生化试剂
生化试剂（Biochemical reagent）是指用于生命科学研究的生物材料或有机化合物，以及临床诊断和医学研究所需的各类试剂。它们是从生物体中提取或通过化学合成得到的基本成分，主要用于生物成分的分析鉴定及生物制品的制造。
随着生命科学的发展，生化试剂已成长为一种重要的化学试剂类别，品种繁多，达10000多种。中国市场上销售的生化试剂有2500种。由于生化试剂对温度、湿度和光照敏感，容易丧失活力且保存期较短，因此对其贮存与运输条件要求较高。例如，绝大多数酶试剂需在0～5℃下保存，而某些用于遗传工程研究的酶试剂则需要在-20℃下冷藏。
根据生物体组织中所含物质或代谢过程中产生的物质，生化试剂可以分为氨基酸、多肽、蛋白质、核苷酸、核酸、酶、辅酶、糖类、酯类和激素等。此外，按生物学研究的需求，它们还可细分为电泳试剂、色谱试剂、免疫试剂、标记试剂以及组织化学试剂等。
不同用途的生化试剂对纯度和技术要求各不相同。例如，酶试剂通常有粗制酶、结晶酶、多次结晶酶及不含特定杂酶的酶制剂等多种形式。生产生化试剂的方法主要有三种：从生物体中分离和提纯、化学合成以及发酵等。对于生化试剂产品的技术要求包括含量、熔点、冰点、旋光度、含水量、光谱特征、折光性、密度及生物活性等。
下级分类
| 中文名称 | 英文名称 | CAS号 | 化学式 | 结构式图片 |
|---|---|---|---|---|
| Boc-DL-(2-甲氧基苯基)甘氨酸 | 2-(tert-butoxycarbonylamino)-2-(2-methoxyphenyl)acetic acid | 179417-69-7 | C14H19NO5 |
|
| Boc-D-3-氰基苯丙氨酸 | Boc-D-3-cyanophenylalanine | 205445-56-3 | C15H18N2O4 |
|
| Boc-7-溴-DL-色氨酸 | Boc-7-bromo-DL-tryptophan | 1219432-58-2 | C16H19BrN2O4 |
|
| Boc-5-羟基-l-色胺 | (S)-2-((tert-butoxycarbonyl)amino)-3-(5-hydroxy-1H-indol-3-yl)propanoic acid | 119768-45-5 | C16H20N2O5 |
|
| Boc-4-氨基-3-甲基苯甲酸 | N-Boc-4-amino-3-methylbenzoic acid | 180976-94-7 | C13H17NO4 |
|
| Boc-2-氨基-6-氯苯甲酸 | 2-[(tert-butoxycarbonyl)amino]-6-chlorobenzoic acid | 616224-61-4 | C12H14ClNO4 |
|
| Boc-(4-氨基苯基)乙酸 | 2-(4-(tert-butoxycarbonylamino)phenyl)acetic acid | 81196-09-0 | C13H17NO4 |
|
| Boc-(2s,4r)-4-苄基-吡咯烷-2-羧酸 | (2S,4R)-4-benzyl-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylic acid | 153074-95-4 | C17H23NO4 |
|
| Boc-(2r,5s)-5-苯基-吡咯烷-2-羧酸 | (2R,5S)-N-butoxycarbonyl-5-phenyl-pyrrolidine-2-carboxylic acid | 158706-46-8 | C16H21NO4 |
|
| BTZ 043;2-[(2S)-2-甲基-1,4-二氧杂-8-氮杂螺[4.5]癸烷-8-基]-8-硝基-6-三氟甲基-4H-1,3-苯并噻嗪-4-酮 | 2-[(2S)-2-methyl-1,4-dioxa-8-azaspiro[4.5]dec-8-yl]-8-nitro-6-(trifluoromethyl)-4H-1,3-benzothiazin-4-one | 1161233-85-7 | C17H16F3N3O5S |
|
| BOC-RS-2-氨基辛二酸 | 2-(tert-butoxycarbonylamino)octanedioic acid | 292642-79-6 | C13H23NO6 |
|
| BOC-PEN(乙酰氨基硫代甲基)-OH | S-(Acetylaminomethyl)-N-(tert-butyloxycarbonyl)penicillamine | 129972-45-8 | C13H24N2O5S |
|
| BOC-L-环丙基丙氨酸-DCHA | (S)-2-((tert-butoxycarbonyl)amino)-3-cyclopropylpropanoic acid | 89483-06-7 | C11H19NO4 |
|
| BOC-DL-3-氨基乙酸 | 3-t-butoxycarbonylaminobutyric acid | 52815-19-7 | C9H17NO4 |
|
| BOC-DL-(2-甲基苯基)甘氨酸 | 2-(tert-butoxycarbonylamino)-2-(2-methylphenyl)acetic acid | 40512-48-9 | C14H19NO4 |
|
| BOC-D-7-羟基-1,2,3,4-四氢异喹啉-3-羧酸 | (3R)-2-(tert-butoxycarbonyl)-7-hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid | 214630-00-9 | C15H19NO5 |
|
| BOC-D-4-苄氧基酪氨醇 | (R)-[1-(4-benzyloxybenzyl)-2-hydroxyethyl]carbamic acid tert-butyl ester | 198470-63-2 | C21H27NO4 |
|
| BOC-D-2,3,4,5,6-五氟苯丙氨酸 | N-(tert-butoxycarbonyl)-2,3,4,5,6-pentafluoro-D-phenylalanine | 136207-26-6 | C14H14F5NO4 |
|
| BOC-ALPHA-甲基-L-苯丙氨酸 | (2R)-(-)-N-<(1,1-dimethylethyl)oxycarbonyl>-2-methyl-3-phenylalanine | 111771-58-5 | C15H21NO4 |
|
| BOC-5-甲氧基-L-色氨酸 | (S)-2-(tert-butoxycarbonylamino)-3-(5-methoxy-1H-indol-3-yl)propanoic acid | 114903-30-9 | C17H22N2O5 |
|
| BOC-5-氯-DL-色氨酸 | Boc-5-Cl-Trp-OH | 361576-61-6 | C16H19ClN2O4 |
|
| BOC-4-氨基苄醇 | tert-butyl N-[4-(hydroxymethyl)phenyl]carbamate | 144072-29-7 | C12H17NO3 |
|
| BOC-4-氨基-3-甲氧基苯甲酸 | N-Boc-4-amino-3-methoxybenzoic acid | 180976-98-1 | C13H17NO5 |
|
| BOC-3-氨基-4-甲基苯甲酸 | 3-((tert-butoxycarbonyl)amino)-4-methylbenzoic acid | 231958-04-6 | C13H17NO4 |
|
| BOC-3-氨基-4-氯苯甲酸 | 3-[(tert-butoxycarbonyl)amino]-4-chlorobenzoic acid | 160450-12-4 | C12H14ClNO4 |
|
| BOC-3,5-二碘-D-酪氨酸 | Boc-3,5-Diiodo-D-tyrosine | 214630-08-7 | C14H17I2NO5 |
|
| BOC-2-氨基苄醇 | 2-(tert-butyloxycarbonyl)aminobenzyl alcohol | 164226-32-8 | C12H17NO3 |
|
| BMS-687453抑制剂 | BMS-687453 | 1000998-59-3 | C22H21ClN2O6 |
|
| BIIB-024; 6-氨基-5-氯-N-[(1R)-1-[5-[[[5-氯-4-(三氟甲基)-2-吡啶基]氨基]羰基]-2-噻唑基]乙基]-4-嘧啶甲酰胺 | (R)-2-(1-(6-amino-5-chloropyrimidine-4-carboxamido)ethyl)-N-(5-chloro-4-(trifluoromethyl)pyridin-2-yl)thiazole-5-carboxamide | 1096708-71-2 | C17H12Cl2F3N7O2S |
|
| BI-847325,MEK和极光激酶(AK)的ATP竞争性双重抑制剂 | (Z)-3-(3-(((4-((dimethylamino)methyl)phenyl)amino)(phenyl)methylene)-2-oxoindolin-6-yl)-N-ethylpropiolamide | 1207293-36-4 | C29H28N4O2 |
|
| BHQ-1氨基 | BHQ-1 amine | 1308657-79-5 | C25H29N7O3 |
|
| BEZ235 对甲苯磺酸盐 | 2-methyl-2-[4-(3-methyl-2-oxo-8-quinolin-3-yl-2,3-dihydro-imidazo[4,5-c]quinolin-1-yl)-phenyl]-propionitrile monotosylate salt | 1028385-32-1 | C7H8O3S*C30H23N5O |
|
| BET溴区抑制剂(CPI-0610) | 2-((4S)-6-(4-chlorophenyl)-1-methyl-4H-benzo[c]isoxazolo[4,5-e]azepin-4-yl)acetamide | 1380087-89-7 | C20H16ClN3O2 |
|
| BENZIMIDAVIR苯并咪唑核苷 | maribavir | 176161-24-3 | C15H19Cl2N3O4 |
|
| BECHCL,一个竞争性的ARGINASEII抑制剂 | Loride | 222638-67-7 | C5H13BClNO4S |
|
| BD1047二氢溴酸盐 | BD 1047 Dihydrobromide | 138356-21-5 | C13H22Br2Cl2N2 |
|
| BAY 6755 | Bay 60-7550 | 439083-90-6 | C27H32N4O4 |
|
| BAY 61-366 | BAY 61-3606 dihydrochloride | 648903-57-5 | C20H20Cl2N6O3 |
|
| BATEFENTEROL游离态 | (R)-1-(3-((2-chloro-4-(((2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethyl)amino)methyl)-5-methoxyphenyl)amino)-3-oxopropyl) piperidin-4-yl[1,1'-biphenyl]-2-ylcarbamate | 743461-65-6 | C40H42ClN5O7 |
|
| Avl292苯磺酸盐 | N-(3-(5-fluoro-2-(4-(2-methoxyethoxy)phenylamino)pyrimidin-4-ylamino)phenyl)acrylamide besylate | 1360053-81-1 | C6H6O3S*C22H22FN5O3 |
|
| Avibactam; 硫酸单[(1R,2S,5R)-2-(氨基羰基)-7-氧代-1,6-氮杂双环[3.2.1]辛-6-基]酯 | avibactam | 1192500-31-4 | C7H11N3O6S |
|
| AZD9291中间体1 | N1-(2-dimethylaminoethyl)-5-methoxy-N1-methyl-N4-[4-(1-methylindol-3-yl)pyrimidin-2-yl]benzene-1,2,4-triamine | 1421372-66-8 | C25H31N7O |
|
| AZD 7687; [反式-4-[4-(6-氨基甲酰基-3,5-二甲基吡嗪-2-基)苯基]环己基]乙酸 | {trans-4-[4-(6-carbamoyl-3,5-dimethylpyrazin-2-yl)phenyl]cyclohexyl}acetic acid | 1166827-44-6 | C21H25N3O3 |
|
| AV-412; N-[4-[(3-氯-4-氟苯基)氨基]-7-[3-甲基-3-(4-甲基-1-哌嗪基)-1-丁炔-1-基]-6-喹唑啉基]-2-丙烯酰胺 | AV-412 | 451492-95-8 | C27H28ClFN6O |
|
| AT425-酸 | 4-[3-(ethoxycarbonyl)-7,8-dihydro-6,8,8-trimethyl-2-oxo-2H-pyrano[3,2-g]quinolin-9(6H)-yl]butanoic acid | 652966-03-5 | C22H27NO6 |
|
| AR-C 155858; (S)-6-[(3,5-二甲基-1H-吡唑-4-基)甲基]-5-[(4-羟基异噁唑烷-2-基)羰基]-1-异丁基-3-甲基噻吩并[2,3-d]嘧啶-2,4(1H,3H)-二酮 | AR-C155858 | 496791-37-8 | C21H27N5O5S |
|
| APILIMOD甲磺酸盐 | Apilimod mesylate | 870087-36-8 | C25H34N6O8S2 |
|
| ALPHA-(2-羧基乙基)-OMEGA-[2-[[(9H-芴-9-基甲氧基)羰基]氨基]乙氧基]-聚环氧乙烷 | Fmoc-9-amino-4,7-dioxanonanoic acid | 850312-72-0 | C22H25NO6 |
|
| ALDH2激动剂(ALDA-1) | (N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide) | 349438-38-6 | C15H11Cl2NO3 |
|
| AL 82D6 | AL082D06 | 256925-03-8 | C23H24ClN3O2 |
|
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