3'-甲氧基香豆雌酚 | 13360-66-2

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 异黄酮类化合物
• 中文名称: 3'-甲氧基香豆雌酚
• 英文名称: 3'-methoxycoumestrol
• 英文别名: 3,9-dihydroxy-8-methoxy-[1]benzofuro[3,2-c]chromen-6-one
• CAS: 13360-66-2
• 化学式: C₁₆H₁₀O₆
• 分子量: 298.252
• InChiKey: MQORJFLPGOCLDS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  22
• 可旋转键数：
  1
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  89.1
• 氢给体数：
  2
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  3-苄氧基苯甲醛 在 palladium on activated charcoal 、 palladium dichloride 盐酸 、 氢氧化钾 、 氢气 、 间氯过氧苯甲酸 、 2,3-二氯-5,6-二氰基-1,4-苯醌 、 lithium chloride 作用下， 以 四氢呋喃 、 二氯甲烷 、 水 、 丙酮 为溶剂， 25.0 ℃ 、303.98 kPa 条件下， 反应 84.0h， 生成 3'-甲氧基香豆雌酚
  参考文献：
  名称：

  Structure–activity relationship of wedelolactone analogues: Structural requirements for inhibition of Na+,K+-ATPase and binding to the central benzodiazepine receptor

  摘要：

  Coumestans 2a-i, bearing different patterns of substitution in A- and D-rings, were synthesized and evaluated as inhibitors of kidney Na+, K+ -ATPase and ligands for the central benzodiazepine (BZP) receptor. The presence of a hydroxyl group in position 2 favours the effect on Na+, K+ -ATPase but decreases the affinity for the BZP receptor, allowing the design of more selective molecules than the natural wedelolactone. On the other hand, the presence of a catechol in ring D is important for the effect on both molecular targets.

  DOI：

  10.1016/j.bmc.2006.07.053

文献信息

• Hydroponic plant nutrient kit and method of use
  申请人：Straumietis James Michael

  公开号：US20060168881A1

  公开（公告）日：2006-08-03

  The present invention provides a complete, safe, cost-effective, simple-to-use, and pH balanced hydroponics nutrient feeding kit for culturing plants indoors, outdoors and in green houses, wherein the hydroponics nutrient feeding kit comprises a set of formulations for making chronologically sequential nutrient solutions to culture a hydroponic crop through an entire growth cycle, wherein each formulation comprises all of the nutrient components required in a batch of nutrient solution. The nutrient components are pre-measured for a specific hydroponic nutrient reservoir size to consistently provide plants with their nutrient requirements for the specific stage of growth through the vegetative phase and the flowering and fruiting phase through to harvest. The hydroponics nutrient feeding system can be used with rock-wool, sphagnum moss, leca, coir, lava rock, soil mixes, aeroponics, drip irrigation, flood and drain, wick, NFT, systems and all other hydroponic growth mediums and systems.

  本发明提供了一种用于室内、室外和温室培养植物的完整、安全、经济高效、使用简便和 pH 值平衡的水培营养饲喂套件，其中水培营养饲喂套件包括一套用于按时间顺序配制营养液的配方，以培养水培作物的整个生长周期，其中每个配方包括一批营养液中所需的所有营养成分。营养成分是根据特定的水培营养库大小预先测量的，以持续提供植物在无性生长阶段、开花结果阶段直至收获的特定生长阶段所需的营养。水培营养液供给系统可与岩棉、石炭藓、莱卡、椰壳纤维、熔岩、混合土壤、气培、滴灌、漫灌和排水、灯芯、NFT 系统以及所有其他水培生长介质和系统一起使用。
• Structure–activity relationship of wedelolactone analogues: Structural requirements for inhibition of Na+,K+-ATPase and binding to the central benzodiazepine receptor
  作者：Elisa S.C. Pôças、Daniele V.S. Lopes、Alcides J.M. da Silva、Paulo H.C. Pimenta、Fernanda B. Leitão、Chaquip D. Netto、Camilla D. Buarque、Flávia V. Brito、Paulo R.R. Costa、François Noël

  DOI：10.1016/j.bmc.2006.07.053

  日期：2006.12

  Coumestans 2a-i, bearing different patterns of substitution in A- and D-rings, were synthesized and evaluated as inhibitors of kidney Na+, K+ -ATPase and ligands for the central benzodiazepine (BZP) receptor. The presence of a hydroxyl group in position 2 favours the effect on Na+, K+ -ATPase but decreases the affinity for the BZP receptor, allowing the design of more selective molecules than the natural wedelolactone. On the other hand, the presence of a catechol in ring D is important for the effect on both molecular targets.