2'-deoxy-3',5'-bis(O-tert-butyldimethylsilyl)-5-iodouridine | 148134-86-5

分子结构分类

有机化合物 - 核苷、核苷酸和类似物 - 嘧啶核苷

中文名称

——

中文别名

——

英文名称

2'-deoxy-3',5'-bis(O-tert-butyldimethylsilyl)-5-iodouridine

英文别名

5-iodo-2'-deoxyuridine 3',5'-di-tert-butyldimethyl silyl ether；3',5'-bis-(O-tert-butyldimethylsilyl)-5-iodo-2'-deoxyuridine；3',5'-di-O-tert-butyldimethylsilyl-5-iodo-2'-deoxyuridine；1-[(2R,4S,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-[[tert-butyl(dimethyl)silyl]oxymethyl]oxolan-2-yl]-5-iodopyrimidine-2,4-dione

2'-deoxy-3',5'-bis(O-tert-butyldimethylsilyl)-5-iodouridine化学式

CAS

148134-86-5

化学式

C₂₁H₃₉IN₂O₅Si₂

mdl

——

分子量

582.627

InChiKey

XCSVWKREMARNHH-GVDBMIGSSA-N

BEILSTEIN

——

EINECS

——

物化性质

密度：

1.29±0.1 g/cm3(Predicted)

计算性质

辛醇/水分配系数(LogP)：

4.84
重原子数：

31
可旋转键数：

8
环数：

2.0
sp3杂化的碳原子比例：

0.81
拓扑面积：

77.1
氢给体数：

1
氢受体数：

5

上下游信息

上游原料

中文名称	英文名称	CAS号	化学式	分子量
碘苷	5-Iodo-2'-deoxyuridine	54-42-2	C₉H₁₁IN₂O₅	354.101

下游产品

中文名称	英文名称	CAS号	化学式	分子量
——	3'-O-(tert-butyldimethylsilyl)-5-iodo-2'-deoxyuridine	159140-63-3	C₁₅H₂₅IN₂O₅Si	468.364
——	3',5'-O-di(tert-butyldimethylsilyl)-2'-deoxyuridine	64911-18-8	C₂₁H₄₀N₂O₅Si₂	456.73
——	3',5'-di-O-tert-butyldimethylsilyl-2'-deoxy-5-deuterouridine	124667-78-3	C₂₁H₄₀N₂O₅Si₂	457.722
3,5-双-o-(t-丁基二甲基甲硅烷基)胸腺嘧啶脱氧核苷	3',5'-O-di(tert-butyldimethylsilyl)thymidine	40733-26-4	C₂₂H₄₂N₂O₅Si₂	470.757
——	2'-deoxy-3',5'-bis(O-tert-butyldimethylsilyl)-5-ethynyluridine	924890-35-7	C₂₃H₄₀N₂O₅Si₂	480.752
——	3',5'-bis(O-tert-butyldimethylsilyl)-5-hydroxymethyl-2'-deoxyuridine	354581-59-2	C₂₂H₄₂N₂O₆Si₂	486.756
——	3',5'-bis-(O-tert-butyldimethylsilyl)-5-vinyl-2'-deoxyuridine	148134-87-6	C₂₃H₄₂N₂O₅Si₂	482.768
——	3',5'-bis-(O-tert-butyldimethylsilyl)-5-formyl-2'-deoxyuridine	142667-68-3	C₂₂H₄₀N₂O₆Si₂	484.74
——	1-[(2R,4S,5R)-4-(tert-Butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-5-(3-hydroxy-propyl)-1H-pyrimidine-2,4-dione	151867-59-3	C₂₄H₄₆N₂O₆Si₂	514.81
——	3',5'-bis-O-(tert-butyldimethylsilyl)-C5-(4-hydroxybutyl)-2'-deoxyuridine	151867-60-6	C₂₅H₄₈N₂O₆Si₂	528.837
——	5-(3-hydroxypropyn-1-yl)-2'-deoxyuridine 3',5'-di-tert-butyldimethylsilyl ether	151867-56-0	C₂₄H₄₂N₂O₆Si₂	510.778
——	3',5'-bis-O-(tert-butyldimethylsilyl)-5-(5-hydroxypent-1-ynyl)-2'-deoxyuridine	878197-59-2	C₂₆H₄₆N₂O₆Si₂	538.832
——	3',5'-bis-O-(tert-butyldimethylsilyl)-C5-(4-hydroxy-1-butynyl)-2'-deoxyuridine	151867-57-1	C₂₅H₄₄N₂O₆Si₂	524.805
——	5-{1-[(2R,4S,5R)-4-(tert-Butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-2,4-dioxo-1,2,3,4-tetrahydro-pyrimidin-5-yl}-pent-4-ynal	878197-60-5	C₂₆H₄₄N₂O₆Si₂	536.816
——	3',5'-O-bis(tert-butyldimethylsilyl)-2'-deoxy-5-(6-hydroxyhex-1-ynyl)uridine	220643-38-9	C₂₇H₄₈N₂O₆Si₂	552.859
——	5-(trideuteromethyl)-3′,5′-(tert-butyl-dimethylsilyl)-2′-deoxyuridine	1280736-10-8	C₂₂H₄₂N₂O₅Si₂	473.733
——	5-(6-Amino-hex-1-ynyl)-1-[(2R,4S,5R)-4-(tert-butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-1H-pyrimidine-2,4-dione	220643-41-4	C₂₇H₄₉N₃O₅Si₂	551.874
——	3',5'-bis-O-(tert-butyldimethylsilyl)-5-[12-hydroxy-(4,7,10-trioxadodec-1-ynyl)]-2'-deoxyuridine	951659-60-2	C₃₀H₅₄N₂O₉Si₂	642.938
——	6-[1-[(2R,4S,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-[[tert-butyl(dimethyl)silyl]oxymethyl]oxolan-2-yl]-2,4-dioxopyrimidin-5-yl]hex-5-ynoic acid	220643-46-9	C₂₇H₄₆N₂O₇Si₂	566.842
——	1-((2R,4S,5R)-4-((tert-butyldimethylsilyl)oxy)-5-(((tert-butyldimethylsilyl)oxy)methyl)tetrahydrofuran-2-yl)-5-(8-(trimethylsilyl)octa-1,7-diyn-1-yl)pyrimidine-2,4(1H,3H)-dione	1021300-92-4	C₃₂H₅₆N₂O₅Si₃	633.064
——	3',5'-bis-O-(tert-butyldimethylsilyl)-5-(5-azidopent-1-ynyl)-2'-deoxyuridine	951659-61-3	C₂₆H₄₅N₅O₅Si₂	563.845
——	5-(6-azidohex-1-ynyl)-1-[(2R,4S,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-[[tert-butyl(dimethyl)silyl]oxymethyl]oxolan-2-yl]pyrimidine-2,4-dione	220643-40-3	C₂₇H₄₇N₅O₅Si₂	577.872
——	3',5'-di-O-tert-butyldimethylsilyl-2'-deoxy-5-phenyltelluro-uridine	1256466-64-4	C₂₇H₄₄N₂O₅Si₂Te	660.428
——	6-[1-[(2R,4S,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-[[tert-butyl(dimethyl)silyl]oxymethyl]oxolan-2-yl]-2,4-dioxopyrimidin-5-yl]hex-5-ynyl methanesulfonate	220643-39-0	C₂₈H₅₀N₂O₈SSi₂	630.951
——	3',5'-bis-(O-tert-butyldimethylsilyl)-5-(1,2-dihydroxyethyl)-2'-deoxyuridine	186086-42-0	C₂₃H₄₄N₂O₇Si₂	516.783
——	3',5'-bis-(dimethyl-tert-butylsilyl)-5-(3-(2-(dimethylamino)ethoxy)-3-methylbutyn-1-yl)-2'-deoxyuridine	1449476-48-5	C₃₀H₅₅N₃O₆Si₂	609.954
——	3',5'-bis-tert-butyldimethylsilyl-5-propenoyl-2'-deoxyuridine	157022-74-7	C₂₄H₄₂N₂O₆Si₂	510.778
——	1-[(2R,4S,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-[[tert-butyl(dimethyl)silyl]oxymethyl]oxolan-2-yl]-5-[tert-butyl(hydroxy)amino]pyrimidine-2,4-dione	519056-33-8	C₂₅H₄₉N₃O₆Si₂	543.852
——	5',3'-bis-O-tert-butyldimethylsilyl-5-[2-(4-N,N-dimethylaminophenyl)ethynyl]-2'-deoxyuridine	289481-37-4	C₃₁H₄₉N₃O₅Si₂	599.918
——	3',5'-di-O-tert-butyldimethylsilyl-5-ethoxycarbonyl-2'-deoxyuridine	1210427-47-6	C₂₄H₄₄N₂O₇Si₂	528.794
——	N-[2-[3-[1-[(2R,4S,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-[[tert-butyl(dimethyl)silyl]oxymethyl]oxolan-2-yl]-2,4-dioxopyrimidin-5-yl]propyl-(2,2,2-trifluoroacetyl)amino]ethyl]-2,2,2-trifluoroacetamide	247096-84-0	C₃₀H₅₀F₆N₄O₇Si₂	748.911
——	5-(3-benzoylthiopropyn-1-yl)-2'-deoxyuridine 3',5'-di-tert-butyldimethylsilyl ether	172531-41-8	C₃₁H₄₆N₂O₆SSi₂	630.953
——	Thiobenzoic acid S-(4-{1-[(2R,4S,5R)-4-(tert-butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-2,4-dioxo-1,2,3,4-tetrahydro-pyrimidin-5-yl}-butyl) ester	187245-18-7	C₃₂H₅₂N₂O₆SSi₂