Zederone | 7727-79-9

• 物质功能分类: 天然产物 - 倍半萜
• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: Zederone
• 英文别名: (8E)-5,9,14-trimethyl-4,12-dioxatricyclo[9.3.0.03,5]tetradeca-1(11),8,13-trien-2-one
• CAS: 7727-79-9
• 化学式: C₁₅H₁₈O₃
• 分子量: 246.3
• InChiKey: CVIVANCKIBYAOP-WEVVVXLNSA-N

物化性质

• 熔点：
  153.4-153.9℃ (acetone hexane )
• 溶解度：
  溶于氯仿、二氯甲烷、乙酸乙酯、DMSO、丙酮等。
• 物理描述：
  Solid

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  18
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  42.7
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• SYNERGISTIC HERBAL COMPOSITIONS FOR PREVENTION, TREATMENT OR CONTROL OF PAIN AND/OR CARTILAGE REGENERATION
  申请人：LAILA NUTRACEUTICALS

  公开号：US20220143124A1

  公开（公告）日：2022-05-12

  Disclosed herein is Synergistic herbal composition(s) comprising combination of a first ingredient selected from the extract(s), fraction(s), phytochemical(s) and mixtures thereof derived from Murraya koenigii and a second ingredient selected from the extract(s), fraction(s), phytochemical(s) and mixtures thereof derived from Coriandrum sativum or Curcuma amada for improving cartilage growth/repair/regeneration, improving joint mobility, reducing cartilage breakdown, reducing joint pain, reducing stiffness, reducing inflammation and/or treating/alleviating symptoms associated with osteoarthritis. The invention further provides method of improving cartilage growth/repair/regeneration, improving joint mobility, reducing cartilage breakdown, reducing joint pain, reducing stiffness, reducing inflammation and/or treating/alleviating symptoms associated with osteoarthritis in a human or animal.