牡荆内酯 | 61263-49-8

• 物质功能分类: 天然产物 - 萜类
• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 中文名称: 牡荆内酯
• 英文名称: Vitexilactone
• 英文别名: [(1R,3R,4R,4aS,8aS)-4-hydroxy-3,4a,8,8-tetramethyl-4-[2-(5-oxo-2H-furan-3-yl)ethyl]-2,3,5,6,7,8a-hexahydro-1H-naphthalen-1-yl] acetate
• CAS: 61263-49-8
• 化学式: C₂₂H₃₄O₅
• 分子量: 378.5
• InChiKey: FBWWXAGANVJTLU-HEXLTJKYSA-N

物化性质

• 熔点：
  148～149℃
• 沸点：
  501.5±40.0 °C(Predicted)
• 密度：
  1.13±0.1 g/cm3(Predicted)
• 溶解度：
  溶于氯仿、二氯甲烷、乙酸乙酯、DMSO、丙酮等。

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  27
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.82
• 拓扑面积：
  72.8
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• Agent for lowering prolactin
  申请人：——

  公开号：US20040138297A1

  公开（公告）日：2004-07-15

  The present invention relates to a prolactin lowering drug containing at least one bicyclic diterpene of the labdane type. 1 wherein R1=H, C 1 to C 3 alkyl or C 1 to C 3 acyl.

  本发明涉及一种降低催乳素的药物，其中至少含有一种拉布烷类双环二萜。 1 其中 R1=H, C 1 至 C 3 烷基或 C 1 至 C 3 酰基。
• Coated vaginal devices for vaginal delivery of therapeutically effective and/or health-promoting agents
  申请人：Wilson Michelle

  公开号：US20050276836A1

  公开（公告）日：2005-12-15

  A vaginal device for delivering therapeutical and/or health-promoting agents. The vaginal device partly or completely coated by, covered by or combined with a coating or covering comprising a film, foam, strip, cap, cup or particles. The coating of the device comprises a mucoadhesive composition comprising a therapeutical and/or health-promoting agent.

  一种用于输送治疗和/或促进健康药物的阴道装置。该阴道装置部分或全部由薄膜、泡沫、条、盖、杯或颗粒组成的涂层或覆盖物涂覆、覆盖或结合。该装置的涂层包括一种粘液粘合剂组合物，其中含有治疗剂和/或促进健康剂。
• COATED VAGINAL DEVICES FOR VAGINAL DELIVERY OF THERAPEUTICALLY EFFECTIVE AND/ OR HEALTH-PROMOTING AGENTS
  申请人：UMD, Inc.

  公开号：EP1776071A2

  公开（公告）日：2007-04-25
• Compositions and Methods Comprising Zingiber Species
  申请人：Li Dan

  公开号：US20080160116A1

  公开（公告）日：2008-07-03

  An aspect of the present invention relates to compositions comprising a gingerol, for example, compositions comprising gingerol in an amount greater than about 2% by weight. In some aspects of the invention, the composition comprises 6-gingerol, 8-gingerol, 10-gingerol, 6-shagaol, or combinations thereof. Another aspect of the invention relates to a method for extracting a ginger species comprising, sequentially extracting a ginger species plant material to yield an essential oil fraction, a gingerol fraction, a phenolic fraction, and a polysaccharide fraction, wherein the essential oil and gingerol fractions are derived by extracting plant feedstock material by supercritical carbon dioxide extraction, the phenolic fraction is extracted from the plant feedstock material or from the remainder of the essential oil and gingerol extractions by hydroalcoholic extraction, and the polysaccharide fraction is derived by water extraction of the remainder of the phenolic extraction.
• US6635672B1
  申请人：——

  公开号：US6635672B1

  公开（公告）日：2003-10-21