[(1S,2R,4S,10R,11R,16R)-6-(Furan-3-yl)-1,7,11,15,15-pentamethyl-5,14-dioxo-3-oxapentacyclo[8.8.0.02,4.02,7.011,16]octadec-12-en-18-yl] acetate | 18385-59-6

• 物质功能分类: 有机原料 - 酮类化合物
• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: [(1S,2R,4S,10R,11R,16R)-6-(Furan-3-yl)-1,7,11,15,15-pentamethyl-5,14-dioxo-3-oxapentacyclo[8.8.0.02,4.02,7.011,16]octadec-12-en-18-yl] acetate
• CAS: 18385-59-6
• 化学式: C₂₈H₃₄O₆
• 分子量: 466.6
• InChiKey: NEYCGDYQBQONFC-AMVLTCCSSA-N

物化性质

• 熔点：
  >180°C (dec.)
• 沸点：
  569.1±50.0 °C(Predicted)
• 密度：
  1.25±0.1 g/cm3(Predicted)
• 溶解度：
  可溶于氯仿（少许）、甲醇（少许）

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  34
• 可旋转键数：
  3
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.68
• 拓扑面积：
  86.1
• 氢给体数：
  0
• 氢受体数：
  6

文献信息

• Antiviral Compositions And Methods Of Using The Same
  申请人：Kim Joseph Jong

  公开号：US20070259844A1

  公开（公告）日：2007-11-08

  Pharmaceutical compositions for and methods of preventing infection or treating an individual who has been identified as being infected with a Flavivirus, Pestivirus, picornovirus or coronavirus such as HCV, GB virus B, JEV, WNV, CSFV, BDV, BVDV, poliovirus, FMDV, or EMCV, comprising administering to the individual a therapeutically effective amount of one or more glucocorticoid receptor antagonist compounds, wherein said compound has steroidal structure are disclosed.
• Compositions for and Methods for Treating Hiv
  申请人：Kim Joseph Jong

  公开号：US20070259014A1

  公开（公告）日：2007-11-08

  Pharmaceutical composition comprising compounds and/or compositions useful to inhibit HIV replication are disclosed. Methods of treating individuals infected with HIV are disclosed. Methods of preventing HIV infection in high risk individuals are disclosed.
• METHODS FOR TREATING VIRAL INFECTION WITH ORAL OR INJECTIBEL DRUG SOLUTION
  申请人：Kim Jong Joseph

  公开号：US20090074721A1

  公开（公告）日：2009-03-19

  Pharmaceutical composition comprising compounds and/or compositions useful to inhibit viral replication are disclosed.