申请人:RNS CO.,LTD.
公开号:US20150283051A1
公开(公告)日:2015-10-08
Provided is a skin whitening composition with excellent whitening effects, specifically, a derivative or a polyhydroxy cyclic compound represented by Formula I or a pharmacologically acceptable salt thereof, comprising;
wherein
is derived from an aromatic cyclic compound, C
n
, C
n+1
and C
n+2
are three neighboring carbon atoms present in the aromatic cyclic compound, wherein n is a positive integer, R
1
and R
2
are each a saturated or unsaturated straight or branched alkyl or acyl group having 3 to 12 carbon atoms, and R
3
, R
4
, R
5
and R
6
are each independently at least one substituent selected from hydrogen, alkyl, alkoxy, acyloxy, acyloxymethyl, oxo, hydroxy, vinyl, nitrile, carboxaldehyde, carbonitrile and aldehyde.
提供一个具有优异美白效果的皮肤美白组合物,具体为公式I所表示的衍生物或多元醇环化合物或其药理上可接受的盐,其中
所述的芳香族环化合物,C
n
,C
n+1
和C
n+2
是存在于芳香族环化合物中的三个相邻的碳原子,其中n是正整数,R
1
和R
2
分别是具有3至12个碳原子的饱和或不饱和直链或支链烷基或酰基,而R
3
,R
4
,R
5
和R
6
各自独立地选自氢、烷基、烷氧基、酰氧基、酰氧甲基、氧代、羟基、乙烯基、腈、羧醛、碳腈和醛中至少一个取代基。