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    —— (6R)-N-cyclohexyl-2-(4-ethylphenyl)-6-methyl-4-oxo-5-(3-propylsulfanylpropyl)-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C28H40N4O2S
    (6R)-N-cyclohexyl-2-(4-ethylphenyl)-6-methyl-4-oxo-5-(3-propylsulfanylpropyl)-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6R)-N-cyclooctyl-5-(3-fluorophenyl)-6-methyl-4-oxo-2-propan-2-yl-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C25H33FN4O2
    (6R)-N-cyclooctyl-5-(3-fluorophenyl)-6-methyl-4-oxo-2-propan-2-yl-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6S)-N-cyclohexyl-2-(4-ethylphenyl)-6-methyl-4-oxo-5-(4-propan-2-ylphenyl)-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C31H38N4O2
    (6S)-N-cyclohexyl-2-(4-ethylphenyl)-6-methyl-4-oxo-5-(4-propan-2-ylphenyl)-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6S)-2-tert-butyl-N-cyclooctyl-6-methyl-5-(3-methylsulfanylphenyl)-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C27H38N4O2S
    (6S)-2-tert-butyl-N-cyclooctyl-6-methyl-5-(3-methylsulfanylphenyl)-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6R)-5-[(3-chlorophenyl)methyl]-N-cyclooctyl-6-methyl-4-oxo-2-propan-2-yl-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C26H35ClN4O2
    (6R)-5-[(3-chlorophenyl)methyl]-N-cyclooctyl-6-methyl-4-oxo-2-propan-2-yl-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6S)-N-cyclooctyl-2-(furan-2-yl)-6-methyl-5-(2-methylphenyl)-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C27H32N4O3
    (6S)-N-cyclooctyl-2-(furan-2-yl)-6-methyl-5-(2-methylphenyl)-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6R)-5-(3-chloro-4-methylphenyl)-N-cyclooctyl-2-(furan-2-yl)-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C27H31ClN4O3
    (6R)-5-(3-chloro-4-methylphenyl)-N-cyclooctyl-2-(furan-2-yl)-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6R)-5-(3-chlorophenyl)-N-cyclooctyl-6-methyl-4-oxo-2-propan-2-yl-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C25H33ClN4O2
    (6R)-5-(3-chlorophenyl)-N-cyclooctyl-6-methyl-4-oxo-2-propan-2-yl-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6R)-N-cyclohexyl-2-(4-ethylphenyl)-6-methyl-4-oxo-5-[(2R)-2-phenylpropyl]-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C31H38N4O2
    (6R)-N-cyclohexyl-2-(4-ethylphenyl)-6-methyl-4-oxo-5-[(2R)-2-phenylpropyl]-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6R)-N-cyclooctyl-6-methyl-4-oxo-5-(2-phenylethyl)-2-propan-2-yl-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C27H38N4O2
    (6R)-N-cyclooctyl-6-methyl-4-oxo-5-(2-phenylethyl)-2-propan-2-yl-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6R)-N-cyclooctyl-5-(4-methoxyphenyl)-6-methyl-4-oxo-2-propan-2-yl-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C26H36N4O3
    (6R)-N-cyclooctyl-5-(4-methoxyphenyl)-6-methyl-4-oxo-2-propan-2-yl-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6S)-N-cycloheptyl-5-(4-ethylphenyl)-6-methyl-4-oxo-2-thiophen-2-yl-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C27H32N4O2S
    (6S)-N-cycloheptyl-5-(4-ethylphenyl)-6-methyl-4-oxo-2-thiophen-2-yl-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6R)-5-[(4-chlorophenyl)methyl]-N-cyclooctyl-6-methyl-4-oxo-2-propan-2-yl-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C26H35ClN4O2
    (6R)-5-[(4-chlorophenyl)methyl]-N-cyclooctyl-6-methyl-4-oxo-2-propan-2-yl-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6R)-N-cycloheptyl-5-(2,5-dimethylphenyl)-6-methyl-4-oxo-2-thiophen-2-yl-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C27H32N4O2S
    (6R)-N-cycloheptyl-5-(2,5-dimethylphenyl)-6-methyl-4-oxo-2-thiophen-2-yl-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6S)-N-cyclooctyl-5-[(4-fluorophenyl)methyl]-2-(furan-2-yl)-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C27H31FN4O3
    (6S)-N-cyclooctyl-5-[(4-fluorophenyl)methyl]-2-(furan-2-yl)-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6S)-2-tert-butyl-N-cyclooctyl-5-(2,4-dimethylphenyl)-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C28H40N4O2
    (6S)-2-tert-butyl-N-cyclooctyl-5-(2,4-dimethylphenyl)-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6S)-N-cyclooctyl-2-(furan-2-yl)-6-methyl-5-[(4-methylphenyl)methyl]-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C28H34N4O3
    (6S)-N-cyclooctyl-2-(furan-2-yl)-6-methyl-5-[(4-methylphenyl)methyl]-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6S)-2-tert-butyl-N-cyclooctyl-5-[(2-fluorophenyl)methyl]-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C27H37FN4O2
    (6S)-2-tert-butyl-N-cyclooctyl-5-[(2-fluorophenyl)methyl]-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6R)-N-cyclooctyl-5-[(4-methoxyphenyl)methyl]-6-methyl-4-oxo-2-propan-2-yl-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C27H38N4O3
    (6R)-N-cyclooctyl-5-[(4-methoxyphenyl)methyl]-6-methyl-4-oxo-2-propan-2-yl-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6R)-N-cyclooctyl-6-methyl-4-oxo-2-propan-2-yl-5-(3-propylsulfanylpropyl)-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C25H42N4O2S
    (6R)-N-cyclooctyl-6-methyl-4-oxo-2-propan-2-yl-5-(3-propylsulfanylpropyl)-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6S)-N-cyclooctyl-5-(2,4-dimethylphenyl)-6-methyl-4-oxo-2-thiophen-2-yl-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C28H34N4O2S
    (6S)-N-cyclooctyl-5-(2,4-dimethylphenyl)-6-methyl-4-oxo-2-thiophen-2-yl-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6R)-N-cyclooctyl-5-(2,5-dimethylphenyl)-6-methyl-4-oxo-2-propan-2-yl-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C27H38N4O2
    (6R)-N-cyclooctyl-5-(2,5-dimethylphenyl)-6-methyl-4-oxo-2-propan-2-yl-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6R)-2-tert-butyl-N-cyclooctyl-5-(2-methoxyethyl)-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C23H38N4O3
    (6R)-2-tert-butyl-N-cyclooctyl-5-(2-methoxyethyl)-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6R)-5-[(2-chlorophenyl)methyl]-N-cyclooctyl-6-methyl-4-oxo-2-propan-2-yl-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C26H35ClN4O2
    (6R)-5-[(2-chlorophenyl)methyl]-N-cyclooctyl-6-methyl-4-oxo-2-propan-2-yl-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6S)-N-cyclooctyl-2-(furan-2-yl)-5-[(4-methoxyphenyl)methyl]-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C28H34N4O4
    (6S)-N-cyclooctyl-2-(furan-2-yl)-5-[(4-methoxyphenyl)methyl]-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6R)-N-cyclohexyl-2-(4-ethylphenyl)-5-[(2-fluorophenyl)methyl]-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C29H33FN4O2
    (6R)-N-cyclohexyl-2-(4-ethylphenyl)-5-[(2-fluorophenyl)methyl]-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6R)-N-cyclooctyl-6-methyl-5-(2-methylphenyl)-4-oxo-2-propan-2-yl-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C26H36N4O2
    (6R)-N-cyclooctyl-6-methyl-5-(2-methylphenyl)-4-oxo-2-propan-2-yl-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6S)-2-tert-butyl-N-cyclohexyl-5-(2,4-dimethylphenyl)-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C26H36N4O2
    (6S)-2-tert-butyl-N-cyclohexyl-5-(2,4-dimethylphenyl)-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6S)-N-cycloheptyl-5-(3,4-dimethylphenyl)-6-methyl-4-oxo-2-thiophen-2-yl-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C27H32N4O2S
    (6S)-N-cycloheptyl-5-(3,4-dimethylphenyl)-6-methyl-4-oxo-2-thiophen-2-yl-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6S)-2-tert-butyl-N-cyclooctyl-5-[(2-ethoxyphenyl)methyl]-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C29H42N4O3
    (6S)-2-tert-butyl-N-cyclooctyl-5-[(2-ethoxyphenyl)methyl]-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6R)-N-cyclooctyl-2-(4-ethylphenyl)-6-methyl-4-oxo-5-[[(2R)-oxolan-2-yl]methyl]-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C29H40N4O3
    (6R)-N-cyclooctyl-2-(4-ethylphenyl)-6-methyl-4-oxo-5-[[(2R)-oxolan-2-yl]methyl]-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6S)-5-benzyl-N-cyclohexyl-2-(furan-2-yl)-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C25H28N4O3
    (6S)-5-benzyl-N-cyclohexyl-2-(furan-2-yl)-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6S)-N-cyclooctyl-2-(4-methoxyphenyl)-6-methyl-4-oxo-5-[[(2R)-oxolan-2-yl]methyl]-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C28H38N4O4
    (6S)-N-cyclooctyl-2-(4-methoxyphenyl)-6-methyl-4-oxo-5-[[(2R)-oxolan-2-yl]methyl]-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6R)-N-cyclooctyl-2-(4-ethylphenyl)-5-(3-methoxypropyl)-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C28H40N4O3
    (6R)-N-cyclooctyl-2-(4-ethylphenyl)-5-(3-methoxypropyl)-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6S)-5-[(4-chlorophenyl)methyl]-N-cycloheptyl-6-methyl-4-oxo-2-thiophen-2-yl-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C26H29ClN4O2S
    (6S)-5-[(4-chlorophenyl)methyl]-N-cycloheptyl-6-methyl-4-oxo-2-thiophen-2-yl-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6R)-2-tert-butyl-N-cyclooctyl-5-(2,4-dimethylphenyl)-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C28H40N4O2
    (6R)-2-tert-butyl-N-cyclooctyl-5-(2,4-dimethylphenyl)-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6S)-5-(3-chloro-2-methylphenyl)-N-[(2-methoxyphenyl)methyl]-6-methyl-4-oxo-2-phenyl-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C29H27ClN4O3
    (6S)-5-(3-chloro-2-methylphenyl)-N-[(2-methoxyphenyl)methyl]-6-methyl-4-oxo-2-phenyl-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6S)-N-cyclooctyl-5-(3,5-dimethylphenyl)-2-(furan-2-yl)-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C28H34N4O3
    (6S)-N-cyclooctyl-5-(3,5-dimethylphenyl)-2-(furan-2-yl)-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6R)-N-cyclohexyl-5-(2,4-difluorophenyl)-2-(4-ethylphenyl)-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C28H30F2N4O2
    (6R)-N-cyclohexyl-5-(2,4-difluorophenyl)-2-(4-ethylphenyl)-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6R)-N-cyclooctyl-2-(4-methoxyphenyl)-5-(3-methoxypropyl)-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C27H38N4O4
    (6R)-N-cyclooctyl-2-(4-methoxyphenyl)-5-(3-methoxypropyl)-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6R)-N-cyclooctyl-5-(3,4-dimethylphenyl)-6-methyl-4-oxo-2-thiophen-2-yl-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C28H34N4O2S
    (6R)-N-cyclooctyl-5-(3,4-dimethylphenyl)-6-methyl-4-oxo-2-thiophen-2-yl-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6S)-N-cyclooctyl-5-(2,4-dimethylphenyl)-2-(furan-2-yl)-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C28H34N4O3
    (6S)-N-cyclooctyl-5-(2,4-dimethylphenyl)-2-(furan-2-yl)-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6R)-N-cyclohexyl-2-(4-ethylphenyl)-6-methyl-4-oxo-5-(3-phenylpropyl)-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C31H38N4O2
    (6R)-N-cyclohexyl-2-(4-ethylphenyl)-6-methyl-4-oxo-5-(3-phenylpropyl)-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6S)-5-(3-chloro-2-methylphenyl)-N-cycloheptyl-6-methyl-4-oxo-2-thiophen-2-yl-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C26H29ClN4O2S
    (6S)-5-(3-chloro-2-methylphenyl)-N-cycloheptyl-6-methyl-4-oxo-2-thiophen-2-yl-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6S)-N-cyclooctyl-2-(furan-2-yl)-6-methyl-5-(3-methylsulfanylphenyl)-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C27H32N4O3S
    (6S)-N-cyclooctyl-2-(furan-2-yl)-6-methyl-5-(3-methylsulfanylphenyl)-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6S)-N-cyclohexyl-2-(4-ethylphenyl)-6-methyl-4-oxo-5-[(1S)-1-phenylethyl]-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C30H36N4O2
    (6S)-N-cyclohexyl-2-(4-ethylphenyl)-6-methyl-4-oxo-5-[(1S)-1-phenylethyl]-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6R)-N-cyclohexyl-2-(4-ethylphenyl)-6-methyl-5-[(4-methylphenyl)methyl]-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C30H36N4O2
    (6R)-N-cyclohexyl-2-(4-ethylphenyl)-6-methyl-5-[(4-methylphenyl)methyl]-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6S)-5-(3-chlorophenyl)-N-cyclooctyl-2-(furan-2-yl)-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C26H29ClN4O3
    (6S)-5-(3-chlorophenyl)-N-cyclooctyl-2-(furan-2-yl)-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6S)-N-cyclooctyl-2-(4-ethylphenyl)-6-methyl-4-oxo-5-[[(2S)-oxolan-2-yl]methyl]-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C29H40N4O3
    (6S)-N-cyclooctyl-2-(4-ethylphenyl)-6-methyl-4-oxo-5-[[(2S)-oxolan-2-yl]methyl]-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6R)-N-cyclooctyl-5-(2,4-difluorophenyl)-6-methyl-4-oxo-2-propan-2-yl-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C25H32F2N4O2
    (6R)-N-cyclooctyl-5-(2,4-difluorophenyl)-6-methyl-4-oxo-2-propan-2-yl-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide