The present invention relates to useful diterpenes and pharmaceutical compositions containing them of the formula:
for use in the treatment of cardiovascular and inflammatory diseases and for cancers susceptible to an NF-κB inhibitor and an endothelin receptor inhibitor. The present invention also relates to compounds and methods useful to inhibit cell proliferation and for the induction of apoptosis.
本发明涉及有用的二萜化合物及包含它们的药物组合物,用于治疗心血管和炎症性疾病,以及对NF-κB
抑制剂和内皮素受体
抑制剂敏感的癌症。本发明还涉及用于抑制细胞增殖和诱导凋亡的化合物和方法。