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    —— (6S)-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-2-N-[3-(4-methylpiperazin-1-yl)propyl]-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C25H34FN7O3
    (6S)-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-2-N-[3-(4-methylpiperazin-1-yl)propyl]-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-6-N-cyclopentyl-5-ethyl-6-methyl-4-oxo-2-N-(3-piperidin-1-ylpropyl)-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C24H38N6O3
    (6R)-6-N-cyclopentyl-5-ethyl-6-methyl-4-oxo-2-N-(3-piperidin-1-ylpropyl)-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-6-N-cyclopentyl-2-N-(3-ethoxypropyl)-5-ethyl-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C21H33N5O4
    (6S)-6-N-cyclopentyl-2-N-(3-ethoxypropyl)-5-ethyl-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-6-N-benzyl-5,6-dimethyl-2-N-(2-morpholin-4-ylethyl)-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C23H30N6O4
    (6R)-6-N-benzyl-5,6-dimethyl-2-N-(2-morpholin-4-ylethyl)-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-6-N-cyclopentyl-2-N-[(4-ethoxyphenyl)methyl]-6-methyl-4-oxo-5-propyl-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C26H35N5O4
    (6R)-6-N-cyclopentyl-2-N-[(4-ethoxyphenyl)methyl]-6-methyl-4-oxo-5-propyl-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-6-N-benzyl-5,6-dimethyl-4-oxo-2-N-(3-phenylpropyl)-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C26H29N5O3
    (6S)-6-N-benzyl-5,6-dimethyl-4-oxo-2-N-(3-phenylpropyl)-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-N-cyclopentyl-2-(4-ethylpiperazine-1-carbonyl)-6-methyl-4-oxo-5-propyl-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C23H36N6O3
    (6S)-N-cyclopentyl-2-(4-ethylpiperazine-1-carbonyl)-6-methyl-4-oxo-5-propyl-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6S)-6-N-cyclopentyl-2-N-(4-ethoxyphenyl)-5-ethyl-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C24H31N5O4
    (6S)-6-N-cyclopentyl-2-N-(4-ethoxyphenyl)-5-ethyl-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-6-N-cyclopentyl-5-ethyl-2-N-[(2-fluorophenyl)methyl]-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C23H28FN5O3
    (6R)-6-N-cyclopentyl-5-ethyl-2-N-[(2-fluorophenyl)methyl]-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-5,6-dimethyl-6-N-[(4-methylphenyl)methyl]-4-oxo-2-N-(3-propylsulfanylpropyl)-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C24H33N5O3S
    (6S)-5,6-dimethyl-6-N-[(4-methylphenyl)methyl]-4-oxo-2-N-(3-propylsulfanylpropyl)-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-2-N-benzyl-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C24H24FN5O3
    (6R)-2-N-benzyl-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-6-N-[(4-fluorophenyl)methyl]-2-N-[2-(2-methoxyphenyl)ethyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C26H28FN5O4
    (6S)-6-N-[(4-fluorophenyl)methyl]-2-N-[2-(2-methoxyphenyl)ethyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-2-N-[(3-ethoxy-4-methoxyphenyl)methyl]-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C27H30FN5O5
    (6R)-2-N-[(3-ethoxy-4-methoxyphenyl)methyl]-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-2-N-(2-pyrrolidin-1-ylethyl)-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C23H29FN6O3
    (6R)-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-2-N-(2-pyrrolidin-1-ylethyl)-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-5,6-dimethyl-2-N-[(2-methylphenyl)methyl]-6-N-[(4-methylphenyl)methyl]-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C26H29N5O3
    (6S)-5,6-dimethyl-2-N-[(2-methylphenyl)methyl]-6-N-[(4-methylphenyl)methyl]-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-2-N-[(3-fluorophenyl)methyl]-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C24H23F2N5O3
    (6S)-2-N-[(3-fluorophenyl)methyl]-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-2-N-[3-(4-ethylpiperazin-1-yl)propyl]-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C26H36FN7O3
    (6R)-2-N-[3-(4-ethylpiperazin-1-yl)propyl]-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-6-N-benzyl-2-N-[(3,4-dimethoxyphenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C26H29N5O5
    (6R)-6-N-benzyl-2-N-[(3,4-dimethoxyphenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-6-N-benzyl-5,6-dimethyl-4-oxo-2-N-(3-pyrrolidin-1-ylpropyl)-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C24H32N6O3
    (6S)-6-N-benzyl-5,6-dimethyl-4-oxo-2-N-(3-pyrrolidin-1-ylpropyl)-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-5,6-dimethyl-N-(3-methylbutyl)-4-oxo-2-(piperidine-1-carbonyl)-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C20H31N5O3
    (6R)-5,6-dimethyl-N-(3-methylbutyl)-4-oxo-2-(piperidine-1-carbonyl)-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6S)-2-N-cycloheptyl-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C24H30FN5O3
    (6S)-2-N-cycloheptyl-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-6-N-benzyl-5,6-dimethyl-4-oxo-2-N-(3-piperidin-1-ylpropyl)-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C25H34N6O3
    (6R)-6-N-benzyl-5,6-dimethyl-4-oxo-2-N-(3-piperidin-1-ylpropyl)-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-6-N-benzyl-5,6-dimethyl-4-oxo-2-N-propan-2-yl-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C20H25N5O3
    (6R)-6-N-benzyl-5,6-dimethyl-4-oxo-2-N-propan-2-yl-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-5,6-dimethyl-6-N-[(4-methylphenyl)methyl]-2-N-(2-morpholin-4-ylethyl)-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C24H32N6O4
    (6S)-5,6-dimethyl-6-N-[(4-methylphenyl)methyl]-2-N-(2-morpholin-4-ylethyl)-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-5,6-dimethyl-2-N-[(2-methylphenyl)methyl]-6-N-[(4-methylphenyl)methyl]-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C26H29N5O3
    (6R)-5,6-dimethyl-2-N-[(2-methylphenyl)methyl]-6-N-[(4-methylphenyl)methyl]-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-2-N-(2-morpholin-4-ylethyl)-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C23H29FN6O4
    (6R)-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-2-N-(2-morpholin-4-ylethyl)-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-5,6-dimethyl-6-N-[(4-methylphenyl)methyl]-4-oxo-2-N-(3-propan-2-yloxypropyl)-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C24H33N5O4
    (6S)-5,6-dimethyl-6-N-[(4-methylphenyl)methyl]-4-oxo-2-N-(3-propan-2-yloxypropyl)-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-5,6-dimethyl-6-N-[(4-methylphenyl)methyl]-4-oxo-2-N-(pyridin-2-ylmethyl)-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C24H26N6O3
    (6R)-5,6-dimethyl-6-N-[(4-methylphenyl)methyl]-4-oxo-2-N-(pyridin-2-ylmethyl)-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-6-N-cyclopentyl-2-N-[(2,4-dimethoxyphenyl)methyl]-6-methyl-4-oxo-5-propyl-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C26H35N5O5
    (6R)-6-N-cyclopentyl-2-N-[(2,4-dimethoxyphenyl)methyl]-6-methyl-4-oxo-5-propyl-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-6-N-cyclopentyl-5-ethyl-2-N-[(4-methoxyphenyl)methyl]-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C24H31N5O4
    (6S)-6-N-cyclopentyl-5-ethyl-2-N-[(4-methoxyphenyl)methyl]-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-6-N-benzyl-2-N-[2-(furan-2-yl)ethyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C23H25N5O4
    (6S)-6-N-benzyl-2-N-[2-(furan-2-yl)ethyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-6-N-benzyl-2-N-[(2-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C24H24FN5O3
    (6S)-6-N-benzyl-2-N-[(2-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-6-N-cyclopentyl-5-ethyl-6-methyl-4-oxo-2-N-(3-propan-2-yloxypropyl)-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C22H35N5O4
    (6R)-6-N-cyclopentyl-5-ethyl-6-methyl-4-oxo-2-N-(3-propan-2-yloxypropyl)-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-6-N-cyclopentyl-6-methyl-4-oxo-5-propyl-2-N-(2-thiophen-2-ylethyl)-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C23H31N5O3S
    (6R)-6-N-cyclopentyl-6-methyl-4-oxo-5-propyl-2-N-(2-thiophen-2-ylethyl)-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-5,6-dimethyl-6-N-[(4-methylphenyl)methyl]-2-N-(2-morpholin-4-ylethyl)-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C24H32N6O4
    (6R)-5,6-dimethyl-6-N-[(4-methylphenyl)methyl]-2-N-(2-morpholin-4-ylethyl)-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-2-N-(3-phenylpropyl)-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C26H28FN5O3
    (6R)-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-2-N-(3-phenylpropyl)-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-6-N-benzyl-2-N-[2-(4-ethoxyphenyl)ethyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C27H31N5O4
    (6S)-6-N-benzyl-2-N-[2-(4-ethoxyphenyl)ethyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-6-N-benzyl-5,6-dimethyl-2-N-(2-morpholin-4-ylethyl)-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C23H30N6O4
    (6S)-6-N-benzyl-5,6-dimethyl-2-N-(2-morpholin-4-ylethyl)-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-5,6-dimethyl-6-N-(3-methylbutyl)-2-N-[(4-methylsulfanylphenyl)methyl]-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C23H31N5O3S
    (6S)-5,6-dimethyl-6-N-(3-methylbutyl)-2-N-[(4-methylsulfanylphenyl)methyl]-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-6-N-[(4-fluorophenyl)methyl]-2-N-[2-(furan-2-yl)ethyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C23H24FN5O4
    (6R)-6-N-[(4-fluorophenyl)methyl]-2-N-[2-(furan-2-yl)ethyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-5,6-dimethyl-N-(3-methylbutyl)-4-oxo-2-(piperidine-1-carbonyl)-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C20H31N5O3
    (6S)-5,6-dimethyl-N-(3-methylbutyl)-4-oxo-2-(piperidine-1-carbonyl)-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6S)-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-2-(piperidine-1-carbonyl)-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C22H26FN5O3
    (6S)-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-2-(piperidine-1-carbonyl)-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6S)-6-N-cyclopentyl-6-methyl-2-N-[2-(4-methylsulfanylphenyl)ethyl]-4-oxo-5-propyl-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C26H35N5O3S
    (6S)-6-N-cyclopentyl-6-methyl-2-N-[2-(4-methylsulfanylphenyl)ethyl]-4-oxo-5-propyl-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-2-N-(2-morpholin-4-ylethyl)-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C23H29FN6O4
    (6S)-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-2-N-(2-morpholin-4-ylethyl)-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-6-N-cyclopentyl-5-ethyl-6-methyl-2-N-[(4-methylphenyl)methyl]-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C24H31N5O3
    (6S)-6-N-cyclopentyl-5-ethyl-6-methyl-2-N-[(4-methylphenyl)methyl]-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-6-N-cyclopentyl-2-N-[2-(dimethylamino)ethyl]-6-methyl-4-oxo-5-propyl-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C21H34N6O3
    (6R)-6-N-cyclopentyl-2-N-[2-(dimethylamino)ethyl]-6-methyl-4-oxo-5-propyl-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-6-N-benzyl-2-N-[(3-chlorophenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C24H24ClN5O3
    (6R)-6-N-benzyl-2-N-[(3-chlorophenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-2-N-[2-(4-methylphenyl)ethyl]-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C26H28FN5O3
    (6R)-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-2-N-[2-(4-methylphenyl)ethyl]-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-2-N-cyclopentyl-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C22H26FN5O3
    (6S)-2-N-cyclopentyl-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-6-N-cyclopentyl-2-N-(3-methoxypropyl)-6-methyl-4-oxo-5-propyl-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C21H33N5O4
    (6S)-6-N-cyclopentyl-2-N-(3-methoxypropyl)-6-methyl-4-oxo-5-propyl-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide