山梨酸乙烯酯 | 42739-26-4

• 物质功能分类: 食品添加剂 - 防腐剂
• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 山梨酸乙烯酯
• 中文别名: 山梨酸乙烯酯(含对羟基苯甲醚阻聚剂)
• 英文名称: vinyl sorbate
• 英文别名: Sorbic acid vinyl ester；ethenyl (2E,4E)-hexa-2,4-dienoate
• CAS: 42739-26-4
• 化学式: C₈H₁₀O₂
• 分子量: 138.166
• InChiKey: ZHIUCPNDVATEDB-TWTPFVCWSA-N

物化性质

• 沸点：
  64 °C / 6mmHg
• 密度：
  0.96
• 闪点：
  77 °C
• 稳定性/保质期：
  常规情况下不会分解，也没有危险反应。

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  10
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

安全信息

• 海关编码：
  2916190090
• 储存条件：
  密封、阴凉、干燥保存。

SDS

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Section I.Chemical Product and Company Identification
Chemical Name Sorbic Acid Vinyl Ester
Portland OR
Synonym Vinyl Sorbate
Chemical Formula C8H10O2
42739-26-4
CAS Number

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Section II. Composition and Information on Ingredients
Toxicology Data
Chemical Name CAS Number Percent (%) TLV/PEL
Sorbic Acid Vinyl Ester 42739-26-4 Not available. Not available. Not available.

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Section III. Hazards Identification
Acute Health Effects No specific information is available in our data base regarding the toxic effects of this material for humans. However,
exposure to any chemical should be kept to a minimum. Skin and eye contact may result in irritation. May be harmful if
inhaled or ingested. Always follow safe industrial hygiene practices and wear proper protective equipment when handling
this compound.
Chronic Health Effects CARCINOGENIC EFFECTS : Not available.
MUTAGENIC EFFECTS : Not available.
TERATOGENIC EFFECTS : Not available.
Toxicity to the reproductive system: Not available.
There is no known effect from chronic exposure to this product. Repeated or prolonged exposure to this compound is not
known to aggravate existing medical conditions.

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Section IV. First Aid Measures
Check for and remove any contact lenses. DO NOT use an eye ointment. Flush eyes with running water for a minimum of 15
Eye Contact
minutes, occasionally lifting the upper and lower eyelids. Seek medical attention. Treat symptomatically and supportively.
If the chemical gets spilled on a clothed portion of the body, remove the contaminated clothes as quickly as possible,
Skin Contact
protecting your own hands and body. Place the victim under a deluge shower. If the chemical touches the victim's exposed
skin, such as the hands: Gently and thoroughly wash the contaminated skin with running water and non-abrasive soap. Be
particularly careful to clean folds, crevices, creases and groin. Cover the irritated skin with an emollient. Seek medical
attention. Treat symptomatically and supportively. Wash any contaminated clothing before reusing.
If the victim is not breathing, perform artificial respiration. Loosen tight clothing such as a collar, tie, belt or waistband. If
Inhalation
breathing is difficult, oxygen can be administered. Seek medical attention. Treat symptomatically and supportively.
Ingestion Remove dentures if any. Have conscious person drink several glasses of water or milk. INDUCE VOMITING by sticking
finger in throat. Lower the head so that the vomit will not reenter the mouth and throat. NEVER give an unconscious person
anything to ingest. Seek medical attention. Treat symptomatically and supportively.

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Section V. Fire and Explosion Data
Not available.
Flammability Combustible. Auto-Ignition
Flash Points 77°C (170.6°F) Flammable Limits Not available.
Combustion Products These products are toxic carbon oxides (CO, CO2).
Fire Hazards
No specific information is available regarding the flammability of this compound in the presence of various materials.
Explosion Hazards Risks of explosion of the product in presence of mechanical impact: Not available.
Risks of explosion of the product in presence of static discharge: Not available.
No additional information is available regarding the risks of explosion.
Fire Fighting Media SMALL FIRE: Use DRY chemicals, CO2, water spray or foam.
LARGE FIRE: Use water spray, fog or foam. DO NOT use water jet.
and Instructions
Continued on Next Page
Sorbic Acid Vinyl Ester

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Section VI. Accidental Release Measures
Spill Cleanup Combustible material.
Keep away from heat and sources of ignition. Mechanical exhaust required. Stop leak if without risk. Finish cleaning the spill
Instructions
by rinsing any contaminated surfaces with copious amounts of water.

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Section VII. Handling and Storage
Handling and Storage Keep away from heat and sources of ignition. Mechanical exhaust required. When not in use, tightly seal the container and
store in a dry, cool place. Avoid excessive heat and light. Do not breathe gas, fumes, vapor or spray. In case of insufficient
Information
ventilation, wear suitable respiratory equipment. If you feel unwell, seek medical attention and show the label when possible.
Treat symptomatically and supportively. Avoid contact with skin and eyes.
Always store away from incompatible compounds such as oxidizing agents.

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Section VIII. Exposure Controls/Personal Protection
Engineering Controls Provide exhaust ventilation or other engineering controls to keep the airborne concentrations of vapors below their respective
threshold limit value. Ensure that eyewash station and safety shower is proximal to the work-station location.
Personal Protection Splash goggles. Lab coat. Vapor respirator. Boots. Gloves. A MSHA/NIOSH approved respirator must be used to avoid
inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling this
product.
Exposure Limits Not available.

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Section IX. Physical and Chemical Properties
Physical state @ 20°C Liquid. Solubility Not available.
0.96 (water=1)
Specific Gravity
Molecular Weight 138.17 Partition Coefficient Not available.
Boiling Point Not available. Vapor Pressure Not available.
Melting Point Not available. Vapor Density Not available.
Not available. Not available.
Refractive Index Volatility
Critical Temperature Not available. Odor Not available.
Not available. Not available.
Viscosity Taste

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Section X. Stability and Reactivity Data
Stability

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This material is stable if stored under proper conditions. (See Section VII for instructions)
Avoid excessive heat and light.
Conditions of Instability
Incompatibilities Reactive with strong oxidizing agents.

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Section XI. Toxicological Information
RTECS Number Not available.
Ingestion. Inhalation.
Routes of Exposure
Toxicity Data Not available.
CARCINOGENIC EFFECTS : Not available.
Chronic Toxic Effects
MUTAGENIC EFFECTS : Not available.
TERATOGENIC EFFECTS : Not available.
Toxicity to the reproductive system: Not available.
There is no known effect from chronic exposure to this product. Repeated or prolonged exposure to this compound is not
known to aggravate existing medical conditions.
No specific information is available in our data base regarding the toxic effects of this material for humans. However,
Acute Toxic Effects
exposure to any chemical should be kept to a minimum. Skin and eye contact may result in irritation. May be harmful if
inhaled or ingested. Always follow safe industrial hygiene practices and wear proper protective equipment when handling this
compound.
Continued on Next Page
Sorbic Acid Vinyl Ester

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Section XII. Ecological Information
Ecotoxicity Not available.
Not available.
Environmental Fate

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Section XIII. Disposal Considerations
Recycle to process, if possible. Consult your local or regional authorities. You may be able to dissolve or mix material with a
Waste Disposal
combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber system. Observe all
federal, state, and local regulations when disposing of this substance.

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Section XIV. Transport Information
DOT Classification Not a DOT controlled material (United States).
NONE
PIN Number
Proper Shipping Name NONE
NONE
Packing Group (PG)
DOT Pictograms

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Section XV. Other Regulatory Information and Pictograms
TSCA Chemical Inventory This product is NOT on the EPA Toxic Substances Control Act (TSCA) inventory. The following notices are required by 40
CFR 720.36 (C) for those products not on the inventory list:
(EPA)
(i) These products are supplied solely for use in research and development by or under the supervision of a technically
qualified individual as defined in 40 CFR 720.0 et sec.
(ii) The health risks of these products have not been fully determined. Any information that is or becomes available will be
supplied on an MSDS sheet.
WHMIS Classification WHMIS CLASS B-3: Combustible liquid with a flash point between 37.8°C (100°F) and 93.3°C (200°F).
(Canada)
EINECS Number (EEC) Not available.
EEC Risk Statements Not available.

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SECTION 16 - ADDITIONAL INFORMATION
N/A

反应信息

• 作为反应物：
  描述：

  山梨酸乙烯酯 、 虎杖甙 在 Thermomyces lanuginosus lipase 作用下， 以 2-甲基四氢呋喃 为溶剂， 生成 6"-O-sorbyl-polydatin
  参考文献：
  名称：

  Highly efficient enzymatic synthesis of novel polydatin prodrugs with potential anticancer activity

  摘要：

  Efficient lipase-mediated research work was successfully exploited for synthesizing, potential 6 ''-O-acylpolydatin prodrugs in biomass-derived 2-methyltetrahydrofuran (2-MeTHF). The results of the enzyme recognitions of nine acyl donors evidently demonstrated that the position and number of the C-C double bond in acyl chains profoundly influenced the behavior of the enzyme, which could be attributable to the resonance effect between the double bond and carbonyl group. Further investigations showed that introducing various acyl groups into the polydatin apparently enhanced its pH stability and 1-octanol-water partition coefficient (log P). With regard to the human cervical cancer siHa cell apoptosis by a flow cytometry assay, the lipophilic 6 ''-O-sorboyl-polydatin exhibited improved apoptosis-inducing capability than the parent drug. The presence of the more lipophilic sorboyl chain in the acylated derivative could account for this. (C) 2016 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.procbio.2016.09.028
• 作为产物：
  描述：

  山梨酸 、 乙炔 在 三丁基膦 、 bis(η⁵-cyclooctadienyl)ruthenium 作用下， 以 甲苯 为溶剂， 反应 96.0h， 以67%的产率得到山梨酸乙烯酯
  参考文献：
  名称：

  Ruthenium-catalyzed selective addition of carboxylic acids to alkynes. A novel synthesis of enol esters

  摘要：

  DOI：

  10.1021/jo00387a024

文献信息

• [EN] PRODUCTION METHOD OF FLUOROETHERCARBOXYLIC ACID FLUORIDE AND FLUOROETHERCARBOXYLIC ACID<br/>[FR] PROCÉDÉ DE PRODUCTION DE FLUORURE D'ACIDE FLUOROÉTHERCARBOXYLIQUE ET D'ACIDE FLUOROÉTHERCARBOXYLIQUE
  申请人：DAIKIN IND LTD

  公开号：WO2010038902A1

  公开（公告）日：2010-04-08

  The present invention is a production method of a fluoroethercarboxylic acid fluoride, comprising the step of selectively producing a fluoroethercarboxylic acid fluoride represented by the formula (I): CF3O(CF(CF3)CF2O)CF(CF3)COF (I) by reacting hexafluoropropylene oxide with carbonyl fluoride in a solvent at a temperature of -30 to 40 °C in the presence of a catalyst, wherein the catalyst comprises at least one species selected from the group consisting of metal fluorides, tertiary amines, tertiary diamines and tetraalkylammonium salts, and the solvent is an aprotic polar solvent.

  本发明是一种氟醚羧酸氟的生产方法，包括以下步骤：在溶剂中，在催化剂的存在下，通过反应六氟丙烷氧化物和羰基氟，以选择性地生产由式(I)表示的氟醚羧酸氟：CF3O(CF(CF3)CF2O)CF(CF3)COF (I)。其中，催化剂包括金属氟化物、三级胺、三级二胺和四烷基铵盐中至少一种物种，溶剂为无水极性溶剂，反应温度在-30到40°C之间。
• Fluoroalkyl carboxylic acid derivative, method for producing fluorine-containing polymer, and aqueous dispersion of fluorine-containing polymer
  申请人：Morita Shigeru

  公开号：US20060281946A1

  公开（公告）日：2006-12-14

  This invention provides a novel compound which can be properly used as a surfactant, a method of producing a fluoropolymer, surfactant and a fluoropolymer aqueous dispersions using the novel compound. This invention is a fluoroalkylcarboxylic acid derivative which is represented by the general formula (i): Rf 1 (OCH 2 CF 2 CF 2 ) n1 OCX 1 X 2 CF 2 (Rf 2 ) n2 COOM   (i) wherein Rf 1 represents a straight or branched fluoroalkyl group containing 1 to 20 carbon atoms, which fluoroalkyl group may optionally contain 1 to 5 oxygen atoms in the principal chain thereof, Rf 2 represents a straight or branched fluoroalkylene group containing 1 to 25 carbon atoms, said fluoroalkylene group may optionally contain 1 to 5 oxygen atoms in the principal chain thereof, n1 represents an integer of 0 to 3, n2 represents an integer of 0 or 1, X 1 and X 2 are the same or different and each represents hydrogen atom or fluorine atom, and M represents NH 4 or a monovalent metal element.

  该发明提供了一种新型化合物，可适当用作表面活性剂，一种生产氟聚合物的方法，使用该新型化合物制备表面活性剂和氟聚合物水分散液。该发明是一种氟烷基羧酸衍生物，由通式（i）表示：Rf1（OCH2CF2CF2）n1OCX1X2CF2（Rf2）n2COOM   （i）其中，Rf1表示含有1到20个碳原子的直链或支链氟烷基，该氟烷基在其主链中可以选择性地含有1到5个氧原子，Rf2表示含有1到25个碳原子的直链或支链氟烷基，该氟烷基在其主链中可以选择性地含有1到5个氧原子，n1表示0到3的整数，n2表示0或1的整数，X1和X2相同或不同，每个表示氢原子或氟原子，M表示NH4或一价金属元素。
• Liquid crystalline compound, liquid crystal composition and their polymers
  申请人：Sasada Yasuyuki

  公开号：US20050007541A1

  公开（公告）日：2005-01-13

  The present invention provides a compound represented by formula (1) defined in the specification and a liquid crystal composition comprising the compound. The invention further provides a polymer obtained by polymerization of compound or composition above, and further the present invention provides a film, an optical anisotropic material, A ¼ or ½ wavelength functional plate, an optical compensation element, an optical element and a liquid crystal display element employing the polymer.

  本发明提供了一种由规范中定义的式（1）所代表的化合物以及包括该化合物的液晶组合物。本发明还提供了通过聚合上述化合物或组合物获得的聚合物，此外，本发明还提供了一种薄膜，一种光学各向异性材料，1/4或1/2波长功能板，光学补偿元件，光学元件和采用该聚合物的液晶显示元件。
• Cellulose ester film, cellulose ester dope, protective film of polarizing plate and polarizing plate
  申请人：Konica Corporation.

  公开号：US20020102369A1

  公开（公告）日：2002-08-01

  Disclosed is a cellulose ester film comprising a polymer prepared by polymerizing at least one ethylenically unsaturated monomer selected from vinyl esters, vinyl esters having a functional group, acrylic esters, and acrylic esters having a functional group, wherein the polymer has a weight average molecular weight of not more than 5,000.

  本发明公开了一种纤维素酯膜，其包括通过聚合至少一种乙烯基不饱和单体而制备的聚合物，所述乙烯基不饱和单体包括乙烯酸酯、具有功能基的乙烯酸酯、丙烯酸酯和具有功能基的丙烯酸酯，其中所述聚合物的重均分子量不超过5,000。
• Medical Resin Composition, Process For Producing Resin Composition and Process For Producing Molded Article
  申请人：Tanaka Jiro

  公开号：US20080200630A1

  公开（公告）日：2008-08-21

  A medical resin composition is produced by mixing a powder of a polymer (A) comprising repeating units having an ester group and a liquid of a vinyl ester monomer (B) having 6 or more carbon atoms to increase a viscosity and, according to demand, further performing a polymerization reaction. The thus produced resin composition inhibits leaching of irritative substances, reduces any adverse effects on the human body by endocrine disruptors, etc. and can be prepared with high operational efficiency. The resin composition is suitably used as a dental resin composition such as a tissue conditioner, a functional impression material, a lining material, a denture base material or a mouth piece material.

  一种医用树脂组合物的制备方法，包括将含有酯基重复单元的聚合物(A)粉末和含有6个或更多碳原子的乙烯酸酯单体(B)液体混合以增加粘度，并根据需要进一步进行聚合反应。由此制得的树脂组合物抑制刺激性物质的渗出，减少内分泌干扰物对人体的不良影响等，并且可以高效制备。该树脂组合物适用于牙科树脂组合物，例如组织调整剂、功能印模材料、填补材料、义齿基材料或口腔器材材料。

表征谱图