激动剂抑制剂-摩熵化学

中文名称	英文名称	CAS号	化学式
(8S,10S)-8-乙酰基-7,8,9,10-四氢-6,8,11-三羟基-1-甲氧基-10-[[2,3,6-三脱氧-3-[[[[4-(beta-D-吡喃半乳糖基氧基)-3-硝基苯基]甲氧基]羰基]氨基]-alpha-L-来苏-己糖吡喃糖苷]氧基]-5,12-并四苯醌	[3-Nitro-4-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]methyl N-[(2S,3S,4S,6R)-6-[[(1S,3S)-3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]-3-hydroxy-2-methyloxan-4-yl]carbamate	290304-24-4	C₄₁H₄₄N₂O₂₀
(8R,9S)-5-氟-8-(4-氟苯基)-2,7,8,9-四氢-9-(1-甲基-1H-1,2,4-三唑-5-基)-3H-吡啶并[4,3,2-de]酞嗪-3-酮	(8R,9S)-5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-8,9-dihydro-2H-pyrido[4,3 ,2-de] phthalazin-3(7H)-one	1207456-00-5	C₁₉H₁₄F₂N₆O
(6aR)-3-异丙基-1-(甲基磺酰基)-4-[(2E)-4-(1-哌啶基)-2-丁烯酰]六氢吡咯并[3,2-b]吡咯-2(1H)-酮盐酸盐(1:1)	Pyrrolo(3,2-b)pyrrol-2(1H)-one, hexahydro-3-(1-methylethyl)-1-(methylsulfonyl)-4-((2E)-1-oxo-4-(1-piperidinyl)-2-butenyl)-, (3S,3aS,6aR)-	198062-54-3	C₁₉H₃₁N₃O₄S
(6R)-6-[[[(4-氯苯基)磺酰基]氨基]-5,6,7,8-四氢-2-甲基-1-萘丙酸	Terutroban	165538-40-9	C₂₀H₂₂ClNO₄S
(5Z,8Z,11Z,14Z)-N-环丙基-5,8,11,14-二十碳四烯酰胺	arachidonylcyclopropylamide	229021-64-1	C₂₃H₃₇NO
(5R)-5-[(7-氯-1H-吲哚-3-基)甲基]-3-甲基-2,4-咪唑烷二酮	(R)-5-((7-chloro-1H-indol-3-yl)methyl)-3-methylimidazolidine-2,4-dione	852391-19-6	C₁₃H₁₂ClN₃O₂
(5-甲氧基-1H-吲哚-2-基)苯基甲酮	(5-methoxy-1H-indol-2-yl)(phenyl)methanone	74588-78-6	C₁₆H₁₃NO₂
(4R)-甘氨酰基-4-(苯甲酰基氨基)-L-脯氨酸盐酸盐	Danegaptide hydrochloride	943133-81-1	C₁₄H₁₇N₃O₄*ClH
(4-环丙基哌嗪-1-基)-[4-(吗啉-4-基甲基)苯基]甲酮	Bavisant	929622-08-2	C₁₉H₂₇N₃O₂
(4-溴苯基)[2-氟-4-[[6-(甲基-2-丙烯基氨基)己基]氧基]苯基]甲酮	[4-[6-(allyl-methyl-amino)-hexyloxy]-2-fluoro-phenyl]-(4-bromo-phenyl)-methanone	161582-11-2	C₂₃H₂₇BrFNO₂
(3aR,4S,7aR)-八氢-4-羟基-4-[2-(3-甲基苯基)乙炔基]-1H-吲哚-1-羧酸甲酯	mavoglurant	543906-09-8	C₁₉H₂₃NO₃
(3S-反式)-1,4-二氢-7-[3-甲氧基-4-(甲基氨基)-1-吡咯烷基]-4-氧代-1-(2-噻唑基)-1,8-萘啶-3-羧酸单盐酸盐	AG-7352 hydrochloride	175519-16-1	C₁₈H₁₉N₅O₄S*ClH
(3S,5R,8R,9S,10S,13R,14S,17R)-17-(3-呋喃基)-10,13-二甲基-2,3,4,5,6,7,8,9,11,12,15,16-十二氢-1H-环戊二烯并[a]菲-3,14,17-三酚	17-β-(3-furyl)-5-β-androstane-3-β, 14-β, 17-α-triol	156722-18-8	C₂₃H₃₄O₄
(3S)-N-[2-[2-(二甲基氨基)乙氧基]-4-(1H-吡唑-4-基)苯基]-3,4-二氢-6-甲氧基-2H-1-苯并吡喃-3-甲酰胺	Chroman 1	1273579-40-0	C₂₄H₂₈N₄O₄
(3S)-2-(2,2-二苯基乙酰基)-1,2,3,4-四氢-6-甲氧基-5-苄氧基-3-异喹啉羧酸	EMA401	1316755-16-4	C₃₂H₂₉NO₅
(3R,4R)-4-氨基-1-[[4-[(3-甲氧基苯基)氨基]吡咯并[2,1-f][1,2,4]三嗪-5-基]甲基]哌啶-3-醇	BMS-690514	859853-30-8	C₁₉H₂₄N₆O₂
(3R)-N-[5-氯-4-(5-氟-2-甲氧基苯基)-2-吡啶基]-3-哌啶甲酰胺	(3R)-N-[5-chloro-4-(5-fluoro-2-methoxyphenyl)pyridin-2-yl]piperidine-3-carboxamide	1269815-17-9	C₁₈H₁₉ClFN₃O₂
(3R)-1,2,3,4-四氢-7-羟基-N-[(1S)-1-[[(3R,4R)-4-(3-羟基苯基)-3,4-二甲基-1-哌啶基]甲基]-2-甲基丙基]-3-异喹啉甲酰胺盐酸盐	JDTic dihydrochloride	785835-79-2	C28H41Cl2N3O3
(3E)-5-氯-3-[[5-[3-[(六氢-4-甲基-1H-14-二氮杂革-1-基)羰基]苯基]-2-呋喃]亚甲基]-1,3-二氢-2H-吲哚-2-酮	CX-6258	1202916-90-2	C₂₆H₂₄ClN₃O₃
(2S,5R)-5-(4-((2-氟苄基)氧基)苯基)吡咯烷-2-甲酰胺盐酸盐	(5R)-5-(4-{[(2-fluorophenyl)methyl]oxy}phenyl)-L-prolinamide hydrochloride	934240-31-0	C₁₈H₁₉FN₂O₂*ClH
(2S,4R)-1-(2-氨基乙酰基)-4-苯甲酰胺吡咯烷-2-甲酸	(2S,4R)-1-(2-aminoacetyl)-4-benzoylamino-pyrrolidine-2-carboxylic acid	943134-39-2	C₁₄H₁₇N₃O₄
(2S,3S,4R,5R)-2-(4-氨基-5H-吡咯并[3,2-D]嘧啶-7-基)-5-(羟基甲基)-3,4-吡咯烷二醇单盐酸盐	(2S,3S,4R,5R)-2-(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)-5-(hydroxymethyl)pyrrolidine-3,4-diol dihydrochloride	222631-44-9	C₁₁H₁₅N₅O₃*2ClH
(2S,3S)-3-[[3-(异丙基)-7-[(苯基甲基)氨基]吡唑并[1,5-a]嘧啶-5-基]氨基]-1,2,4-丁三醇	BS-194	1092443-55-4	C₂₀H₂₇N₅O₃
(2S,3S)-2-(3-氯苯基)-3,5,5-三甲基吗啉-2-醇	radafaxine	192374-14-4	C₁₃H₁₈ClNO₂
(2S,3R,4R,5S,6R)-2-(4-氯-3-(4-乙氧基苄基)苯基)-6-(甲基硫代)四氢-2H-吡喃-3,4,5-三醇	sotagliflozin	1018899-04-1	C₂₁H₂₅ClO₅S
(2S)-N6,N6,2-三甲基-1,2-二氢-1,3,5-三嗪-4,6-二胺	Imeglimin	775351-65-0	C₆H₁₃N₅
(2S)-N-[(1R)-1-(1,3-苯并二氧戊环-5-基)丁基]-3,3-二乙基-2-[4-[(4-甲基-1-哌嗪基)羰基]苯氧基]-4-氧代-1-氮杂环丁烷甲酰胺	L-694,458	157341-41-8	C₃₁H₄₀N₄O₆
(2S)-2-氨基-2-[(1S,2S)-2-羧基环丙-1-基]-3-(吨-9-基)丙酸	2-[(1S,2S)-2-carboxycyclopropyl]-3-(9H-xanthen-9-yl)-D-alanine	201943-63-7	C₂₀H₁₉NO₅
(2S)-2-[[((2S)-6,8-二氟-1,2,3,4-四氢-2-萘基]氨基]-N-[1-[2-[(2,2-二甲基丙基))氨基]-1,1-二甲基乙基]-1H-咪唑-4-基]戊酰胺二氢溴化物	Nirogacestat Hydrobromide	1962925-29-6	C27H43Br2F2N5O
(2S)-2-(3-氨基丙基)-5-(2,5-二氟苯基)-N-甲氧基-N-甲基-2-苯基-1,3,4-噻二唑-3(2H)-甲酰胺	filanesib	885060-09-3	C₂₀H₂₂F₂N₄O₂S
(2S)-2-((4-(((2,7-二甲基-4-氧代-1,4-二氢喹唑啉-6-基)甲基)(丙-2-炔基)氨基)-2-氟苯甲酰)氨基)-4-(1H-四唑-5-基)丁酸	narlaprevir	865466-24-6	C₃₆H₆₁N₅O₇S
(2R,4S)-N-[1-[3,5-双(三氟甲基)苯甲酰]-2-(4-氯苄基)哌啶-4-基]喹啉-4-甲酰胺	(2R,4S)-N-[1-(3,5-bis(trifluoromethyl)benzoyl)-2-(4-chlorobenzyl)-4-piperidinyl]quinoline-4-carboxamide	177707-12-9	C₃₁H₂₄ClF₆N₃O₂
(2R,4'R,8'aR)-1-[2-[4-[[2-(2,4-二氯苯氧基)乙酰基]氨基]苯基]乙酰基]四氢-6'-氧代螺[吡咯烷-2,7'(6'H)-[2H]吡咯并[2,1-b][1,3]噻嗪]-4'-甲酰胺	ST2825	894787-30-5	C₂₇H₂₈Cl₂N₄O₅S
(2R,3R,4R,5S)-1-丁基-2-(羟基甲基)-3,4,5-哌啶三醇盐酸盐(1:1)	miglustat hydrochloride	210110-90-0	C₁₀H₂₁NO₄*ClH
(2R,2'R,3R,3'R,4S,4'S,5R,5'R,6S,6'S)-6,6'-硫代双(4-(4-(3-氟苯基)-1H-1,-1H-1,2,3-三唑-1-基)-2-(羟甲基)四氢-2H-吡喃-3,5-二醇)	TD139	1450824-22-2	C₂₈H₃₀F₂N₆O₈S
(2R)-2-[[6-[[(5-甲基噻吩-2-基)甲基]氨基]-9-丙基-9H-嘌呤-2-基]氨基]丁烷-1-醇	(2R)-2-[(6-{[(5-methylthiophen-2-yl)methyl]amino}-9-propyl-9H-purin-2-yl)amino]butan-1-ol	1402821-41-3	C₁₈H₂₆N₆OS
(2R)-2-(3-氨基丙基)-5-(2,5-二氟苯基)-N-甲氧基-N-甲基-2-苯基-1,3,4-噻二唑-3(2H)-甲酰胺	(R)-Filanesib	885060-08-2	C₂₀H₂₂F₂N₄O₂S
(2R)-2,4-二甲基-1-哌嗪羧酸 4-[(3-氯-2-氟苯基)氨基]-7-甲氧基-6-喹唑啉基酯	AZD3759	1626387-80-1	C₂₂H₂₃ClFN₅O₃
(2R)-1-[[[4-氯-2-(脲基)苯氧基]甲基]羰基]-2-甲基-4-(4-氟苄基)哌嗪	1-(5-chloro-2-{2-[(2R)-4-(4-fluorobenzyl)-2-methylpiperazin-1-yl]-2-oxoethoxy}phenyl)urea	217645-70-0	C₂₁H₂₄ClFN₄O₃
(2E,5E)-2,5-二(2-噻吩基亚甲基)环戊酮	CCT007093	176957-55-4	C₁₅H₁₂OS₂
(2E,2'E)-1,1'-环己基亚基二[3-(3,4-二甲氧基苯基)-2-丙烯-1-酮]	FLLL32	1226895-15-3	C₂₈H₃₂O₆
(2E)-N-甲基-N-[(3-甲基-2-苯并呋喃基)甲基]-3-(5,6,7,8-四氢-7-氧代-1,8-萘啶-3-基)-2-丙烯酰胺	(2E)-N-methyl-N-[(3-methyl-1-benzofuran-2-yl)methyl]-3-(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)prop-2-enamide	620175-39-5	C₂₂H₂₁N₃O₃
(2E)-3-苯基-N-[2,2,2-三氯-1-[[[(4-氯苯基)氨基]硫代甲酰基]氨基]乙基]-2-丙烯酰胺	(E)-3-phenyl-N-[2,2,2-trichloro-1-[(4-chlorophenyl)carbamothioylamino]ethyl]prop-2-enamide	301359-91-1	C₁₈H₁₅Cl₄N₃OS
(2E)-3-(4-溴苯基)-1-[4--4-甲氧基苯甲酰基)-1-哌嗪基]-2-丙烯-1-酮	NIBR189	1599432-08-2	C₂₁H₂₁BrN₂O₃
(2E)-2-氰基-3-(3,4-二羟基苯基)-N-苯基-2-丙烯酰胺	α-cyano-(3,4-dihydroxy)-N-phenylcinnamide	133550-35-3	C₁₆H₁₂N₂O₃
(2-羟苯基)(吡咯烷-1-基)甲硫酮	o-hydroxythiobenzopyrrolidide	84783-01-7	C₁₁H₁₃NOS
(1S)-2-苯基-1-(1,3-噻唑-2-基)乙胺盐酸盐	Doe hydrochloride	135383-60-7	C₁₁H₁₂N₂S*ClH
(1S)-1,5-脱水-1-C-[4-氯-3-[[4-[2-(环丙氧基)乙氧基]苯基]甲基]苯基]-D-山梨醇	bexagliflozin	1118567-05-7	C₂₄H₂₉ClO₇
(1R,2S)-2-环己基-1-(4-(环丙基磺酰基)苯基)-N-(5-((2-(吡咯烷-1-基)乙基)硫代)噻唑-2-基)环丙烷羧酰胺	LY2608204	1234703-40-2	C₂₈H₃₇N₃O₃S₃
(1R,2R,3S,3AR,8BS)-6-[[(2S,3R,6R)-6-[(1R)-1,2-二羟基乙基]-3-甲氧基-1,4-二氧己环-2-基]氧基]-2,3,3A,8B-四氢-1,8B-二羟基-8-甲氧基-3A-(4-甲氧基苯基)-3-苯基-1H-环戊烯并[B]苯并呋喃-2-羧酸甲酯	(1R,2R,3S,3aR,8bS)-methyl 6-(((2S,3R,6R)-6-((R)-1,2-dihydroxyethyl)-3-methoxy-1,4-dioxan-2-yl)oxy)-1,8b-dihydroxy-8-methoxy-3a-(4-methoxyphenyl)-3-phenyl-2,3,3a,8b-tetrahydro-1H-cyclopenta[b]benzofuran-2-carboxylate	697235-38-4	C₃₄H₃₈O₁₃

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