1,6,7,12-四氯苝二-间苯二甲酸酰胺 | 1585236-32-3

• 物质功能分类: 有机原料 - 氨基化合物 - 酰胺类化合物
• 分子结构分类: 有机化合物 - 苯类化合物 - 菲及其衍生物
• 中文名称: 1,6,7,12-四氯苝二-间苯二甲酸酰胺
• 英文名称: 1,6,7,12-tetrachloro-3,4:9,10-perylene-dianhydride
• 英文别名: 5-[11,14,22,26-Tetrachloro-18-(3,5-dicarboxyphenyl)-6,8,17,19-tetraoxo-7,18-diazaheptacyclo[14.6.2.22,5.03,12.04,9.013,23.020,24]hexacosa-1(22),2(26),3,5(25),9,11,13,15,20,23-decaen-7-yl]benzene-1,3-dicarboxylic acid；5-[11,14,22,26-tetrachloro-18-(3,5-dicarboxyphenyl)-6,8,17,19-tetraoxo-7,18-diazaheptacyclo[14.6.2.22,5.03,12.04,9.013,23.020,24]hexacosa-1(22),2(26),3,5(25),9,11,13,15,20,23-decaen-7-yl]benzene-1,3-dicarboxylic acid
• CAS: 1585236-32-3
• 化学式: C₄₀H₁₄Cl₄N₂O₁₂
• 分子量: 856.369
• InChiKey: PTVQTGBJVXPJRY-UHFFFAOYSA-N

物化性质

• 密度：
  1.908±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  7.4
• 重原子数：
  58
• 可旋转键数：
  6
• 环数：
  9.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  224
• 氢给体数：
  4
• 氢受体数：
  12

反应信息

• 作为产物：
  描述：

  3,4,9,10-苝四羧酸二酐 在 咪唑 、 碘 作用下， 以 氯磺酸 为溶剂， 反应 32.0h， 生成 1,6,7,12-四氯苝二-间苯二甲酸酰胺
  参考文献：
  名称：

  水介质中供体Per-受体Per聚集体的光收集和发射放大

  摘要：

  借助合理的设计，我们合成了一对水溶性的供体和受体型扭曲的per双酰亚胺单元，它们在降低介质的pH值时一起形成聚集体，提供了明亮的黄色荧光。可以通过控制供体与受体的比例来调节共组装系统的光收集效率，并且已经实现了98.1％的效率。

  DOI：

  10.1002/chem.201304431

文献信息

• Antioxidants Having Aromatic Structures Reacting with Superoxide
  申请人：Tour James

  公开号：US20160175292A1

  公开（公告）日：2016-06-23

  Disclosed is a method of treating diseases which are: reactive oxygen species mediated, ischemic or reperfusion-related, or T-cell mediated, including autoimmune diseases. The method is administering a therapeutically effective amount of a formulation wherein the active ingredient includes non-phenolic aromatic structures that are electron deficient and are capable of converting the superoxide radical to O 2 ; and/or of converting superoxide radical to oxygen and hydrogen peroxide, or pharmaceutically acceptable salts of said structures. Also disclosed is a method of diagnosing and treating such diseases and conditions.

  本方法揭示了一种治疗疾病的方法，这些疾病包括：由活性氧自由基介导的、缺血或再灌注相关的、或T细胞介导的，包括自身免疫疾病。该方法是向患者施用含有非酚类芳香结构的活性成分的制剂，这些结构是电子不足的并且能够将超氧自由基转化为O2；和/或将超氧自由基转化为氧气和过氧化氢，或者这些结构的药用盐。还揭示了一种诊断和治疗这类疾病和病况的方法。
• Construction of Function‐Oriented Core–Shell Nanostructures in Hydrogen‐Bonded Organic Frameworks for Near‐Infrared‐Responsive Bacterial Inhibition
  作者：Bai‐Tong Liu、Xiao‐Hong Pan、Ding‐Yang Zhang、Rui Wang、Jun‐Yu Chen、Han‐Ru Fang、Tian‐Fu Liu

  DOI：10.1002/anie.202110028

  日期：2021.12

  AbstractExploration of effective ways to integrate various functional species into hydrogen‐bonded organic frameworks (HOFs) is critically important for their applications but highly challenging. In this study, according to the “bottle‐around‐ship” strategy, core–shell heterostructure of upconversion nanoparticles (UCNPs) and HOFs was fabricated for the first time via a ligand‐grafting stepwise method. The UCNPs “core” can effectively upconvert near‐infrared (NIR) irradiation (980 nm) into visible light (540 nm and 653 nm), which further excites the perylenediimide‐based HOF “shell” through resonance energy transfer. In this way, the nanocomposite inherits the high porosity, excellent photothermal and photodynamic efficiency, NIR photoresponse from two parent materials, achieving intriguing NIR‐responsive bacterial inhibition toward Escherichia coli. This study may shed light on the design of functional HOF‐based composite materials, not only enriching the HOF library but also broadening the horizon of their potential applications.
• Light Harvesting and Amplification of Emission of Donor Perylene-Acceptor Perylene Aggregates in Aqueous Medium
  作者：Pradip K. Sukul、Ayan Datta、Sudip Malik

  DOI：10.1002/chem.201304431

  日期：2014.3.10

  aid of rational design, we have synthesized a pair of water‐soluble donor‐ and acceptor‐type twisted perylene bisimide units, which together form aggregates upon lowering the pH of the medium, providing bright yellow fluorescence. The light‐harvesting efficiency of the co‐assembled system can be tuned by controlling the ratio of donor to acceptor and 98.1 % efficiency has been achieved.

  借助合理的设计，我们合成了一对水溶性的供体和受体型扭曲的per双酰亚胺单元，它们在降低介质的pH值时一起形成聚集体，提供了明亮的黄色荧光。可以通过控制供体与受体的比例来调节共组装系统的光收集效率，并且已经实现了98.1％的效率。