嘧啶类化合物
嘧啶类化合物是一类分子结构中含有两个氮原子的六元杂环化合物，与哒嗪和吡嗪互为同分异构体。由于其分子中存在共轭双键，表现出独特的紫外光谱特性。这类化合物易溶于水，碱性较弱，并且不易发生亲电取代反应；仅在5-位可以进行溴化反应，而不具备硝化或磺化的能力，但容易经历亲核取代反应。
嘧啶及其衍生物广泛存在于自然界中，如磺胺嘧啶、巴比妥酸以及维生素B1等。在核酸分子内，有三种重要的嘧啶类碱基：尿嘧啶、胸腺嘧啶和胞嘧啶；其中，在DNA中主要包含胞嘧啶与胸腺嘧啶，而在RNA中则主要含有胞嘧啶及尿嘧啶，并且在某些特定的核酸中还可能发现少量的嘧啶修饰碱基。此外，许多药物分子如磺胺嘧啶、甲氧苄氨嘧啶和6-巯基嘌呤等都含有嘧啶环。
作为重要的医药原料，嘧啶及其衍生物被用于生产多种药物，例如维生素B1、磺胺嘧啶、磺胺异二甲嘧啶及磺胺间二甲氧嘧啶等。同时，它们也是农药的重要组成部分，包括二嗪农、嘧啶醇、灭瘟素、除草定、喃啶草、鼠立死、环菌灵、甲菌定、乙菌定、磺嘧菌灵、比嗪农、抗蚜威、乙基虫螨磷、虫螨磷、多氧霉素等。此外，作为染料的原料，具有三卤化嘧啶核结构的化合物因其与纤维之间的良好反应性，已成为一种备受关注的反应染料。
| 中文名称 | 英文名称 | CAS号 | 化学式 | 结构式图片 |
|---|---|---|---|---|
| 5-溴嘧啶-2-羧酸 | 5-bromo-2-pyrimidinecarboxylic acid | 37131-87-6 | C5H3BrN2O2 |
|
| 5-溴嘧啶-2-羧酰胺 | 5-Brom-pyrimidin-2-carbonsaeure-amid | 38275-60-4 | C5H4BrN3O |
|
| 5-溴嘧啶-2-甲醛 | 5-bromopyrimidine-2-carbaldehyde | 944902-05-0 | C5H3BrN2O |
|
| 5-溴嘧啶 1-氧化物 | 5-bromopyrimidine N-oxide | 36529-69-8 | C4H3BrN2O |
|
| 5-溴嘧啶 | 5-bromo-pyrimidine | 4595-59-9 | C4H3BrN2 |
|
| 5-溴吡唑并[1,5-a]嘧啶 | 5-bromopyrazolo[1,5-a]pyrimidine | 1159981-95-9 | C6H4BrN3 |
|
| 5-溴-n-环丁基-2-嘧啶胺 | 5-bromo-2-(cyclobutylamino)-pyrimidine | 947534-33-0 | C8H10BrN3 |
|
| 5-溴-N-甲基嘧啶-4-胺 | 5-Brom-4-(N-methylamino)pyrimidin | 56181-38-5 | C5H6BrN3 |
|
| 5-溴-N-(2-甲氧基乙基)嘧啶-2-胺 | 5-bromo-N-(2-methoxyethyl)pyrimidin-2-amine | 886365-79-3 | C7H10BrN3O |
|
| 5-溴-7H-吡咯并[2,3-d]嘧啶-4-甲腈 | 5-bromo-7H-pyrrolo[2,3-d]pyrimidine-4-carbonitrile | 1168106-92-0 | C7H3BrN4 |
|
| 5-溴-7H-吡咯并[2,3-d]嘧啶 | 5-bromo-7H-pyrrolo[2,3-d]pyrimidine | 175791-49-8 | C6H4BrN3 |
|
| 5-溴-7-甲基-7h-吡咯并[2,3-d]嘧啶-4-胺 | 5-bromo-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine | 1337532-51-0 | C7H7BrN4 |
|
| 5-溴-6-羟基嘧啶-4-羧酸 | 5-bromo-6-oxo-1,6-dihydro-pyrimidine-4-carboxylic acid | 135274-82-7 | C5H3BrN2O3 |
|
| 5-溴-6-甲基尿嘧啶 | 5-bromo-6-methyluracil | 15018-56-1 | C5H5BrN2O2 |
|
| 5-溴-6-甲基嘧啶-4-醇 | 5-Brom-4-hydroxy-6-methyl-pyrimidin | 3438-52-6 | C5H5BrN2O |
|
| 5-溴-6-氯-2-(甲基硫代)嘧啶-4-胺 | 5-bromo-6-chloro-2-(methylthio)pyrimidine-4-amine | 63931-22-6 | C5H5BrClN3S |
|
| 5-溴-6-氯-2,4-嘧啶二胺 | 2,4-diamino-5-bromo-6-chloropyrimidine | 7150-68-7 | C4H4BrClN4 |
|
| 5-溴-6-氮尿嘧啶 | 6-bromo-1,2,4-triazine-3,5(2H,4H)-dione | 4956-05-2 | C3H2BrN3O2 |
|
| 5-溴-6-氨基尿嘧啶 | 6-amino-5-bromo-2,4(1H,3H)-pyrimidinedione | 6312-73-8 | C4H4BrN3O2 |
|
| 5-溴-4-苯基嘧啶 | 5-bromo-4-phenylpyrimidine | 3543-46-2 | C10H7BrN2 |
|
| 5-溴-4-碘嘧啶 | 5-bromo-4-iodopyrimidine | 898559-22-3 | C4H2BrIN2 |
|
| 5-溴-4-甲基嘧啶 | 5-bromo-4-methylpyrimidine | 1439-09-4 | C5H5BrN2 |
|
| 5-溴-4-环己基嘧啶 | 5-bromo-4-cyclohexylpyrimidine | 941294-28-6 | C10H13BrN2 |
|
| 5-溴-4-环丙基嘧啶 | 5-Bromo-4-cyclopentylpyrimidine | 951884-32-5 | C9H11BrN2 |
|
| 5-溴-4-氯噻吩并[2,3-d]嘧啶 | 5-bromo-4-chlorothieno[2,3-d]pyrimidine | 814918-95-1 | C6H2BrClN2S |
|
| 5-溴-4-氯嘧啶-2-胺 | 5-bromo-4-chloropyrimidin-2-amine | 1044767-99-8 | C4H3BrClN3 |
|
| 5-溴-4-氯-7H-吡咯并[2,3-d]嘧啶 | 5-bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine | 22276-95-5 | C6H3BrClN3 |
|
| 5-溴-4-氯-7-甲基-7h-吡咯并[2,3-d]嘧啶 | 5-bromo-4-chloro-7-methyl-7H-pyrrolo[2,3-d]pyrimidine | 1266343-30-9 | C7H5BrClN3 |
|
| 5-溴-4-氯-6-甲基嘧啶 | 5-bromo-4-chloro-6-methylpyrimidine | 3438-55-9 | C5H4BrClN2 |
|
| 5-溴-4-氯-6-甲基-2-嘧啶胺 | 5-bromo-4-chloro-6-methylpyrimidin-2-amine | 6314-12-1 | C5H5BrClN3 |
|
| 5-溴-4-氯-6-三氟甲基嘧啶 | 5-bromo-4-chloro-6-(trifluoromethyl)pyrimidine | 425392-76-3 | C5HBrClF3N2 |
|
| 5-溴-4-氯-2-甲基嘧啶 | 5-bromo-4-chloro-2-methylpyrimidine | 861383-73-5 | C5H4BrClN2 |
|
| 5-溴-4-戊基嘧啶 | 5-Bromo-4-pentylpyrimidine | 951884-34-7 | C9H13BrN2 |
|
| 5-溴-4-异辛基嘧啶 | 5-Bromo-4-(6-methylheptyl)pyrimidine | 951884-24-5 | C12H19BrN2 |
|
| 5-溴-4-异戊基嘧啶 | 5-Bromo-4-isopentylpyrimidine | 951884-42-7 | C9H13BrN2 |
|
| 5-溴-4-异丙基嘧啶 | 5-bromo-4-isopropylpyrimidine | 951884-28-9 | C7H9BrN2 |
|
| 5-溴-4-庚基嘧啶 | 5-Bromo-4-heptylpyrimidine | 951884-44-9 | C11H17BrN2 |
|
| 5-溴-4-己基嘧啶 | 5-Bromo-4-hexylpyrimidine | 951884-38-1 | C10H15BrN2 |
|
| 5-溴-4-嘧啶甲醛 | 5-bromopyrimidine-4-carbaldehyde | 933746-26-0 | C5H3BrN2O |
|
| 5-溴-4-嘧啶甲酸甲酯 | methyl 5-bromopyrimidine-4-carboxylate | 1009826-93-0 | C6H5BrN2O2 |
|
| 5-溴-4-嘧啶甲酸 | 5-bromopyrimidine-4-carboxylic acid | 64224-60-8 | C5H3BrN2O2 |
|
| 5-溴-4-嘧啶乙酸 | 2-(5-Bromopyrimidin-4-yl)acetic acid | 933721-19-8 | C6H5BrN2O2 |
|
| 5-溴-4-乙基嘧啶 | 5-bromo-4-ethylpyrimidine | 951884-36-9 | C6H7BrN2 |
|
| 5-溴-4-丙基嘧啶 | 5-Bromo-4-propylpyrimidine | 951884-26-7 | C7H9BrN2 |
|
| 5-溴-4-丁基嘧啶 | 5-Bromo-4-butylpyrimidine | 4595-64-6 | C8H11BrN2 |
|
| 5-溴-4-P-甲苯基嘧啶 | 5-bromo-4-(p-tolyl)pyrimidine | 149323-50-2 | C11H9BrN2 |
|
| 5-溴-4-O-甲苯基嘧啶 | 5-Bromo-4-o-tolylpyrimidine | 941294-34-4 | C11H9BrN2 |
|
| 5-溴-4-(噻吩-2-基)嘧啶 | 5-bromo-4-(thiophen-2-yl)pyrimidine | 5162-74-3 | C8H5BrN2S |
|
| 5-溴-4-(仲丁基)嘧啶 | 5-Bromo-4-sec-butylpyrimidine | 951884-30-3 | C8H11BrN2 |
|
| 5-溴-4-(4-甲氧基苯基)嘧啶 | 5-bromo-4-(4-methoxyphenyl)pyrimidine | 941294-41-3 | C11H9BrN2O |
|
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