非甾抗炎药
非甾体类抗炎药依据化学结构可分为水杨酸类、丙酸类、乙酸类、灭酸类和烯酸类，它们主要通过抑制环氧合酶（COX），阻断花生四烯酸向前列腺素的转化，从而发挥解热、镇痛和抗炎作用。人体内存在两种环氧合酶：COX-1 和 COX-2。COX-1 主要分布在胃肠道、肾脏和血小板等组织中，抑制后可能引起胃肠道损伤等不良反应；而 COX-2 主要在炎症组织中分布，是一种诱导性酶，在炎症过程中发挥重要作用。
| 中文名称 | 英文名称 | CAS号 | 化学式 | 结构式图片 |
|---|---|---|---|---|
| 非诺洛芬钙盐二水合物 | Fenoprofen calcium salt hydrate | 71720-56-4 | C15H16CaO4 |
|
| 非普拉宗 | feprazone | 30748-29-9 | C20H20N2O2 |
|
| 阿西美辛 | acemetacin | 53164-05-9 | C21H18ClNO6 |
|
| 阿明洛芬 | alminoprofen | 39718-89-3 | C13H17NO2 |
|
| 醋氯芬酸 | aceclofenac | 89796-99-6 | C16H13Cl2NO4 |
|
| 酮基布洛芬 | ketoprofen | 22071-15-4 | C16H14O3 |
|
| 酮咯酸 | Ketorolac | 74103-06-3 | C15H13NO3 |
|
| 西萘普生 | Cinaproxen | 89163-44-0 | C19H21NO5S |
|
| 萘普生钠 | (2S)-2-(6-Methoxynaphthalen-2-YL)propanoic acid sodium | 26159-34-2 | C14H14NaO3 |
|
| 萘普生 | (2S)-2-(6-methoxy(2-naphthyl))propanoic acid | 22204-53-1 | C14H14O3 |
|
| 萘丁美酮 | nabumetone | 42924-53-8 | C15H16O2 |
|
| 苯氯布宗 | 4-butyl-4-(4-chloro-benzoyloxymethyl)-1,2-diphenyl-pyrazolidine-3,5-dione | 23111-34-4 | C27H25ClN2O4 |
|
| 苄达酸 | bendazac | 20187-55-7 | C16H14N2O3 |
|
| 苄达明 | benzydamine | 642-72-8 | C19H23N3O |
|
| 芬布芬 | 3-(p-phenyl)benzoylpropionic acid | 36330-85-5 | C16H14O3 |
|
| 艾氟洛芬 | (S)-(+)-flurbiprofen | 51543-39-6 | C15H13FO2 |
|
| 艾拉莫德 | Iguratimod | 123663-49-0 | C17H14N2O6S |
|
| 舒洛芬 | 2-[4-(thien-2-ylcarbonyl)phenyl]propanoic acid | 40828-46-4 | C14H12O3S |
|
| 羟保松 | OXYPHENBUTAZONE | 129-20-4 | C19H20N2O3 |
|
| 美索巴莫 | methocarbamol | 532-03-6 | C11H15NO5 |
|
| 美洛昔康 | meloxicam | 71125-38-7 | C14H13N3O4S2 |
|
| 罗非昔布 | rofecoxib | 162011-90-7 | C17H14O4S |
|
| 盐酸苄达明 | benzydamine hydrochloride | 132-69-4 | C19H23N3O*ClH |
|
| 痛灭定钠 | Sodium 1-methyl-5-(p-toluoyl)-pyrrole-2-acetic acid | 35711-34-3 | C15H15NNaO3 |
|
| 甲氯芬那酸 | MECLOFENAMIC ACID | 644-62-2 | C14H11Cl2NO2 |
|
| 甲氯灭酸钠 | 2-[(2,6-Dichloro-3-methylphenyl)amino]benzoic acid sodium salt monohydrate | 6385-02-0 | C14H11Cl2NNaO2 |
|
| 洛索洛芬钠 | 80382-23-6 | C15H18NaO3 |
|
|
| 洛索洛芬 | loxoprofen | 68767-14-6 | C15H18O3 |
|
| 泊米布洛芬 | 2-(5h-[1]benzopyrano[2,3-b]pyridin-7-yl)propionic acid | 52549-17-4 | C15H13NO3 |
|
| 氯诺昔康 | lornoxicam | 70374-39-9 | C13H10ClN3O4S2 |
|
| 氯苯扎利 | lobenzarit | 63329-53-3 | C14H10ClNO4 |
|
| 氯灭酸 | N-(3-chlorophenyl)anthranilic acid | 13278-36-9 | C13H10ClNO2 |
|
| 氟诺洛芬 | Flunoxaprofen | 66934-18-7 | C16H12FNO3 |
|
| 氟苯柳 | FLUFENISAL | 22494-27-5 | C15H11FO4 |
|
| 氟苯尼考 | Florfenicol | 73231-34-2 | C12H14Cl2FNO4S |
|
| 氟胺烟酸葡甲胺盐 | flunixin Meglumine | 42461-84-7 | C7H17NO5*C14H11F3N2O2 |
|
| 氟瑞托芬 | 4-(2-fluorophenyl)-1-ethynylbenzene | 56917-29-4 | C14H9F |
|
| 氟灭酸 | flufenamic acid | 530-78-9 | C14H10F3NO2 |
|
| 氟比洛芬酯 | fluorbiprofen axetil | 91503-79-6 | C19H19FO4 |
|
| 氟比洛芬 | fluorobiprofen | 5104-49-4 | C15H13FO2 |
|
| 氟替阿嗪 | 8-trifluoromethyl-10<i>H</i>-phenothiazine-1-carboxylic acid | 7220-56-6 | C14H8F3NO2S |
|
| 氟尼酸 | Niflumic Acid | 4394-00-7 | C13H9F3N2O2 |
|
| 桂美辛 | Cinmethacin | 20168-99-4 | C21H19NO4 |
|
| 来氟米特 | Leflunomide | 75706-12-6 | C12H9F3N2O2 |
|
| 替诺立定 | tinoridine | 24237-54-5 | C17H20N2O2S |
|
| 替诺昔康 | tenoxicam | 59804-37-4 | C13H11N3O4S2 |
|
| 托灭酸 | tolfenamic Acid | 13710-19-5 | C14H12ClNO2 |
|
| 扑湿痛 | mefenamic Acid | 61-68-7 | C15H15NO2 |
|
| 帕瑞昔布钠 | Propanamide, N-[[4-(5-methyl-3-phenyl-4-isoxazolyl)phenyl]sulfonyl]-, sodium salt (1:1) | 198470-85-8 | C19H18N2NaO4S |
|
| 布溪那明 | bucillamine | 65002-17-7 | C7H13NO3S2 |
|
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