1-溴-2-萘甲醛 | 3378-82-3

• 物质功能分类: 化学试剂 - 有机试剂 - 芳香醛(含缩醛,半缩醛)
• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 中文名称: 1-溴-2-萘甲醛
• 中文别名: 1-溴-2-萘醛
• 英文名称: 1-bromo-2-naphthaldehyde
• 英文别名: 1-bromonaphthalene-2-carbaldehyde；1-bromo-2-formylnaphthalene；1-bromo-2-naphthalenecarboxaldehyde
• CAS: 3378-82-3
• 化学式: C₁₁H₇BrO
• 分子量: 235.08
• InChiKey: CYGUXEZVBLMVRV-UHFFFAOYSA-N

物化性质

• 熔点：
  118°C
• 沸点：
  347℃
• 密度：
  1.552
• 闪点：
  120℃
• 溶解度：
  溶于甲醇
• 稳定性/保质期：

  在常温常压下，该物质保持稳定。

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  13
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

安全信息

• 危险品标志：
  Xi
• 安全说明：
  S26,S37/39
• 危险类别码：
  R36/37/38
• WGK Germany：
  3
• 海关编码：
  2913000090
• 危险品运输编号：
  NONH for all modes of transport
• 危险性防范说明：
  P261,P305+P351+P338
• 危险性描述：
  H315,H319,H335
• 储存条件：
  存储条件：2-8℃，避光、通风干燥处，密封保存。

SDS

1-Bromo-2-naphthaldehyde Revision number: 1
SAFETY DATA SHEET

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Section 1. BASE INFORMATION
Product name: 1-Bromo-2-naphthaldehyde

Revision number: 1

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Section 2. HAZARDS IDENTIFICATION
Classification of the GHS
PHYSICAL HAZARDS Not classified
HEALTH HAZARDS
Category 2
Skin corrosion/irritation
Serious eye damage/eye irritation Category 2A
Not classified
ENVIRONMENTAL HAZARDS
GHS label elements
Pictograms or hazard symbols
Signal word Warning
Hazard statement Causes skin irritation
Causes serious eye irritation
Precautionary statements
[Prevention] Wash hands thoroughly after handling.
Wear protective gloves/eye protection/face protection.
[Response] IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses,
if present and easy to do. Continue rinsing.
If eye irritation persists: Get medical advice/attention.
IF ON SKIN: Gently wash with plenty of soap and water.
If skin irritation occurs: Get medical advice/attention.
Take off contaminated clothing and wash before reuse.

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Section 3. COMPOSITION/INFORMATION ON INGREDIENTS
Substance/mixture: Substance
Component(s): 1-Bromo-2-naphthaldehyde
Percent: >96.0%(GC)
CAS Number: 3378-82-3
Chemical Formula: C11H7BrO

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Section 4. FIRST AID MEASURES
Inhalation: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
Get medical advice/attention if you feel unwell.
Skin contact: Remove/Take off immediately all contaminated clothing. Gently wash with plenty of
soap and water. If skin irritation or rash occurs: Get medical advice/attention.
1-Bromo-2-naphthaldehyde

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Section 4. FIRST AID MEASURES
Eye contact: Rinse cautiously with water for several minutes. Remove contact lenses, if present
and easy to do. Continue rinsing. If eye irritation persists: Get medical
advice/attention.
Ingestion: Get medical advice/attention if you feel unwell. Rinse mouth.
Protection of first-aiders: A rescuer should wear personal protective equipment, such as rubber gloves and air-
tight goggles.

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Section 5. FIRE-FIGHTING MEASURES
Dry chemical, foam, water spray, carbon dioxide.
Suitable extinguishing
media:
Specific hazards: Take care as it may decompose upon combustion or in high temperatures to
generate poisonous fume.
Specific methods: Fire-extinguishing work is done from the windward and the suitable fire-extinguishing
method according to the surrounding situation is used. Uninvolved persons should
evacuate to a safe place. In case of fire in the surroundings: Remove movable
containers if safe to do so.
Special protective When extinguishing fire, be sure to wear personal protective equipment.
equipment for firefighters:

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Section 6. ACCIDENTAL RELEASE MEASURES
Personal precautions, Use personal protective equipment. Keep people away from and upwind of spill/leak.
protective equipment and Entry to non-involved personnel should be controlled around the leakage area by
emergency procedures: roping off, etc.
Environmental precautions: Prevent product from entering drains.
Methods and materials for Sweep dust to collect it into an airtight container, taking care not to disperse it.
containment and cleaning Adhered or collected material should be promptly disposed of, in accordance with
up: appropriate laws and regulations.

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Section 7. HANDLING AND STORAGE
Handling
Technical measures: Handling is performed in a well ventilated place. Wear suitable protective equipment.
Prevent dispersion of dust. Wash hands and face thoroughly after handling.
Use a local exhaust if dust or aerosol will be generated.
Advice on safe handling: Avoid contact with skin, eyes and clothing.
Storage
Keep container tightly closed. Store in a cool and dark place.
Storage conditions:
Store under inert gas.
Store away from incompatible materials such as oxidizing agents.
Packaging material: Law is followed.

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Section 8. EXPOSURE CONTROLS / PERSONAL PROTECTION
Engineering controls: Install a closed system or local exhaust as possible so that workers should not be
exposed directly. Also install safety shower and eye bath.
Personal protective equipment
Respiratory protection: Dust respirator. Follow local and national regulations.
Hand protection: Protective gloves.
Eye protection: Safety glasses. A face-shield, if the situation requires.
Skin and body protection: Protective clothing. Protective boots, if the situation requires.

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Section 9. PHYSICAL AND CHEMICAL PROPERTIES
Solid
Physical state (20°C):
Form: crystal - powder
Color: Very pale yellow - Pale yellow
Odor: No data available
pH: No data available
Melting point/freezing point:118 °C
1-Bromo-2-naphthaldehyde

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Section 9. PHYSICAL AND CHEMICAL PROPERTIES
Boiling Point/Range: No data available
Flash Point: No data available
Explosive limits
No data available
Lower:
Upper: No data available
No data available
Density:
Solubility: Soluble in : Methanol

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Section 10. STABILITY AND REACTIVITY
Stability: Stable under proper conditions.
Reactivity: No special reactivity has been reported.
Conditions to avoid: Air-sensitive
Incompartible materials: oxidizing agents
Hazardous Decomposition Carbon monoxide, Carbon dioxide, Hydrogen bromide
Products:

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Section 11. TOXICOLOGICAL INFORMATION
Acute Toxicity: No data available
Skin corrosion/irritation: No data available
Serious eye No data available
damage/irritation:
Germ cell mutagenicity: No data available
Carcinogenicity:
IARC = No data available
No data available
NTP =
Reproductive toxicity: No data available

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Section 12. ECOLOGICAL INFORMATION
Ecotoxicity:
Fish: No data available
Crustacea: No data available
Algae: No data available
Persistence / degradability: No data available
Bioaccumulative No data available
potential(BCF):
Mobillity in soil
log Pow: No data available
Soil adsorption (Koc): No data available
Henry's Law No data available
constant(PaM3/mol):

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Section 13. DISPOSAL CONSIDERATIONS
Recycle to process, if possible. Consult your local regional authorities. You may be able to dissolve or mix material
with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber system.
Observe all federal, state and local regulations when disposing of the substance.

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Section 14. TRANSPORT INFORMATION
Hazards Class: Does not correspond to the classification standard of the United Nations
UN-No: Not Listed

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Section 15. REGULATORY INFORMATION
Safe management ordinance of dangerous chemical product (State Council announces on January 26,
2002): Safe use and production, the storage of a dangerous chemical, transport, loading and unloading were
prescribed.
1-Bromo-2-naphthaldehyde

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SECTION 16 - ADDITIONAL INFORMATION
N/A

反应信息

• 作为反应物：
  描述：

  1-溴-2-萘甲醛 在 potassium permanganate 、 溴 、 铁粉 、 铜 作用下， 以 四氯化碳 、 乙醚 、 N,N-二甲基甲酰胺 、 丙酮 为溶剂， 反应 7.34h， 生成 dimethyl 1,1'-bis(4-bromo-2-naphthoate)
  参考文献：
  名称：

  三重 Diels-Alder 反应的对映选择性催化：范围和机制研究

  摘要：

  手性敏化剂 1,1'-双（2,4-二氰基萘）和 1,1'-双（2,10-二氰基蒽）的辐照催化反式-β-甲基苯乙烯与 1,3-环己二烯形成[4+2]环加合物endo-trans-6-methyl-5-phenylbicyclo[2.2.2]oct-2-ene。当敏化剂具有光学活性并在乙醚或甲苯溶液中低温照射时，对映选择性形成[4+2]环加合物

  DOI：

  10.1021/ja00050a011
• 作为产物：
  描述：

  2-甲基萘 在 盐酸 、 N-溴代丁二酰亚胺(NBS) 、 N₄(CH₂)6 、 溴 、 溶剂黄146 、 过氧化苯甲酰 作用下， 以 二硫化碳 、 四氯化碳 为溶剂， 反应 3.0h， 生成 1-溴-2-萘甲醛
  参考文献：
  名称：

  一种新颖的包合物设计：通过联萘铰链和附加的配位基团选择性地包含不带电的分子。1,1'-联萘-2,2'-二羧酸主体/羟基客体包裹体的X射线晶体结构和结合模式

  摘要：

  Etude de cinq clathrates du compose du titre (1) avec des alcools differents: 1.2 MeOH (P2 1 /n, Z=4), 1.2 EtOH (C2/c, Z=4), 1.2 (PrOH-2) (C2/ c, Z=4), 1.(RuOH-2) (P2 1 /n, Z=4), 1.乙二醇(P2 1 /n, Z=4)。关系

  DOI：

  10.1021/ja00323a039