2,2,5,5-四(羟基甲基)环戊酮 | 3322-70-1

• 物质功能分类: 有机原料 - 酮类化合物
• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 2,2,5,5-四(羟基甲基)环戊酮
• 英文名称: 2,2,5,5-tetra(hydroxymethyl)-cyclopentanone
• 英文别名: 2,2,5,5-Tetramethylolcyclopentanon；2,2,5,5-Tetrakis(hydroxymethyl)cyclopentan-1-one
• CAS: 3322-70-1
• 化学式: C₉H₁₆O₅
• mdl: MFCD00223933
• 分子量: 204.223
• InChiKey: ZMFZVJRDJVDKQN-UHFFFAOYSA-N

物化性质

• 熔点：
  142-144 °C
• 稳定性/保质期：
  避免与不相容的材料、湿空气或水接触。

计算性质

• 辛醇/水分配系数(LogP)：
  -2.1
• 重原子数：
  14
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.888
• 拓扑面积：
  98
• 氢给体数：
  4
• 氢受体数：
  5

安全信息

• 危险品标志：
  Xi
• 危险类别码：
  R36/37/38
• 海关编码：
  2914400090
• 安全说明：
  S26,S37/39

SDS

Name:	2 2 5 5-Tetrakis(hydroxymethyl)cyclopentanone Material Safety Data Sheet
Synonym:
CAS:	3322-70-1

Section 1 - Chemical Product MSDS Name:2 2 5 5-Tetrakis(hydroxymethyl)cyclopentanone Material Safety Data Sheet
Synonym:

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Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS

CAS#	Chemical Name	content	EINECS#
3322-70-1	2,2,5,5-Tetrakis(hydroxymethyl)cyclope		unlisted

Hazard Symbols: XI
Risk Phrases: 36/37/38

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Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Irritating to eyes, respiratory system and skin.
Potential Health Effects
Eye:
Causes eye irritation.
Skin:
Causes skin irritation. May be harmful if absorbed through the skin.
Ingestion:
May cause irritation of the digestive tract. May be harmful if swallowed.
Inhalation:
Causes respiratory tract irritation. May be harmful if inhaled.
Chronic:
Not available.

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Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Get medical aid. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.

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Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
Use foam, dry chemical, or carbon dioxide.

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Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container.

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Section 7 - HANDLING and STORAGE
Handling:
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Storage:
Store in a cool, dry place. Store in a tightly closed container.

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Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 3322-70-1: Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

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Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Solid
Color: Not available.
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 142 - 144 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C9H16O5
Molecular Weight: 204.22

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Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Not available.
Conditions to Avoid:
Incompatible materials, exposure to moist air or water.
Incompatibilities with Other Materials:
Oxidizing agents, bases, amines, alcohols.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported

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Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 3322-70-1 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
2,2,5,5-Tetrakis(hydroxymethyl)cyclopentanone - Not listed by ACGIH, IARC, or NTP.

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Section 12 - ECOLOGICAL INFORMATION

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Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

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Section 14 - TRANSPORT INFORMATION

IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.

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Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XI
Risk Phrases:
R 36/37/38 Irritating to eyes, respiratory system
and skin.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 37/39 Wear suitable gloves and eye/face
protection.
WGK (Water Danger/Protection)
CAS# 3322-70-1: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 3322-70-1 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 3322-70-1 is not listed on the TSCA inventory.
It is for research and development use only.

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SECTION 16 - ADDITIONAL INFORMATION
N/A

反应信息

• 作为反应物：
  描述：

  2,2,5,5-四(羟基甲基)环戊酮 在 吡啶 、 lithium bromide 、 锌 作用下， 生成 dispiro[2.1.2⁵.2³]nonan-4-one
  参考文献：
  名称：

  Leriverend,P.; Conia,J.-M., Bulletin de la Societe Chimique de France, 1966, p. 116 - 120

  摘要：

  DOI：
• 作为产物：
  描述：

  聚合甲醛 、 环戊酮 在 水 、 potassium carbonate 作用下， 生成 2,2,5,5-四(羟基甲基)环戊酮
  参考文献：
  名称：

  Gault; Skoda, Bulletin de la Societe Chimique de France, 1946, p. 316,323

  摘要：

  DOI：

文献信息

• ELECTROCHROMIC COMPOUND, ELECTROCHROMIC COMPOSITION, AND ELECTROCHROMIC ELEMENT
  申请人：Goto Daisuke

  公开号：US20180208834A1

  公开（公告）日：2018-07-26

  An electrochromic compound represented by the following formula (1) is provided: where each of R 1 to R 9 and Ar 1 to Ar 6 independently represents one of a hydrogen atom, a halogen atom, a monovalent organic group, a group in which two or more aryl and/or heteroaryl groups are bound to each other via a covalent bond, a group in which two or more aryl and/or heteroaryl groups are condensed with each other to form a ring, and a polymerizable functional group; and at least one of Ar 1 to Ar 6 represents an aryl group, a heteroaryl group, a group in which two or more aryl and/or heteroaryl groups are bound to each other via a covalent bond, or a group in which at least two aryl or heteroaryl groups are condensed with each other to form a ring.

  提供以下式（1）所表示的一个电致变色化合物：其中R1至R9和Ar1至Ar6中的每一个独立表示氢原子、卤原子、一价有机基团、通过共价键相互连接的两个或更多芳基和/或杂环芳基组成的基团、通过共价键相互连接的两个或更多芳基和/或杂环芳基组成的环、以及可聚合的功能基团；并且Ar1至Ar6中至少有一个表示芳基、杂环芳基、通过共价键相互连接的两个或更多芳基和/或杂环芳基组成的基团，或者至少有两个芳基或杂环芳基通过共价键相互连接形成环。
• [EN] ELECTROCHROMIC COMPOUND, ELECTROCHROMIC COMPOSITION, AND ELECTROCHROMIC DISPLAY ELEMENT<br/>[FR] COMPOSÉ ÉLECTROCHROMIQUE, COMPOSITION ÉLECTROCHROMIQUE ET ÉLÉMENT D'AFFICHAGE ÉLECTROCHROMIQUE
  申请人：RICOH CO LTD

  公开号：WO2016203773A1

  公开（公告）日：2016-12-22

  Provided is an electrochromic compound represented by the following general formula (I) or (II) where R1 to R13 are each independently a hydrogen atom, a halogen atom, a monovalent organic group, or a polymerizable functional group, and at least one of the R1 to the R13 is a polymerizable functional group.

  提供的是一个由下列一般式（I）或（II）表示的电致变色化合物，其中R1至R13分别是氢原子、卤素原子、一价有机基团或可聚合功能基团，且R1至R13中至少有一个是可聚合功能基团。
• 2,2,5,5-TETRAMETHYLOLCYCLOPENTANOL PENTANITRATE
  作者：D. C. Downing

  DOI：10.1139/v52-017

  日期：1952.2.1

  Tetramethylolcyclopentanone was hydrogenated (70% purified yield) and nitrated (74% purified yield) to give 2,2,5,5-tetramethylolcyclopentanol pentanitrate, m.p. 91°, a powerful explosive only slightly weaker than RDX. A number of its properties were determined.

  四甲基环戊酮经过氢化（纯化收率70％）和硝化（纯化收率74％）后，得到2,2,5,5-四甲基环戊醇戊硝酸盐，熔点为91℃，是一种威力强大的炸药，仅略弱于RDX。已确定了它的许多性质。
• Coating liquid and electrophotographic photoreceptor prepared using the coating liquid
  申请人：Kondo Maiko

  公开号：US20060134540A1

  公开（公告）日：2006-06-22

  A coating liquid including an N-alkoxymethylated nylon and a solvent, wherein the N-alkoxymethylated nylon includes one or more ions in an amount of from 200 to 500 ppm based on a weight of the N-alkoxymethylated nylon or one or more alkylamines in an amount of from 15 to 100 ppm based on a weight of the N-alkoxymethylated nylon. A photoreceptor including an electroconductive substrate; a charge blocking layer located overlying the substrate; a moiré preventing layer located overlying the charge blocking layer; and a photosensitive layer located overlying the moiré preventing layer, wherein the charge blocking layer is formed using the coating liquid.

  一种包括N-烷氧甲基化尼龙和溶剂的涂层液，其中N-烷氧甲基化尼龙包括一种或多种离子，其量为基于N-烷氧甲基化尼龙重量的200至500 ppm，或者包括一种或多种烷基胺，其量为基于N-烷氧甲基化尼龙重量的15至100 ppm。一种包括导电基底的光敏感器，其上覆盖有电荷阻挡层，覆盖在电荷阻挡层上的是防止莫尔纹层，覆盖在防止莫尔纹层上的是光敏感层，其中电荷阻挡层是使用所述涂层液形成的。
• Image bearing member, method of manufacturing the same, image formation method, image forming apparatus and process cartridge
  申请人：Nagai Kazukiyo

  公开号：US20080304867A1

  公开（公告）日：2008-12-11

  An image bearing member including an electroconductive substrate, a photosensitive layer located overlying the electroconductive substrate and a cross linking surface layer comprising a charge transport curing compound and located overlying the photosensitive layer, wherein the charge transport curing compound includes a material including a structure unit represented by the following Chemical formula A: Chemical formula A where R 1 to R 5 and R 1 ′ to R 5 ′ independently represent a hydrogen atom, an alkyl group having 1 to 4 carbon atoms or an alkoxy group having 1 to 4 carbon atoms, R 6 represents a hydrogen atom or a methyl group and X represents an alkylene group having a straight chain or a branched chain having 2 to 5 carbon atoms.

  一种图像承载成员，包括导电基底、位于导电基底上方的感光层和包括电荷传输固化化合物、位于感光层上方的交联表面层，其中电荷传输固化化合物包括一种材料，该材料包括以下化学式A所表示的结构单元： 化学式A 其中R1至R5和R1'至R5'独立地表示氢原子、具有1至4个碳原子的烷基或具有1至4个碳原子的烷氧基，R6表示氢原子或甲基基团，X表示具有2至5个碳原子的直链或支链烷基。