3,4,6-tri-O-acetyl-2-deoxy-2-N-phthalimido-β-D-glucopyranosyl azide | 102816-24-0
中文名称
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中文别名
——
英文名称
3,4,6-tri-O-acetyl-2-deoxy-2-N-phthalimido-β-D-glucopyranosyl azide
英文别名
3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-1-β-D-glucopyranosyl azide；3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl azide；3,4,6-Tri-O-acetyl-2-deoxy-2-phthalimido-beta-D-glucopyranosyl azide；[(2R,3S,4R,5R,6R)-3,4-diacetyloxy-6-azido-5-(1,3-dioxoisoindol-2-yl)oxan-2-yl]methyl acetate
CAS
102816-24-0
化学式
C20H20N4O9
mdl
——
分子量
460.4
InChiKey
UJSZDYIUFXNQKN-DUQPFJRNSA-N
BEILSTEIN
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EINECS
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物化性质
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计算性质
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ADMET
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安全信息
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SDS
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制备方法与用途
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上下游信息
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文献信息
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表征谱图
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同类化合物
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相关功能分类
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相关结构分类
物化性质
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熔点：135-137 °C
计算性质
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辛醇/水分配系数(LogP)：1.5
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重原子数：33
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可旋转键数：9
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环数：3.0
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sp3杂化的碳原子比例：0.45
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拓扑面积：140
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氢给体数：0
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氢受体数：11
上下游信息
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上游原料
中文名称 英文名称 CAS号 化学式 分子量 2-脱氧-2-苯二酰亚胺-1,3,4,6-四-氧-乙酰-β-D-吡喃葡萄糖 1,3,4,6-tetra-O-acetyl-2-deoxy-2-phthalimido-β-D-glucopyranose 10022-13-6 C22H23NO11 477.425 —— 2-deoxy-2-phthalimido-β-D-glucopyranose 31505-45-0 C14H15NO7 309.276 -
下游产品
中文名称 英文名称 CAS号 化学式 分子量 —— 3,4,6-tri-O-acetyl-1-amino-2-deoxy-2-N-phthalimido-β-D-glucopyranose 191038-68-3 C20H22N2O9 434.403 —— 2-deoxy-2-phthalimido-β-D-glucopyranosyl azide 102816-23-9 C14H14N4O6 334.288 —— [(2R,3S,4R,5R,6S)-4-acetyloxy-6-[(2R,3S,4R,5R,6R)-6-azido-5-(1,3-dioxoisoindol-2-yl)-4-hydroxy-2-[(4-methoxyphenyl)methoxymethyl]oxan-3-yl]oxy-5-(1,3-dioxoisoindol-2-yl)-2-(phenylmethoxymethyl)oxan-3-yl] acetate 449177-43-9 C47H45N5O15 919.899 —— 3,6-di-O-benzyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl azide 161315-66-8 C28H26N4O6 514.538 —— 3-O-benzyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl azide 218961-14-9 C21H20N4O6 424.413 —— 4,6-O-benzylidene-3-O-benzyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl azide 191037-60-2 C28H24N4O6 512.522 —— 6-O-p-methoxybenzyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl azide 449177-35-9 C22H22N4O7 454.439 —— 4,6-O-benzylidene-2-deoxy-2-phthalimido-β-D-glucopyranosyl azide 191037-58-8 C21H18N4O6 422.397 —— 3-hexadecyloxy-1-N-(3,4,6-tri-O-acetyl-2-deoxy-2-N-phthalimido-β-D-glucopyranosyl)propanamide 1585996-98-0 C39H58N2O11 730.896 —— 6-O-benzyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl-(1->4)-6-O-p-methoxybenzyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl azide 449177-45-1 C43H41N5O13 835.824 —— O-(2,3,4-tri-O-benzyl-α-D-fucopyranosyl)-(1->6)-3-O-benzyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl azide 218961-16-1 C48H48N4O10 840.93 —— 2-[(2R,4aR,6R,7R,8R,8aS)-6-Azido-8-hydroxy-2-(4-methoxy-phenyl)-hexahydro-pyrano[3,2-d][1,3]dioxin-7-yl]-isoindole-1,3-dione 449177-33-7 C22H20N4O7 452.423 —— 3-O-benzyl-2-deoxy-6-O-(p-methoxyphenyl)-2-phthalimido-β-D-glucopyranosyl azide 182923-92-8 C28H26N4O7 530.537 —— 3,6-di-O-benzyl-4-O-(chloroacetyl)-2-deoxy-2-phthalimido-β-D-glucopyranosyl-(1→4)-3-O-benzyl-2-deoxy-6-O-(p-methoxyphenyl)-2-phthalimido-β-D-glucopyranosyl azide 182923-95-1 C58H52ClN5O14 1078.53 —— 3,6-di-O-benzyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl-(1→4)-3-O-benzyl-2-deoxy-6-O-(p-methoxyphenyl)-2-phthalimido-β-D-glucopyranosyl azide 182923-98-4 C56H51N5O13 1002.05 —— N-(2-deoxy-2-phthalimido-3,4,6-tri-O-acetyl-β-D-glucopyranosyl)-thiophene-2-carboxamide 904693-75-0 C25H24N2O10S 544.539 —— heptadecylfluoro-1-N-(3,4,6-tri-O-acetyl-2-deoxy-2-N-phthalimido-β-D-glucopyranosyl)undecanamide 1585996-99-1 C31H25F17N2O10 908.52 —— 3-O-benzyl-4,6-O-benzylidene-2-p-nitrobenzoyl-β-D-glucopyranosyl-(1->4)-6-O-benzyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl-(1->4)-6-O-p-methoxybenzyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl azide 449177-47-3 C70H64N6O21 1325.31 —— O-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-(1*4)-6-O-tert-butyldiphenylsilyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl azide 543719-74-0 C44H50N4O15Si 902.984 —— 6-O-tert-butyldiphenylsilyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl azide 543719-73-9 C30H32N4O6Si 572.693 —— 4-(hexadecyloxy)methyl-1-(3,4,6-tri-O-acetyl-2'-deoxy-2'-N-phthalimido-β-D-glucopyranosyl)-1,2,3-triazole 1585997-00-7 C39H56N4O10 740.894 —— 2-acetamido-2-deoxy-3,4,6-tri-O-acetyl-β-D-glucopyranosyl-(1-4)-2-acetamido-2-deoxy-3,6-di-O-acetyl-β-D-glucopyranosyl azide 29625-70-5 C26H37N5O15 659.604 —— 1-(2′-deoxy-2′-phthalimido-3′,4′,6′-tri-O-acetyl-β-D-glucopyranosyl)-4-phenyl-1,2,3-triazole 1361485-97-3 C28H26N4O9 562.536 —— 1-(2′-deoxy-2′-phthalimido-3,4,6-tri-O-acetyl-β-D-glucopyranosyl)-4-(2-naphthyl)-1,2,3-triazole 1361485-98-4 C32H28N4O9 612.596 - 1
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反应信息
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作为反应物：描述：3,4,6-tri-O-acetyl-2-deoxy-2-N-phthalimido-β-D-glucopyranosyl azide 在 2,6-二甲基吡啶 、 N-碘代丁二酰亚胺 、 三氟甲磺酸 、 水 、 sodium 、 甲基三辛基氯化铵 、 sodium hydride 、 对甲苯磺酸 、 sodium hydroxide 作用下， 以 甲醇 、 二氯甲烷 、 水 、 N,N-二甲基甲酰胺 、 乙腈 、 mineral oil 为溶剂， 反应 14.75h， 生成 3,6-di-O-benzyl-4-O-(chloroacetyl)-2-deoxy-2-phthalimido-β-D-glucopyranosyl-(1→4)-3-O-benzyl-2-deoxy-6-