(1S,3R,5S,7S,8S,10R,12S,13S,15S,18S,20R,21R,24R)-21-[tert-butyl(dimethyl)silyl]oxy-8-[3-[tert-butyl(diphenyl)silyl]oxypropyl]-15-ethylsulfanyl-7,10,21-trimethyl-20-(3-phenylmethoxypropyl)-4,9,14,19,25-pentaoxapentacyclo[13.10.0.03,13.05,10.018,24]pentacosan-12-ol | 908866-26-2

分子结构分类

有机化合物 - 苯类化合物 - 苯和取代衍生物

中文名称

——

中文别名

——

英文名称

(1S,3R,5S,7S,8S,10R,12S,13S,15S,18S,20R,21R,24R)-21-[tert-butyl(dimethyl)silyl]oxy-8-[3-[tert-butyl(diphenyl)silyl]oxypropyl]-15-ethylsulfanyl-7,10,21-trimethyl-20-(3-phenylmethoxypropyl)-4,9,14,19,25-pentaoxapentacyclo[13.10.0.03,13.05,10.018,24]pentacosan-12-ol

英文别名

——

(1S,3R,5S,7S,8S,10R,12S,13S,15S,18S,20R,21R,24R)-21-[tert-butyl(dimethyl)silyl]oxy-8-[3-[tert-butyl(diphenyl)silyl]oxypropyl]-15-ethylsulfanyl-7,10,21-trimethyl-20-(3-phenylmethoxypropyl)-4,9,14,19,25-pentaoxapentacyclo[13.10.0.03,13.05,10.018,24]pentacosan-12-ol化学式

CAS

908866-26-2

化学式

C₆₀H₉₂O₉SSi₂

mdl

——

分子量

1045.62

InChiKey

OEMGXOWHSNKOPV-ZEEJJHQYSA-N

BEILSTEIN

——

EINECS

——

计算性质

辛醇/水分配系数(LogP)：

12.16
重原子数：

72
可旋转键数：

19
环数：

8.0
sp3杂化的碳原子比例：

0.7
拓扑面积：

119
氢给体数：

1
氢受体数：

10

上下游信息

上游原料

中文名称	英文名称	CAS号	化学式	分子量
——	(2S,3S,4aS,6R,7S,8S,9aR)-6-[[(1R,3S,4R,7S,9R,10R)-10-[tert-butyl(dimethyl)silyl]oxy-4-[(4-methoxyphenyl)methoxy]-10-methyl-9-(3-phenylmethoxypropyl)-2,8-dioxabicyclo[5.5.0]dodecan-3-yl]methyl]-2-[3-[tert-butyl(diphenyl)silyl]oxypropyl]-3,9a-dimethyl-2,3,4,4a,6,7,8,9-octahydropyrano[3,2-b]oxepine-7,8-diol	908866-24-0	C₆₆H₉₈O₁₁Si₂	1123.67
——	(2S,3S,4aS,6R,8S,9aR)-6-[[(1R,3S,4R,7S,9R,10R)-10-[tert-butyl(dimethyl)silyl]oxy-4-[(4-methoxyphenyl)methoxy]-10-methyl-9-(3-phenylmethoxypropyl)-2,8-dioxabicyclo[5.5.0]dodecan-3-yl]methyl]-2-[3-[tert-butyl(diphenyl)silyl]oxypropyl]-8-hydroxy-3,9a-dimethyl-2,3,4,4a,8,9-hexahydropyrano[3,2-b]oxepin-7-one	908866-23-9	C₆₆H₉₆O₁₁Si₂	1121.65
——	(2S,3S,4aS,6R,9aR)-6-[[(1R,3S,4R,7S,9R,10R)-10-[tert-butyl(dimethyl)silyl]oxy-4-[(4-methoxyphenyl)methoxy]-10-methyl-9-(3-phenylmethoxypropyl)-2,8-dioxabicyclo[5.5.0]dodecan-3-yl]methyl]-2-[3-[tert-butyl(diphenyl)silyl]oxypropyl]-3,9a-dimethyl-2,3,4,4a,8,9-hexahydropyrano[3,2-b]oxepin-7-one	908866-22-8	C₆₆H₉₆O₁₀Si₂	1105.65
——	3-[(2S,3S,4aS,9aR)-6-[[(1R,3S,4R,7S,9R,10R)-10-[tert-butyl(dimethyl)silyl]oxy-4-[(4-methoxyphenyl)methoxy]-10-methyl-9-(3-phenylmethoxypropyl)-2,8-dioxabicyclo[5.5.0]dodecan-3-yl]methyl]-3,9a-dimethyl-2,3,4,4a,8,9-hexahydropyrano[3,2-b]oxepin-2-yl]propoxy-tert-butyl-diphenylsilane	924656-32-6	C₆₆H₉₆O₉Si₂	1089.65
——	[(2S,3S,4aS,9aR)-2-[3-[tert-butyl(diphenyl)silyl]oxypropyl]-3,9a-dimethyl-2,3,4,4a,8,9-hexahydropyrano[3,2-b]oxepin-6-yl] diphenyl phosphate	908865-85-0	C₄₂H₅₁O₇PSi	726.922
——	(2S,3S)-6-[tert-butyl(diphenyl)silyl]oxy-3-[(4-methoxyphenyl)methoxy]-2-methylhexan-1-ol	908865-92-9	C₃₁H₄₂O₄Si	506.758
——	tert-butyl-[[(1S,3R,4R,7R,10R)-10-[(4-methoxyphenyl)methoxy]-4-methyl-9-methylidene-3-(3-phenylmethoxypropyl)-2,8-dioxabicyclo[5.5.0]dodecan-4-yl]oxy]-dimethylsilane	908865-86-1	C₃₆H₅₄O₆Si	610.907

下游产品

中文名称	英文名称	CAS号	化学式	分子量
——	3-[(1S,3R,5S,7S,8S,10R,12S,13R,15S,18S,20R,21R,24R)-12,21-bis[[tert-butyl(dimethyl)silyl]oxy]-15-ethylsulfanyl-7,10,21-trimethyl-20-(3-phenylmethoxypropyl)-4,9,14,19,25-pentaoxapentacyclo[13.10.0.03,13.05,10.018,24]pentacosan-8-yl]propoxy-tert-butyl-diphenylsilane	908866-27-3	C₆₆H₁₀₆O₉SSi₃	1159.88
——	3-[(1S,3R,5S,7S,8S,10R,12S,13R,15R,18S,20R,21R,24R)-12,21-bis[[tert-butyl(dimethyl)silyl]oxy]-7,10,15,21-tetramethyl-20-(3-phenylmethoxypropyl)-4,9,14,19,25-pentaoxapentacyclo[13.10.0.03,13.05,10.018,24]pentacosan-8-yl]propoxy-tert-butyl-diphenylsilane	908866-28-4	C₆₅H₁₀₄O₉Si₃	1113.79
——	3-[(1S,3R,5S,7S,8S,10R,12S,13R,15R,18S,20R,21R,24R)-12,21-bis[[tert-butyl(dimethyl)silyl]oxy]-20-[3-[tert-butyl(dimethyl)silyl]oxypropyl]-7,10,15,21-tetramethyl-4,9,14,19,25-pentaoxapentacyclo[13.10.0.03,13.05,10.018,24]pentacosan-8-yl]propoxy-tert-butyl-diphenylsilane	908866-29-5	C₆₄H₁₁₂O₉Si₄	1137.93
——	3-[(1S,3R,5S,7S,8S,10R,12S,13R,15R,18S,20R,21R,24R)-8-[(3E,5E)-7-[tert-butyl(diphenyl)silyl]oxy-4,5-dimethylhepta-3,5-dienyl]-7,10,15,21-tetramethyl-12,21-bis(triethylsilyloxy)-4,9,14,19,25-pentaoxapentacyclo[13.10.0.03,13.05,10.018,24]pentacosan-20-yl]propan-1-ol	908866-35-3	C₆₄H₁₀₆O₉Si₃	1103.8

反应信息

作为反应物：

描述：

(1S,3R,5S,7S,8S,10R,12S,13S,15S,18S,20R,21R,24R)-21-[tert-butyl(dimethyl)silyl]oxy-8-[3-[tert-butyl(diphenyl)silyl]oxypropyl]-15-ethylsulfanyl-7,10,21-trimethyl-20-(3-phenylmethoxypropyl)-4,9,14,19,25-pentaoxapentacyclo[13.10.0.03,13.05,10.018,24]pentacosan-12-ol 在 tris(dibenzylideneacetone)dipalladium (0) 、三苯胂咪唑、甲醇、 N-碘代丁二酰亚胺、正丁基锂、噻吩-2-甲酸亚铜(I) 、 LiDBB 、 pyridine-SO3 complex 、四丁基氟化铵、三(二甲氨基)锍二氟三甲基硅酸、双氧水、 4-甲基苯磺酸吡啶、碳酸氢钠、 potassium carbonate 、戴斯-马丁氧化剂、氟化氢吡啶、溶剂黄146 、三乙胺、间氯过氧苯甲酸作用下，以四氢呋喃、甲醇、六甲基磷酰三胺、正己烷、二氯甲烷、水、二甲基亚砜、 N,N-二甲基甲酰胺、