Enantiospecific synthesis and confirmation of the relative and absolute stereostructure of 11-hydroxyguaiadienes
摘要:
Enantiospecific total synthesis of two epimeric sesquiterpenes 11-hydroxyguaiadienes has been accomplished starting from the readily available monoterpene (R)-limonene, which confirmed the structure and absolute configuration of the natural products. (C) 2010 Elsevier Ltd. All rights reserved.
8-endo Cyclization of (alkoxycarbonyl)methyl radicals: Stereoselective synthesis of (−)-clavukerin A and (−)-11-hydroxyguaiene
作者:Eun Lee、Cheol Hwan Yoon
DOI:10.1016/0040-4039(96)01279-8
日期:1996.8
(−)-Clavukerin A was synthesized from (+)-limonene oxide via 8-endoradicalcyclization. (−)-11-Hydroxyguaiene was also synthesized, but its spectroscopic data did not match with those reported for the natural product.