sodium stearoyl lactylate | 25383-99-7

• 物质功能分类: 食品添加剂 - 乳化剂
• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: sodium stearoyl lactylate
• 英文别名: Sodium stearoyl-2-lactylate；sodium;2-(2-octadecanoyloxypropanoyloxy)propanoate
• CAS: 25383-99-7
• 化学式: C₂₄H₄₃O₆*Na
• 分子量: 450.592
• InChiKey: ODFAPIRLUPAQCQ-UHFFFAOYSA-M

物化性质

• 密度：
  1.002[at 20℃]
• LogP：
  4.13 at 20℃
• 物理描述：
  White or slightly yellowish powder or brittle solid with a characteristic odour
• 溶解度：
  Insoluble in water. Soluble in ethanol
• 酸价：
  Not less than 60 and not more than 130

计算性质

• 辛醇/水分配系数(LogP)：
  1.87
• 重原子数：
  31
• 可旋转键数：
  22
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  92.7
• 氢给体数：
  0
• 氢受体数：
  6

安全信息

• 危险性防范说明：
  P261,P305+P351+P338
• 危险性描述：
  H315,H319,H335
• 储存条件：
  2-8°C

SDS

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Section 1. Chemical Product and Company Identification
Sodium Stearoyl Lactylate
Common Name/
Trade Name
Sodium Stearoyl Lactylate

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Section 4. First Aid Measures
Eye Contact Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at
least 15 minutes. Cold water may be used. WARM water MUST be used. Get medical attention.
Skin Contact Wash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation develops.
Serious Skin Contact Not available.
Inhalation If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get
medical attention.
Serious Inhalation Not available.
Ingestion Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an
unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight
clothing such as a collar, tie, belt or waistband.
Serious Ingestion Not available.

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Section 5. Fire and Explosion Data
Flammability of the Product May be combustible at high temperature.
Auto-Ignition Temperature Not available.
Flash Points CLOSED CUP: 221.11°C (430°F).
Flammable Limits Not available.
Products of Combustion These products are carbon oxides (CO, CO2).
Fire Hazards in Presence of Slightly flammable to flammable in presence of heat.
Various Substances
Explosion Hazards in Presence Risks of explosion of the product in presence of mechanical impact: Not available.
Risks of explosion of the product in presence of static discharge: Not available.
of Various Substances
SMALL FIRE: Use DRY chemical powder.
Fire Fighting Media
and Instructions LARGE FIRE: Use water spray, fog or foam. Do not use water jet.
Not available.
Special Remarks on
Fire Hazards
Special Remarks on Explosion Not available.
Hazards

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Section 6. Accidental Release Measures
Small Spill Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by
spreading water on the contaminated surface and dispose of according to local and regional authority
requirements.
Large Spill Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water
on the contaminated surface and allow to evacuate through the sanitary system.
Sodium Stearoyl Lactylate

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Section 7. Handling and Storage
Precautions Keep away from heat. Keep away from sources of ignition. Empty containers pose a fire risk, evaporate the
residue under a fume hood. Ground all equipment containing material. Do not breathe dust. Avoid contact with
eyes. Wear suitable protective clothing. In case of insufficient ventilation, wear suitable respiratory equipment. If
you feel unwell, seek medical attention and show the label when possible. Keep away from incompatibles such as
moisture.
Storage HYGROSCOPIC. Keep container tightly closed. Keep container in a cool, well-ventilated area. Do not store
above 32°C (89.6°F).

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Section 8. Exposure Controls/Personal Protection
Engineering Controls Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below
recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to
airborne contaminants below the exposure limit.
Personal Protection Splash goggles. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent.
Gloves.
Personal Protection in Case of Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used
a Large Spill to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist
BEFORE handling this product.
Exposure Limits Not available.

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Section 9. Physical and Chemical Properties
Physical state and appearance Solid. (Solid powder.) Odor Sweetish. (Slight.)
Not available.
Taste
Molecular Weight 451.6 g/mole
Off-white.
Color
Not available.
pH (1% soln/water)
Boiling Point Not available.
48.889°C (120°F)
Melting Point
Critical Temperature Not available.
Specific Gravity 1.063 (Water = 1)
Vapor Pressure Not applicable.
Vapor Density Not available.
Not available.
Volatility
Odor Threshold Not available.
Water/Oil Dist. Coeff. Not available.
Ionicity (in Water) Not available.
Dispersion Properties Not available.
Solubility Very slightly soluble in cold water.

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Section 10. Stability and Reactivity Data
Stability The product is stable.
Instability Temperature Not available.
Conditions of Instability Not available.
Incompatibility with various Reactive with moisture.
substances
Sodium Stearoyl Lactylate
Corrosivity Not available.
Special Remarks on Hygroscopic
Reactivity
Special Remarks on Not available.
Corrosivity
Polymerization Will not occur.

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Section 11. Toxicological Information
Routes of Entry Inhalation. Ingestion.
Toxicity to Animals LD50: Not available.
LC50: Not available.
Chronic Effects on Humans Not available.
Other Toxic Effects on Hazardous in case of inhalation.
Humans
Slightly hazardous in case of skin contact (irritant), of ingestion.
Special Remarks on Not available.
Toxicity to Animals
Special Remarks on Not available.
Chronic Effects on Humans
Special Remarks on other Acute Potential Health effects:
Toxic Effects on Humans Eye: May cause slight irritation
Skin: May be an irritant. Contact with product at elevated temperatures can cause thermal burns.
Ingestion: Low level of toxicity. Believed to present very little hazard if swallowed. Acute toxicity via oral route of
administration is expected to be low. Sodium Stearoyl Lactylate is a food grade emulsifier, protein and starch
complexing agent and is not hazardous as defined in the Federal Substance Act. It also not toxic as defined in
OSHA Regulations 29CFR 1900.1200 - Appendix A - Health Hazard Definitions.
Inhalation: May be slightly irritating to respiratory tract.

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Section 12. Ecological Information
Ecotoxicity Not available.
Not available.
BOD5 and COD
Possibly hazardous short term degradation products are not likely. However, long term degradation products may
Products of Biodegradation
arise.
Toxicity of the Products The product itself and its products of degradation are not toxic.
of Biodegradation
Special Remarks on the Not available.
Products of Biodegradation

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Section 13. Disposal Considerations
Waste Disposal
Sodium Stearoyl Lactylate

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Section 14. Transport Information
DOT Classification Not a DOT controlled material (United States).
Identification Not applicable.
Not applicable.
Special Provisions for
Transport
DOT (Pictograms)

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Section 15. Other Regulatory Information and Pictograms
TSCA 8(b) inventory: Sodium Stearoyl Lactylate
Federal and State
Regulations
California
Proposition 65
Warnings
Other Regulations EINECS: This product is on the European Inventory of Existing Commercial Chemical Substances.
WHMIS (Canada) Not controlled under WHMIS (Canada).
Other Classifications
DSCL (EEC) R36- Irritating to eyes. S2- Keep out of the reach of children.
S46- If swallowed, seek medical advice
immediately and show this container or label.
Health Hazard
HMIS (U.S.A.) 2 National Fire Protection
1 Flammability
1 Association (U.S.A.)
Fire Hazard
2 2 Reactivity
Health
Reactivity
0
Specific hazard
Personal Protection
E
WHMIS (Canada)
(Pictograms)
DSCL (Europe)
(Pictograms)
TDG (Canada)
(Pictograms)
ADR (Europe)
(Pictograms)
Protective Equipment
Sodium Stearoyl Lactylate
Gloves.
Lab coat.
Dust respirator. Be sure to use an
approved/certified respirator or
equivalent.

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SECTION 16 - ADDITIONAL INFORMATION
N/A

制备方法与用途

化学性质

白色至淡黄色粉末，稍带特殊气味。溶于热动植物油及乙醇、丙酮、乙醚和氯仿等有机溶剂，难溶于水，但在水中激烈搅拌可完全分散。HLB值为8.3。大白鼠经口LD50为27.76g/kg（FAO/WHO，1994）。

用途

O-十八烷酰乳酸钠作为W/O型食品乳化剂，能与小麦粉中的面筋结合，增加面筋的稳定性和弹性，使面团蓬松柔软且不易老化。我国规定其最大使用量为2.0g/kg，可用于糕点和面包。

生产方法

一步法 将乳酸和硬脂酸以摩尔比2:1的比例投入反应釜中，加入硬脂酸质量1.5%的浓硫酸，在105℃下反应4小时至无水分蒸发。反应结束后降温，并缓缓加入氢氧化钠溶液中和，可配制成固体含量为10%的乳剂产品。

二步法 在轻度减压下聚合乳酸，然后在通入二氧化碳条件下，加入硬脂酸进行酯化，再加碳酸钠中和得粉状产品。但该方法控制乳酸聚合难度较大，可能导致产品质量不稳定。

三步法 分别制备硬脂酰氯和乳酰乳酸，然后再将两物酰化、中和而成。

鉴别试验

• 溶解性：不溶于水；溶于乙醇（OT-42）。
• 钠试验：取试样2g加入10ml稀盐酸试液(TS-117)，在水浴中加热5分钟，过滤后用氨试液(TS-13)中和滤液。加醋酸双氧铀锌试液(TS-253)。

毒性

ADI值为0～20mg/kg（FAO/WHO，2001）。GRAS（FDA，§172.846，2000）。

使用限量

• GB 2760-96：糕点、面包，最大使用量为2.0g/kg。
• FDA，§172.846(2000)：
  • 焙烤制品：0.5%（以小麦粉计）；
  • 馅料、布丁等表面活性剂、乳化剂、稳定剂：0.2%（最终成品）；
  • 油水乳化：无具体限量；
  • 脱水马铃薯：0.5%；
  • 小吃食品：0.2%。
• EEC(1990)：
  • 饼干、面包、蛋糕等焙烤制品：0.5%（以小麦粉计）；
  • 作为馅料、布丁等表面活性剂、乳化剂、稳定剂：0.2%（最终成品）；
  • 油水乳化：无具体限量；
  • 脱水马铃薯：0.5%；
  • 小吃食品：0.2%。

反应信息

• 作为产物：
  描述：

  乳酸 、 硬脂酸 在 sodium hydroxide 作用下， 以 水 为溶剂， 200.0 ℃ 、10.0 kPa 条件下， 反应 2.5h， 生成 sodium stearoyl lactylate
  参考文献：
  名称：

  一种脂肪酰乳酸或其盐的制备方法

  摘要：

  本发明公开了一种脂肪酰乳酸或其盐的制备方法。包括以下步骤：使用高浓度的乳酸水溶液投料，在低温、高真空条件下脱水，再与脂肪酸在固体催化剂作用下反应生成脂肪酰乳酸。所得脂肪酰乳酸根据需要中和成盐，即得脂肪酰乳酸盐。该工艺制备过程不使用有机溶剂，脂肪酸转化率较高，不需要经过提纯工序即可用于下游应用。

  公开号：

  CN111072471B

文献信息

• [EN] COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING SWEET TASTE<br/>[FR] COMPOSÉS, COMPOSITIONS ET PROCÉDÉS PERMETTANT DE MODULER LE GOÛT DE SUCRÉ
  申请人：CHROMOCELL CORP

  公开号：WO2014153000A1

  公开（公告）日：2014-09-25

  The present invention provides edible compositions comprising a sweet taste modulator of the present invention, food products comprising such edible compositions and methods of preparing such food products. The present invention also provides methods of reducing the amount of sugar in a food product, methods of reducing the caloric intake in a diet, and methods of enhancing sweet taste in a food product.

  本发明提供了包含本发明的甜味调节剂的食用组合物，包括这种食用组合物的食品产品以及制备这种食品产品的方法。本发明还提供了减少食品产品中糖的量的方法，减少饮食中热量摄入的方法，以及增强食品产品中甜味的方法。
• COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING SWEET TASTE
  申请人：Chromocell Corporation

  公开号：US20210282443A1

  公开（公告）日：2021-09-16

  The present disclosure provides edible compositions comprising a flavor-grade sweet taste modulator or a combination of flavor-grade sweet taste modulators or a flavor-grade bitter taste blocker or a combination of flavor-grade bitter taste blockers of the present disclosure, food products comprising such edible compositions and methods of preparing such food products. The present disclosure also provides methods of reducing the amount of sugar in a food product, methods of reducing the caloric intake in a diet, and methods of enhancing sweet taste or blocking a bitter taste in a food product.

  本公开说明提供了包含味级甜味调节剂或味级苦味阻断剂或二者组合的食品组成物，以及包含这种可食用组成物的食品产品和制备这种食品产品的方法。本公开说明还提供了减少食品产品中糖含量的方法、减少饮食热量摄入的方法，以及增强食品产品的甜味或阻断苦味的方法。
• Tamper resistant oral dosage forms containing an embolizing agent
  申请人：Soscia Anthony Edward

  公开号：US20100099696A1

  公开（公告）日：2010-04-22

  Oral dosage form containing a therapeutically effective amount of a drug susceptible to abuse and an effective amount of an embolizing agent which causes the production of a solid or semi-solid embolus or blockage after tampering.

  口服剂型包含治疗有效量易被滥用的药物和有效量的栓塞剂，该栓塞剂在篡改后会产生固体或半固体栓塞物或阻塞物。
• Haarspray-Zusammensetzung
  申请人：GOLDWELL AKTIENGESELLSCHAFT

  公开号：EP0535429A2

  公开（公告）日：1993-04-07

  Elastizität, Halt und Glanz des Haares werden durch Aufbringung einer Haarspray-Zusammensetzung, die zur Abgabe aus einer mechanischen Sprühvorrichtung oder mit verflüssigten Kohlenwasserstoff-Treibmitteln bzw. komprimierten Gasen vorgesehen ist, und neben etwa 30 bis 90 Gew.-% eines niedrigen Alkohols und etwa 1 bis 15 Gew.-% mindestens eines filmbildenen Polymeren auf wässriger Basis noch zusätzlich etwa 0,1 bis etwa 5 Gew-% mindestens eines C₆-C₁₈-Acyllactylats enthält, wesentlich verbessert.

  通过使用一种用于从机械喷雾装置或液化烃推进剂或压缩气体中喷出的头发喷雾组合物，除了约 30 至 90 wt.重量百分比的低醇和约 1 至 15 重量百分比的至少一种水基成膜聚合物，以及约 0.1 至约 5 重量百分比的至少一种 C₆-C₁₈-乙酰乳酸酯。
• Amin enthaltende Aerosolzusammensetzung und diese enthaltendes Haarspray
  申请人：GOLDWELL GmbH

  公开号：EP0832639A2

  公开（公告）日：1998-04-01

  Die vorliegende Erfindung betrifft Aerosolzusammensetzungen, insbesondere Haarsprays, auf Basis mindestens eines Lösungs- und mindestens eines Treibmittels sowie gegebenenfalls Wasser, die als korrosionsinhibierenden Bestandteil mindestens 0,001, vorzugsweise zwischen 0,01 und 0,1 Gew.-%, berechnet auf die Gesamtzusammensetzung, mindestens eines Amins aus der Gruppe 2-Amino-2-methyl-1-propanol, 2-Amino-2-methyl-1,3-propandiol und/oder Triiosopropanolamin enthalten.

  本发明涉及以至少一种溶剂和至少一种推进剂以及可选的水为基础的气溶胶组合物，特别是头发喷雾剂，其中含有按总组合物重量计算的至少 0.001%，最好是 0.01%至 0.1%的 2-氨基-2-甲基-1-丙醇、2-氨基-2-甲基-1,3-丙二醇和/或三代丙醇胺中的至少一种胺作为缓蚀成分。