生化试剂
生化试剂（Biochemical reagent）是指用于生命科学研究的生物材料或有机化合物，以及临床诊断和医学研究所需的各类试剂。它们是从生物体中提取或通过化学合成得到的基本成分，主要用于生物成分的分析鉴定及生物制品的制造。
随着生命科学的发展，生化试剂已成长为一种重要的化学试剂类别，品种繁多，达10000多种。中国市场上销售的生化试剂有2500种。由于生化试剂对温度、湿度和光照敏感，容易丧失活力且保存期较短，因此对其贮存与运输条件要求较高。例如，绝大多数酶试剂需在0～5℃下保存，而某些用于遗传工程研究的酶试剂则需要在-20℃下冷藏。
根据生物体组织中所含物质或代谢过程中产生的物质，生化试剂可以分为氨基酸、多肽、蛋白质、核苷酸、核酸、酶、辅酶、糖类、酯类和激素等。此外，按生物学研究的需求，它们还可细分为电泳试剂、色谱试剂、免疫试剂、标记试剂以及组织化学试剂等。
不同用途的生化试剂对纯度和技术要求各不相同。例如，酶试剂通常有粗制酶、结晶酶、多次结晶酶及不含特定杂酶的酶制剂等多种形式。生产生化试剂的方法主要有三种：从生物体中分离和提纯、化学合成以及发酵等。对于生化试剂产品的技术要求包括含量、熔点、冰点、旋光度、含水量、光谱特征、折光性、密度及生物活性等。
下级分类
| 中文名称 | 英文名称 | CAS号 | 化学式 | 结构式图片 |
|---|---|---|---|---|
| 15-(Boc-氨基)-4,7,10,13-四氧杂十五烷酸 | 2,2-dimethyl-4-oxo-3,8,11,14,17-pentaoxa-5-azaicosan-20-oic acid | 756525-91-4 | C16H31NO8 |
|
| 10-氧壬二酸 | 10-oxononadecanedioic acid | 18197-46-1 | C19H34O5 |
|
| 10-乙酰基-3,7-二羟基吩嗪 | 10-acetyl-3,7-dihydroxyphenoxazine | 119171-73-2 | C14H11NO4 |
|
| 1-萘酚酞 | α-naphtholphthalein | 596-01-0 | C28H18O4 |
|
| 1-萘磷酸二钠水合物 | 1-Naphthalenol, dihydrogen phosphate, disodium salt | 2183-17-7 | C10H9Na2O4P |
|
| 1-萘基乙酰基精胺 | 1-Naphthylacetylspermine | 122306-11-0 | C22H34N4O |
|
| 1-苯基-2,3-二甲基-4-甲氨基吡唑啉-5-酮-N-甲基磺酸镁 | Bis(((2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino)methanesulphonato)magnesium | 63372-86-1 | C26H32MgN6O8S2 |
|
| 1-苄基胍盐酸盐 | 1-benzylguanidine hydrochloride | 1197-49-5 | C8H11N3*ClH |
|
| 1-肉豆蔻-sn-甘油-3-磷酸胆碱 | 1-myristoyl-2-hydroxy-sn-glycero-3-phosphocholine | 20559-16-4 | C22H46NO7P |
|
| 1-甲基-7-亚硝基尿酸酐 | 1-methyl-7-nitroisatoic anhydride | 73043-80-8 | C9H6N2O5 |
|
| 1-环己基-3-[4-(1-羟基乙基)苯基]磺酰基脲 | (-)-hydroxyhexamide | 968-80-9 | C15H22N2O4S |
|
| 1-环丙基-3-(3-(5-(吗啉甲基)-1H-苯并[D]咪唑-2-基)-1H-吡唑-4-基)脲 | 1-cyclopropyl-3-[3-(5-morpholin-4-ylmethyl-1H-benzoimidazol-2-yl)-1H-pyrazol-4-yl]urea L-lactate | 896466-76-5 | C3H6O3*C19H23N7O2 |
|
| 1-氮杂-二环[2.2.2]辛烷-4-羧酸盐酸盐 | quinuclidine-4-carboxylic acid hydrochloride | 40117-63-3 | C8H13NO2*ClH |
|
| 1-叔丁氧羰基-4-哌啶乙酸 | 2-(1-(tert-butoxycarbonyl)piperidin-4-yl)acetic acid | 157688-46-5 | C12H21NO4 |
|
| 1-十八碳酰基-2-[顺式-9-十八碳烯酰基]-Sn-甘油-3-磷酰胆碱 | 1-stearoyl-2-oleoyl-sn-glycero-3-phosphocholine | 56421-10-4 | C44H86NO8P |
|
| 1-乙基-7-[2-甲基-6-(4H-1,2,4-三唑-3-基)吡啶-3-基]-3,4-二氢吡嗪并[2,3-b]吡嗪-2(1H)-酮 | 1-ethyl-7-(2-methyl-6-(1H-1,2,4-triazol-3-yl)pyridin-3-yl)-3,4-dihydropyrazino[2,3-b]pyrazin-2(1H)-one. | 1228013-15-7 | C16H16N8O |
|
| 1-乙基-2-[[[3-乙基-5-(3-甲基-2(3H)-苯并噻唑基]-4-氧代-2-噻唑啉亚基]甲基]-氯化吡啶鎓 | 3-ethyl-2-[(1-ethylpyridin-1-ium-2-yl)methylidene]-5-(3-methyl-1,3-benzothiazol-2-ylidene)-1,3-thiazolidin-4-one;chloride | 147366-41-4 | C21H22ClN3OS2 |
|
| 1-乙基-1H-吲哚-6-甲醛 | 1-ethyl-1H-indole-6-carbaldehyde | 854778-47-5 | C11H11NO |
|
| 1-乙基-1,2-二氢-4-羟基-2-氧代-3-喹啉羧酸 2-(1-氧代十三烷基)酰肼 | 1-ethyl-4-hydroxy-2-oxo-N'-tridecanoyl-1,2-dihydroquinoline-3-carbohydrazide | 331963-29-2 | C25H37N3O4 |
|
| 1-丁基-3-氯-4-(4-苯基哌啶-1-基)吡啶-2(1H)-酮 | 1-butyl-3-chloro-4-(4-phenylpiperidin-1-yl)pyridin-2(1H)-one | 1127498-03-6 | C20H25ClN2O |
|
| 1-[β-(3-(4-甲氧基苯基)丙氧基)-4-甲氧苯]-1H-咪唑盐酸盐 | SKF 96365 | 130495-35-1 | C22H26N2O3*ClH |
|
| 1-[[3,4-二氟-2-[(2-氟-4-碘苯基)氨基]苯基]羰基]-3-(哌啶-2-基)氮杂环丁-3-醇 | cobimetinib | 934662-91-6 | C21H21F3IN3O2 |
|
| 1-[[1,5-二(4-氯苯基)-2-甲基-1H-吡咯-3-基]甲基]-4-甲基哌嗪 | 1-((1,5-bis(4-chlorophenyl)-2-methyl-1H-pyrrol-3-yl)methyl)-4-methylpiperazine | 146204-42-4 | C23H25Cl2N3 |
|
| 1-[[(2S,3S,4S)-3-乙基-4-氟-5-氧代-2-吡咯烷基]甲氧基]-7-甲氧基-6-异喹啉羧酰胺 | PF06650833 | 1817626-54-2 | C18H20FN3O4 |
|
| 1-[6-(3,5-二氯-4-羟基苯基)-4-[[反式-4-[(二甲基氨基)甲基]环己基]氨基]-1,5-萘啶-3-基]-乙酮 | OTSSP167 | 1431697-89-0 | C25H28Cl2N4O2 |
|
| 1-[4-[2-羟基-3-(5-喹啉基氧基)丙基]-1-哌嗪基]-2,2-二苯基乙酮 | 5-[3-(4-(2,2-diphenylacetyl)piperazine-1-yl)-2-hydroxypropoxy]quinoline | 129716-58-1 | C30H31N3O3 |
|
| 1-[4-(2-萘基)-2-嘧啶基]-4-哌啶甲胺 | WAY-262611 | 1123231-07-1 | C20H22N4 |
|
| 1-[3-[2-[4-(2-甲基-5-喹啉基)-1-哌嗪基]乙基]苯基]-2-咪唑烷酮 | 1-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-2-imidazolidinone | 844903-58-8 | C25H29N5O |
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| 1-[3-(甲基硫代)苯基]甲胺 | 3-methylthiobenzylamine | 93071-78-4 | C8H11NS |
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| 1-[3-(4-溴-1-甲基-1H-吡唑-5-基)-4-甲氧基苯基]-3-(2,4-二氟苯基)脲 | Nelotanserin | 839713-36-9 | C18H15BrF2N4O2 |
|
| 1-[3,5-二(1,1-二甲基乙基)-4-羟基苯基]-2-[2-[(3-羟基丙基)氨基]-5,6-二甲基-1H-苯并咪唑-1-基]-乙酮 | AJW-200 | 758679-97-9 | C28H39N3O3 |
|
| 1-[2-氟-4-(1H-吡唑-1-基)苯基]-5-甲氧基-3-(1-苯基-1H-吡唑-5-基)哒嗪-4(1H)-酮 | 1-[2-fluoro-4-(1H-pyrazol-1-yl)phenyl]-5-methoxy-3-(1-phenyl-1H-pyrazol-5-yl)pyridazin-4(1H)-one | 1238697-26-1 | C23H17FN6O2 |
|
| 1-[2-(二苯基甲氧基)乙基]-4-(3-苯基-2-丙苯基)-哌嗪 | 1-[2-(diphenylmethoxy)ethyl]-4-(3-phenyl-2-propenyl)piperazine | 67469-57-2 | C28H32N2O |
|
| 1-[2-(3,4-二甲氧基苯基)乙基]-4-(3-苯基丙基)哌嗪盐酸盐 | 1-(3,4-Dimethoxyphenethyl)-4-(3-phenylpropyl)piperazine dihydrochloride | 165377-44-6 | C23H34Cl2N2O2 |
|
| 1-[1-[(5-甲氧基-1H-吲哚-2-基)羰基]哌啶-4-基]-2-甲基丙-2-醇 | ASP9521 | 1126084-37-4 | C19H26N2O3 |
|
| 1-[1-[(2-氨基吡啶-4-基)甲基]-1H-吲哚-4-基]-3-(5-溴-2-甲氧基苯基)脲 | 1-[1-(2-amino-pyridin-4-ylmethyl)-1H-indol-4-yl]-3-(5-bromo-2-methoxy-phenyl)-urea | 900573-88-8 | C22H20BrN5O2 |
|
| 1-[1-(1-甲基环辛基)-4-哌啶基]-2-[(3R)-3-哌啶基]-1H-苯并咪唑 | 1-[1-(1-methylcyclooctyl)-4-piperidinyl]-2-[(3R)-3-piperidinyl]-1H-benzimidazole | 1028969-49-4 | C26H40N4 |
|
| 1-[(4-氯苯基)甲基]-5-(三氟甲基)苯并咪唑-2-胺 | 2-amino-1-(4-chlorobenzyl)-5-trifluoromethylbenzimidazole | 150493-34-8 | C15H11ClF3N3 |
|
| 1-[(4,6-二甲基-5-嘧啶基)羰基]-4-[(3S)-4-[(1R)-2-甲氧基-1-[4-(三氟甲基)苯基]乙基]-3-甲基-1-哌嗪基]-4-甲基哌啶马来酸盐 | Vicriviroc maleate | 599179-03-0 | C32H42F3N5O6 |
|
| 1-[(3S)-3-[4-氨基-3-[2-(3,5-二甲氧基苯基)乙炔基]-1H-吡唑并[3,4-d]嘧啶-1-基]-1-吡咯烷基]-2-丙烯-1-酮 | futibatinib | 1448169-71-8 | C22H22N6O3 |
|
| 1-Fmoc-2-羟甲基哌啶 | 1-Fmoc-2-(hydroxymethyl)piperidine | 170867-95-5 | C21H23NO3 |
|
| 1-FMOC-3-吡咯烷甲酸 | 1-(9H-fluoren-9-ylmethoxycarbonyl)pyrrolidine-3-carboxylic acid | 885951-89-3 | C20H19NO4 |
|
| 1-Boc-L-吖啶-2-羧酸 | (S)-1-(t-butoxycarbonyl)azetidine-2-carboxylic acid | 51077-14-6 | C9H15NO4 |
|
| 1-(十四碳酰氧基)-2,5-吡咯烷二酮 | N-succinimidyl myristate | 69888-86-4 | C18H31NO4 |
|
| 1-(二苯基甲基)-4-(1-氧代-3,3-二苯基丙基)哌嗪 | NP118809 | 41332-24-5 | C32H32N2O |
|
| 1-(beta-D-呋喃木糖基)胞嘧啶 | 1-(β-D-xylo-pentofuranosyl)cytosine | 3530-56-1 | C9H13N3O5 |
|
| 1-(4-苯甲酰基哌嗪-1-基)-2-[4-甲氧基-7-(3-甲基-1H-1,2,4-三氮唑-1-基)-1H-吡咯并[2,3-c]吡啶-3-基)乙烷-1,2-二酮 | 1-(4-benzoylpiperazin-1-yl)-2-(4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl)-ethane-1,2-dione | 701213-36-7 | C24H23N7O4 |
|
| 1-(4-羟基环己基)-2-[[5-(2-三氟甲氧基苯基)-1H-吲唑-3-基]氨基]-1H-苯并咪唑-5-羧酸(3-甲基丁基)酰胺 | 2-(5-(2-(trifluoromethoxy)phenyl)-1H-indazol-3-ylamino)-1-(4-hydroxycyclohexyl)-N-isopentyl-1H-benzo[d]imidazole-5-carboxamide | 1012104-68-5 | C33H35F3N6O3 |
|
| 1-(4-甲氧基苯基)-2-甲基-3-硝基-1H-吲哚-6-醇 | ID-8 | 147591-46-6 | C16H14N2O4 |
|
| 1-(4-氰基-2-吡啶基)-5-氧代-L-脯氨酰-2-(2-氯苯基)-N-(3,3-二氟环丁基)-N2-(5-氟-3-吡啶基)甘氨酰胺 | (2S)-N-(1-(2-chlorophenyl)-2-((3,3-difluorocyclobutyl)amino)-2-oxoethyl)-1-(4-cyanopyridin-2-yl)-N-(5-fluoropyridin-3-yl)-5-oxopyrrolidine-2-carboxamide | 1448346-63-1 | C28H22ClF3N6O3 |
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