-2-methyl-3-phenyloxirane-2-carboxylate
—— hexyl (2R,3S)-3-methyl-3-phenyloxirane-2-carboxylate —— C16H22O3
hexyl (2R,3S)-3-methyl-3-phenyloxirane-2-carboxylate
—— 3-methylbutyl (2R,3S)-2-methyl-3-phenyloxirane-2-carboxylate —— C15H20O3
3-methylbutyl (2R,3S)-2-methyl-3-phenyloxirane-2-carboxylate
—— 3-methylbutyl (2S,3R)-3-methyl-3-phenyloxirane-2-carboxylate —— C15H20O3
3-methylbutyl (2S,3R)-3-methyl-3-phenyloxirane-2-carboxylate
—— 2-methylpropyl (2S,3R)-3-ethyl-3-phenyloxirane-2-carboxylate —— C15H20O3
2-methylpropyl (2S,3R)-3-ethyl-3-phenyloxirane-2-carboxylate
—— 3-methylbutyl (2S,3S)-2-methyl-3-phenyloxirane-2-carboxylate —— C15H20O3
3-methylbutyl (2S,3S)-2-methyl-3-phenyloxirane-2-carboxylate
—— butyl (2R,3S)-3-ethyl-3-phenyloxirane-2-carboxylate —— C15H20O3
butyl (2R,3S)-3-ethyl-3-phenyloxirane-2-carboxylate
—— butyl (2S,3S)-2-methyl-3-phenyloxirane-2-carboxylate —— C14H18O3
butyl (2S,3S)-2-methyl-3-phenyloxirane-2-carboxylate
—— 2-butoxyethyl (2S,3S)-3-methyl-3-phenyloxirane-2-carboxylate —— C16H22O4
2-butoxyethyl (2S,3S)-3-methyl-3-phenyloxirane-2-carboxylate
—— butyl (2S,3R)-3-ethyl-3-phenyloxirane-2-carboxylate —— C15H20O3
butyl (2S,3R)-3-ethyl-3-phenyloxirane-2-carboxylate
—— hexyl (2S,3R)-3-methyl-3-phenyloxirane-2-carboxylate —— C16H22O3
hexyl (2S,3R)-3-methyl-3-phenyloxirane-2-carboxylate
—— (2R,3S)-3-Phenyl-oxirane-2-carboxylic acid butyl ester —— C13H16O3
(2R,3S)-3-Phenyl-oxirane-2-carboxylic acid butyl ester
—— 2-butoxyethyl (2R,3R)-3-methyl-3-phenyloxirane-2-carboxylate —— C16H22O4
2-butoxyethyl (2R,3R)-3-methyl-3-phenyloxirane-2-carboxylate
—— ethyl (2S)-6-tert-butyl-1-oxaspiro[2.5]octane-2-carboxylate —— C14H24O3
ethyl (2S)-6-tert-butyl-1-oxaspiro[2.5]octane-2-carboxylate
—— 3-methylbutyl (2R,3R)-2-methyl-3-phenyloxirane-2-carboxylate —— C15H20O3
3-methylbutyl (2R,3R)-2-methyl-3-phenyloxirane-2-carboxylate
—— pentyl (2R,3S)-2-methyl-3-phenyloxirane-2-carboxylate —— C15H20O3
pentyl (2R,3S)-2-methyl-3-phenyloxirane-2-carboxylate
—— 3-methylbutyl (2R,3S)-3-methyl-3-phenyloxirane-2-carboxylate —— C15H20O3
3-methylbutyl (2R,3S)-3-methyl-3-phenyloxirane-2-carboxylate
—— pentyl (2R,3S)-3-methyl-3-phenyloxirane-2-carboxylate —— C15H20O3
pentyl (2R,3S)-3-methyl-3-phenyloxirane-2-carboxylate
—— hexyl (2R,3S)-2-methyl-3-phenyloxirane-2-carboxylate —— C16H22O3
hexyl (2R,3S)-2-methyl-3-phenyloxirane-2-carboxylate
—— pentyl (2R,3S)-3-ethyl-3-phenyloxirane-2-carboxylate —— C16H22O3
pentyl (2R,3S)-3-ethyl-3-phenyloxirane-2-carboxylate
—— (2S,3S)-2-methyl-3-phenyloxirane-2-carboxylic acid —— C10H10O3
(2S,3S)-2-methyl-3-phenyloxirane-2-carboxylic acid
—— 2-methylpropyl (2R,3S)-3-ethyl-3-phenyloxirane-2-carboxylate —— C15H20O3
2-methylpropyl (2R,3S)-3-ethyl-3-phenyloxirane-2-carboxylate
—— 3-methylbutyl (2S,3R)-2-methyl-3-phenyloxirane-2-carboxylate —— C15H20O3
3-methylbutyl (2S,3R)-2-methyl-3-phenyloxirane-2-carboxylate
—— pentyl (2S,3S)-3-ethyl-3-phenyloxirane-2-carboxylate —— C16H22O3
pentyl (2S,3S)-3-ethyl-3-phenyloxirane-2-carboxylate
—— 3-methylbutyl (2S,3R)-3-ethyl-3-phenyloxirane-2-carboxylate —— C16H22O3
3-methylbutyl (2S,3R)-3-ethyl-3-phenyloxirane-2-carboxylate
—— butyl (2R,3R)-2-methyl-3-phenyloxirane-2-carboxylate —— C14H18O3
butyl (2R,3R)-2-methyl-3-phenyloxirane-2-carboxylate
—— hexyl (2S,3S)-3-methyl-3-phenyloxirane-2-carboxylate —— C16H22O3
hexyl (2S,3S)-3-methyl-3-phenyloxirane-2-carboxylate
—— 2-methylpropyl (2S,3S)-3-ethyl-3-phenyloxirane-2-carboxylate —— C15H20O3
2-methylpropyl (2S,3S)-3-ethyl-3-phenyloxirane-2-carboxylate
—— 3-methylbutyl (2R,3S)-3-ethyl-3-phenyloxirane-2-carboxylate —— C16H22O3
3-methylbutyl (2R,3S)-3-ethyl-3-phenyloxirane-2-carboxylate
—— pentyl (2S,3R)-2-methyl-3-phenyloxirane-2-carboxylate —— C15H20O3
pentyl (2S,3R)-2-methyl-3-phenyloxirane-2-carboxylate
—— ethyl (2R)-6-tert-butyl-1-oxaspiro[2.5]octane-2-carboxylate —— C14H24O3
ethyl (2R)-6-tert-butyl-1-oxaspiro[2.5]octane-2-carboxylate
—— butyl (2R,3R)-3-ethyl-3-phenyloxirane-2-carboxylate —— C15H20O3
butyl (2R,3R)-3-ethyl-3-phenyloxirane-2-carboxylate
—— 2-methylpropyl (2R,3R)-3-ethyl-3-phenyloxirane-2-carboxylate —— C15H20O3
2-methylpropyl (2R,3R)-3-ethyl-3-phenyloxirane-2-carboxylate
—— butyl (2S,3S)-3-phenyloxirane-2-carboxylate —— C13H16O3
butyl (2S,3S)-3-phenyloxirane-2-carboxylate
—— 3-methylbutyl (2S,3S)-3-methyl-3-phenyloxirane-2-carboxylate —— C15H20O3
3-methylbutyl (2S,3S)-3-methyl-3-phenyloxirane-2-carboxylate
—— butyl (2S,3S)-3-ethyl-3-phenyloxirane-2-carboxylate —— C15H20O3
butyl (2S,3S)-3-ethyl-3-phenyloxirane-2-carboxylate