去氢粗毛甘草素D | 517885-72-2

• 物质功能分类: 天然产物 - 黄酮类化合物
• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 异黄酮类化合物
• 中文名称: 去氢粗毛甘草素D
• 中文别名: 去氢粗毛甘草素 D
• 英文名称: Dehydroglyasperin D
• 英文别名: 4-[5,7-dimethoxy-6-(3-methylbut-2-enyl)-2H-chromen-3-yl]benzene-1,3-diol
• CAS: 517885-72-2
• 化学式: C₂₂H₂₄O₅
• 分子量: 368.4
• InChiKey: QHJJASRUTXHRAL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.6
• 重原子数：
  27
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  68.2
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR LIGANDS AND PROCESS FOR PRODUCING THE SAME
  申请人：KANEKA CORPORATION

  公开号：EP1440688A1

  公开（公告）日：2004-07-28

  The present invention easily and efficiently provides a peroxisome proliferator-activated receptor ligand, and a composition for amelioration of insulin resistance or for prevention and/or amelioration of the insulin resistance syndrome containing the same, as an active ingredient. The present invention relates to a peroxisome proliferator-activated receptor ligand which comprises a prenylflavonoid, a chalcone derivative exclusive of prenylflavonoids, a flavonol derivative exclusive of prenylflavonoids, and a salt, a glycoside and/or an esterified substance thereof acceptable as a pharmaceutical preparation or a food or a beverage; a composition containing the above ligand; a plant-derived extract containing the above ligand; and a process for producing the above extract.

  本发明简便高效地提供了一种过氧化物酶体增殖体激活受体配体，以及一种用于改善胰岛素抵抗或预防和/或改善胰岛素抵抗综合征的组合物，其中含有该配体作为活性成分。 本发明涉及一种过氧化物酶体增殖体激活受体配体，它包括一种前黄酮类化合物、一种不包括前黄酮类化合物的查尔酮衍生物、一种不包括前黄酮类化合物的黄酮醇衍生物，以及可作为药物制剂或食品或饮料的盐、苷和/或酯化物质；一种含有上述配体的组合物；一种含有上述配体的植物提取物；以及一种生产上述提取物的工艺。
• Peroxisome proliferator activated receptor ligands and process for producing the same
  申请人：Mae Tatsumasa

  公开号：US20050014819A1

  公开（公告）日：2005-01-20

  The present invention easily and efficiently provides a peroxisome proliferator-activated receptor ligand, and a composition for amelioration of insulin resistance or for prevention and/or amelioration of the insulin resistance syndrome containing the same, as an active ingredient. The present invention relates to a peroxisome proliferator-activated receptor ligand which comprises a prenylflavonoid, a chalcone derivative exclusive of prenyl flavonoids, a flavonol derivative exclusive of prenylflavonoids, and a salt, a glycoside and/or an esterified substance thereof acceptable as a pharmaceutical preparation or a food or a beverage; a composition containing the above ligand; a plant-derived extract containing the above ligand; and a process for producing the above extract.

  本发明简便高效地提供了一种过氧化物酶体增殖体激活受体配体，以及一种用于改善胰岛素抵抗或预防和/或改善胰岛素抵抗综合征的组合物，其中含有该配体作为活性成分。本发明涉及一种过氧化物酶体增殖体激活受体配体，它包括一种前酰基类黄酮、一种不包括前酰基类黄酮的查尔酮衍生物、一种不包括前酰基类黄酮的黄酮醇衍生物，以及可作为药物制剂或食品或饮料的盐、苷和/或酯化物质；一种含有上述配体的组合物；一种含有上述配体的植物提取物；以及一种生产上述提取物的工艺。
• PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR LIGAND AND PROCESS FOR PRODUCING THE SAME
  申请人：MAE Tatsumasa

  公开号：US20090036519A1

  公开（公告）日：2009-02-05

  The present invention easily and efficiently provides a peroxisome proliferator-activated receptor ligand, and a composition for amelioration of insulin resistance or for prevention and/or amelioration of the insulin resistance syndrome containing the same, as an active ingredient. The present invention relates to a peroxisome proliferator-activated receptor ligand which comprises a prenylflavonoid, a chalcone derivative exclusive of prenylflavonoids, a flavonol derivative exclusive of prenylflavonoids, and a salt, a glycoside and/or an esterified substance thereof acceptable as a pharmaceutical preparation or a food or a beverage; a composition containing the above ligand; a plant-derived extract containing the above ligand; and a process for producing the above extract.
• US7524975B2
  申请人：——

  公开号：US7524975B2

  公开（公告）日：2009-04-28
• US7888388B2
  申请人：——

  公开号：US7888388B2

  公开（公告）日：2011-02-15