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    —— (6R)-4-prop-2-enyl-1-(pyridin-3-ylmethyl)-6-[(4-pyridin-4-ylphenyl)methyl]-1,4-diazepan-5-one —— C26H28N4O
    (6R)-4-prop-2-enyl-1-(pyridin-3-ylmethyl)-6-[(4-pyridin-4-ylphenyl)methyl]-1,4-diazepan-5-one
    —— 6-(cyclohexylmethyl)-2-[(2S)-1-pyrrolidin-1-ylsulfonylpyrrolidin-2-yl]-3,5,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-one —— C22H35N5O3S
    6-(cyclohexylmethyl)-2-[(2S)-1-pyrrolidin-1-ylsulfonylpyrrolidin-2-yl]-3,5,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-one
    —— (6S)-1-(cyclobutanecarbonyl)-4-prop-2-enyl-6-[(4-pyridin-4-ylphenyl)methyl]-1,4-diazepan-5-one —— C25H29N3O2
    (6S)-1-(cyclobutanecarbonyl)-4-prop-2-enyl-6-[(4-pyridin-4-ylphenyl)methyl]-1,4-diazepan-5-one
    —— (6R)-4-prop-2-enyl-1-(pyridine-4-carbonyl)-6-[(4-thiophen-2-ylphenyl)methyl]-1,4-diazepan-5-one —— C25H25N3O2S
    (6R)-4-prop-2-enyl-1-(pyridine-4-carbonyl)-6-[(4-thiophen-2-ylphenyl)methyl]-1,4-diazepan-5-one
    —— (6S)-1-(3-fluorobenzoyl)-4-prop-2-enyl-6-[(4-pyridin-4-ylphenyl)methyl]-1,4-diazepan-5-one —— C27H26FN3O2
    (6S)-1-(3-fluorobenzoyl)-4-prop-2-enyl-6-[(4-pyridin-4-ylphenyl)methyl]-1,4-diazepan-5-one
    —— (6S)-4-prop-2-enyl-1-(pyridin-3-ylmethyl)-6-[(4-pyridin-4-ylphenyl)methyl]-1,4-diazepan-5-one —— C26H28N4O
    (6S)-4-prop-2-enyl-1-(pyridin-3-ylmethyl)-6-[(4-pyridin-4-ylphenyl)methyl]-1,4-diazepan-5-one
    —— (6R)-1-[(2R)-oxolane-2-carbonyl]-6-[(4-phenylphenyl)methyl]-4-prop-2-enyl-1,4-diazepan-5-one —— C26H30N2O3
    (6R)-1-[(2R)-oxolane-2-carbonyl]-6-[(4-phenylphenyl)methyl]-4-prop-2-enyl-1,4-diazepan-5-one
    —— (6S)-6-[(4-phenylphenyl)methyl]-4-prop-2-enyl-1-(1H-pyrazole-5-carbonyl)-1,4-diazepan-5-one —— C25H26N4O2
    (6S)-6-[(4-phenylphenyl)methyl]-4-prop-2-enyl-1-(1H-pyrazole-5-carbonyl)-1,4-diazepan-5-one
    —— 6-(cyclohexylmethyl)-2-[(2R)-1-pyrrolidin-1-ylsulfonylpyrrolidin-2-yl]-3,5,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-one —— C22H35N5O3S
    6-(cyclohexylmethyl)-2-[(2R)-1-pyrrolidin-1-ylsulfonylpyrrolidin-2-yl]-3,5,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-one
    —— (6S)-1-[(2R)-oxolane-2-carbonyl]-4-prop-2-enyl-6-[(4-pyridin-4-ylphenyl)methyl]-1,4-diazepan-5-one —— C25H29N3O3
    (6S)-1-[(2R)-oxolane-2-carbonyl]-4-prop-2-enyl-6-[(4-pyridin-4-ylphenyl)methyl]-1,4-diazepan-5-one
    —— (6R)-4-prop-2-enyl-1-(2-pyridin-3-ylacetyl)-6-[(4-thiophen-2-ylphenyl)methyl]-1,4-diazepan-5-one —— C26H27N3O2S
    (6R)-4-prop-2-enyl-1-(2-pyridin-3-ylacetyl)-6-[(4-thiophen-2-ylphenyl)methyl]-1,4-diazepan-5-one
    —— (6R)-6-[(3-phenylphenyl)methyl]-4-prop-2-enyl-1-[3-(tetrazol-1-yl)propanoyl]-1,4-diazepan-5-one —— C25H28N6O2
    (6R)-6-[(3-phenylphenyl)methyl]-4-prop-2-enyl-1-[3-(tetrazol-1-yl)propanoyl]-1,4-diazepan-5-one
    —— (6S)-6-[[4-(2-fluorophenyl)phenyl]methyl]-4-prop-2-enyl-1-[2-(1,2,4-triazol-1-yl)acetyl]-1,4-diazepan-5-one —— C25H26FN5O2
    (6S)-6-[[4-(2-fluorophenyl)phenyl]methyl]-4-prop-2-enyl-1-[2-(1,2,4-triazol-1-yl)acetyl]-1,4-diazepan-5-one
    —— (6S)-6-[[4-(2-fluorophenyl)phenyl]methyl]-1-[(2S)-5-oxopyrrolidine-2-carbonyl]-4-prop-2-enyl-1,4-diazepan-5-one —— C26H28FN3O3
    (6S)-6-[[4-(2-fluorophenyl)phenyl]methyl]-1-[(2S)-5-oxopyrrolidine-2-carbonyl]-4-prop-2-enyl-1,4-diazepan-5-one
    —— 6-(2-cyclohexylacetyl)-2-[(2S)-1-[(2S)-oxolane-2-carbonyl]pyrrolidin-2-yl]-3,5,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-one —— C24H34N4O4
    6-(2-cyclohexylacetyl)-2-[(2S)-1-[(2S)-oxolane-2-carbonyl]pyrrolidin-2-yl]-3,5,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-one
    —— (6R)-4-prop-2-enyl-1-(pyridin-3-ylmethyl)-6-[(4-pyridin-3-ylphenyl)methyl]-1,4-diazepan-5-one —— C26H28N4O
    (6R)-4-prop-2-enyl-1-(pyridin-3-ylmethyl)-6-[(4-pyridin-3-ylphenyl)methyl]-1,4-diazepan-5-one
    —— (6R)-6-[(4-phenylphenyl)methyl]-4-prop-2-enyl-1-(2-pyridin-3-ylacetyl)-1,4-diazepan-5-one —— C28H29N3O2
    (6R)-6-[(4-phenylphenyl)methyl]-4-prop-2-enyl-1-(2-pyridin-3-ylacetyl)-1,4-diazepan-5-one
    —— (6R)-1-(1,2-oxazole-5-carbonyl)-6-[(4-phenylphenyl)methyl]-4-prop-2-enyl-1,4-diazepan-5-one —— C25H25N3O3
    (6R)-1-(1,2-oxazole-5-carbonyl)-6-[(4-phenylphenyl)methyl]-4-prop-2-enyl-1,4-diazepan-5-one
    —— (6S)-6-[(4-phenylphenyl)methyl]-4-prop-2-enyl-1-(3-pyrazol-1-ylpropanoyl)-1,4-diazepan-5-one —— C27H30N4O2
    (6S)-6-[(4-phenylphenyl)methyl]-4-prop-2-enyl-1-(3-pyrazol-1-ylpropanoyl)-1,4-diazepan-5-one
    —— (6R)-4-prop-2-enyl-1-(pyridine-2-carbonyl)-6-[(3-pyridin-3-ylphenyl)methyl]-1,4-diazepan-5-one —— C26H26N4O2
    (6R)-4-prop-2-enyl-1-(pyridine-2-carbonyl)-6-[(3-pyridin-3-ylphenyl)methyl]-1,4-diazepan-5-one
    —— (6R)-1-[(2S)-5-oxopyrrolidine-2-carbonyl]-4-prop-2-enyl-6-[(3-pyridin-3-ylphenyl)methyl]-1,4-diazepan-5-one —— C25H28N4O3
    (6R)-1-[(2S)-5-oxopyrrolidine-2-carbonyl]-4-prop-2-enyl-6-[(3-pyridin-3-ylphenyl)methyl]-1,4-diazepan-5-one
    —— (6S)-4-prop-2-enyl-1-(pyridin-2-ylmethyl)-6-[(4-pyridin-3-ylphenyl)methyl]-1,4-diazepan-5-one —— C26H28N4O
    (6S)-4-prop-2-enyl-1-(pyridin-2-ylmethyl)-6-[(4-pyridin-3-ylphenyl)methyl]-1,4-diazepan-5-one
    —— (6S)-1-(1H-imidazol-2-ylmethyl)-4-prop-2-enyl-6-[(4-thiophen-2-ylphenyl)methyl]-1,4-diazepan-5-one —— C23H26N4OS
    (6S)-1-(1H-imidazol-2-ylmethyl)-4-prop-2-enyl-6-[(4-thiophen-2-ylphenyl)methyl]-1,4-diazepan-5-one
    —— (6R)-4-prop-2-enyl-1-(pyridine-4-carbonyl)-6-[(4-pyridin-3-ylphenyl)methyl]-1,4-diazepan-5-one —— C26H26N4O2
    (6R)-4-prop-2-enyl-1-(pyridine-4-carbonyl)-6-[(4-pyridin-3-ylphenyl)methyl]-1,4-diazepan-5-one
    —— (6R)-1-(cyclobutanecarbonyl)-4-prop-2-enyl-6-[(4-pyridin-4-ylphenyl)methyl]-1,4-diazepan-5-one —— C25H29N3O2
    (6R)-1-(cyclobutanecarbonyl)-4-prop-2-enyl-6-[(4-pyridin-4-ylphenyl)methyl]-1,4-diazepan-5-one
    —— (6R)-1-(6-oxo-4,5-dihydro-1H-pyridazine-3-carbonyl)-4-prop-2-enyl-6-[(2-pyridin-3-ylphenyl)methyl]-1,4-diazepan-5-one —— C25H27N5O3
    (6R)-1-(6-oxo-4,5-dihydro-1H-pyridazine-3-carbonyl)-4-prop-2-enyl-6-[(2-pyridin-3-ylphenyl)methyl]-1,4-diazepan-5-one
    —— (6S)-4-prop-2-enyl-1-(pyridin-2-ylmethyl)-6-[(4-pyridin-4-ylphenyl)methyl]-1,4-diazepan-5-one —— C26H28N4O
    (6S)-4-prop-2-enyl-1-(pyridin-2-ylmethyl)-6-[(4-pyridin-4-ylphenyl)methyl]-1,4-diazepan-5-one
    —— (6S)-6-[[4-(2-fluorophenyl)phenyl]methyl]-4-prop-2-enyl-1-(pyridine-2-carbonyl)-1,4-diazepan-5-one —— C27H26FN3O2
    (6S)-6-[[4-(2-fluorophenyl)phenyl]methyl]-4-prop-2-enyl-1-(pyridine-2-carbonyl)-1,4-diazepan-5-one
    —— (6R)-1-[(2S)-oxolane-2-carbonyl]-6-[(4-phenylphenyl)methyl]-4-prop-2-enyl-1,4-diazepan-5-one —— C26H30N2O3
    (6R)-1-[(2S)-oxolane-2-carbonyl]-6-[(4-phenylphenyl)methyl]-4-prop-2-enyl-1,4-diazepan-5-one
    —— 6-(cyclopropanecarbonyl)-2-[(2S)-1-(cyclopropanecarbonyl)piperidin-2-yl]-3,5,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-one —— C20H26N4O3
    6-(cyclopropanecarbonyl)-2-[(2S)-1-(cyclopropanecarbonyl)piperidin-2-yl]-3,5,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-one
    —— 6-(cyclopropanecarbonyl)-2-[(2R)-1-[(2S)-oxolane-2-carbonyl]piperidin-2-yl]-3,5,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-one —— C21H28N4O4
    6-(cyclopropanecarbonyl)-2-[(2R)-1-[(2S)-oxolane-2-carbonyl]piperidin-2-yl]-3,5,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-one
    —— (6S)-1-[(2R)-5-oxopyrrolidine-2-carbonyl]-6-[(3-phenylphenyl)methyl]-4-prop-2-enyl-1,4-diazepan-5-one —— C26H29N3O3
    (6S)-1-[(2R)-5-oxopyrrolidine-2-carbonyl]-6-[(3-phenylphenyl)methyl]-4-prop-2-enyl-1,4-diazepan-5-one
    —— (6R)-1-[3-[(2S)-oxolan-2-yl]propanoyl]-6-[(3-phenylphenyl)methyl]-4-prop-2-enyl-1,4-diazepan-5-one —— C28H34N2O3
    (6R)-1-[3-[(2S)-oxolan-2-yl]propanoyl]-6-[(3-phenylphenyl)methyl]-4-prop-2-enyl-1,4-diazepan-5-one
    —— 6-(cyclopropanecarbonyl)-2-[(2S)-1-[(2R)-oxolane-2-carbonyl]piperidin-2-yl]-3,5,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-one —— C21H28N4O4
    6-(cyclopropanecarbonyl)-2-[(2S)-1-[(2R)-oxolane-2-carbonyl]piperidin-2-yl]-3,5,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-one
    —— (6R)-4-prop-2-enyl-1-(pyridin-4-ylmethyl)-6-[(4-pyridin-3-ylphenyl)methyl]-1,4-diazepan-5-one —— C26H28N4O
    (6R)-4-prop-2-enyl-1-(pyridin-4-ylmethyl)-6-[(4-pyridin-3-ylphenyl)methyl]-1,4-diazepan-5-one
    —— (6R)-1-[2-(2-oxopyrrolidin-1-yl)acetyl]-6-[(3-phenylphenyl)methyl]-4-prop-2-enyl-1,4-diazepan-5-one —— C27H31N3O3
    (6R)-1-[2-(2-oxopyrrolidin-1-yl)acetyl]-6-[(3-phenylphenyl)methyl]-4-prop-2-enyl-1,4-diazepan-5-one
    —— (6R)-4-prop-2-enyl-1-(2-pyridin-3-ylacetyl)-6-[(4-pyridin-4-ylphenyl)methyl]-1,4-diazepan-5-one —— C27H28N4O2
    (6R)-4-prop-2-enyl-1-(2-pyridin-3-ylacetyl)-6-[(4-pyridin-4-ylphenyl)methyl]-1,4-diazepan-5-one
    —— (6R)-6-[(4-phenylphenyl)methyl]-4-prop-2-enyl-1-(2-pyridin-2-ylacetyl)-1,4-diazepan-5-one —— C28H29N3O2
    (6R)-6-[(4-phenylphenyl)methyl]-4-prop-2-enyl-1-(2-pyridin-2-ylacetyl)-1,4-diazepan-5-one
    —— (6S)-6-[(4-phenylphenyl)methyl]-4-prop-2-enyl-1-(2-pyridin-3-ylacetyl)-1,4-diazepan-5-one —— C28H29N3O2
    (6S)-6-[(4-phenylphenyl)methyl]-4-prop-2-enyl-1-(2-pyridin-3-ylacetyl)-1,4-diazepan-5-one
    —— (6R)-6-[[4-(2-fluorophenyl)phenyl]methyl]-4-prop-2-enyl-1-(1H-1,2,4-triazole-5-carbonyl)-1,4-diazepan-5-one —— C24H24FN5O2
    (6R)-6-[[4-(2-fluorophenyl)phenyl]methyl]-4-prop-2-enyl-1-(1H-1,2,4-triazole-5-carbonyl)-1,4-diazepan-5-one
    —— (6S)-6-[[4-(2-fluorophenyl)phenyl]methyl]-1-[(2R)-5-oxopyrrolidine-2-carbonyl]-4-prop-2-enyl-1,4-diazepan-5-one —— C26H28FN3O3
    (6S)-6-[[4-(2-fluorophenyl)phenyl]methyl]-1-[(2R)-5-oxopyrrolidine-2-carbonyl]-4-prop-2-enyl-1,4-diazepan-5-one
    —— (6R)-6-[[4-(2-fluorophenyl)phenyl]methyl]-4-prop-2-enyl-1-(pyridine-2-carbonyl)-1,4-diazepan-5-one —— C27H26FN3O2
    (6R)-6-[[4-(2-fluorophenyl)phenyl]methyl]-4-prop-2-enyl-1-(pyridine-2-carbonyl)-1,4-diazepan-5-one
    —— (6S)-1-[(2S)-oxolane-2-carbonyl]-6-[(4-phenylphenyl)methyl]-4-prop-2-enyl-1,4-diazepan-5-one —— C26H30N2O3
    (6S)-1-[(2S)-oxolane-2-carbonyl]-6-[(4-phenylphenyl)methyl]-4-prop-2-enyl-1,4-diazepan-5-one
    —— (6S)-1-[(2S)-oxolane-2-carbonyl]-4-prop-2-enyl-6-[(4-pyridin-4-ylphenyl)methyl]-1,4-diazepan-5-one —— C25H29N3O3
    (6S)-1-[(2S)-oxolane-2-carbonyl]-4-prop-2-enyl-6-[(4-pyridin-4-ylphenyl)methyl]-1,4-diazepan-5-one
    —— (6R)-6-[(4-phenylphenyl)methyl]-4-prop-2-enyl-1-(pyridine-4-carbonyl)-1,4-diazepan-5-one —— C27H27N3O2
    (6R)-6-[(4-phenylphenyl)methyl]-4-prop-2-enyl-1-(pyridine-4-carbonyl)-1,4-diazepan-5-one
    —— 6-(cyclohexylmethyl)-2-[(2S)-1-[(3R)-oxolane-3-carbonyl]pyrrolidin-2-yl]-3,5,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-one —— C23H34N4O3
    6-(cyclohexylmethyl)-2-[(2S)-1-[(3R)-oxolane-3-carbonyl]pyrrolidin-2-yl]-3,5,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-one
    —— 6-(2-cyclopentylacetyl)-2-[(2R)-1-(cyclopropanecarbonyl)piperidin-2-yl]-3,5,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-one —— C23H32N4O3
    6-(2-cyclopentylacetyl)-2-[(2R)-1-(cyclopropanecarbonyl)piperidin-2-yl]-3,5,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-one
    —— 6-[(2R)-oxolane-2-carbonyl]-2-pyrrolidin-1-yl-3,5,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-one —— C16H22N4O3
    6-[(2R)-oxolane-2-carbonyl]-2-pyrrolidin-1-yl-3,5,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-one
    —— 6-(2-cyclopentylacetyl)-2-[(2S)-1-(cyclopropanecarbonyl)piperidin-2-yl]-3,5,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-one —— C23H32N4O3
    6-(2-cyclopentylacetyl)-2-[(2S)-1-(cyclopropanecarbonyl)piperidin-2-yl]-3,5,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-one
    —— 6-(2-cyclopentylacetyl)-2-[(2S)-1-[(2S)-oxolane-2-carbonyl]piperidin-2-yl]-3,5,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-one —— C24H34N4O4
    6-(2-cyclopentylacetyl)-2-[(2S)-1-[(2S)-oxolane-2-carbonyl]piperidin-2-yl]-3,5,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-one