含芦竹素 | 4555-56-0

• 物质功能分类: 生物化工 - 中草药成分
• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 中文名称: 含芦竹素
• 中文别名: 含芦竹素；芦竹素；含芦竹素;芦竹素;含芦竹萜
• 英文名称: arundoin
• 英文别名: fernenol methyl ether；Arundoin; Fernenol-methylether；(3R,3aR,5aR,5bR,7aR,9S,11aS,13aS,13bR)-9-methoxy-3a,5a,8,8,11a,13a-hexamethyl-3-propan-2-yl-1,2,3,4,5,5b,6,7,7a,9,10,11,13,13b-tetradecahydrocyclopenta[a]chrysene
• CAS: 4555-56-0
• 化学式: C₃₁H₅₂O
• 分子量: 440.753
• InChiKey: MRNPHCMRIQYRFU-KXUMSINMSA-N

物化性质

• 熔点：
  242-243 °C
• 沸点：
  484.9±34.0 °C(Predicted)
• 密度：
  0.98±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  9.5
• 重原子数：
  32
• 可旋转键数：
  2
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.94
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  含芦竹素 在 对甲苯磺酸 作用下， 以 乙酸酐 、 溶剂黄146 为溶剂， 生成 10-Desmethyl-5β-methyl-abeo-5(4-3)-3αH-Δ^1(10),8(11)-fernadien
  参考文献：
  名称：

  Arundoin，cylindrin和fernenol的结构：圆叶白茅（Imperata cylindrica var）的蕨类和芳族烷烃基团的三萜类化合物。科尼希

  摘要：

  已分离出五种三萜类化合物，即芦丁素（Ia），圆柱蛋白（IIa），蕨烯醇（Ib），异芳醇（IIb）和辛二烯醇（IVa），并确定了Ia，IIa和Ib的结构。

  DOI：

  10.1016/0040-4020(68)88023-8

文献信息

• AN COMPOSITION CONTAINING TRITERPENOID SAPONINS EXTRACTED FROM BAMBOO, AND THE PREPARATION METHOD AND USE THEREOF
  申请人：Zhejiang University (Hangzhou) Leaf Bio-Technology Co., Ltd.

  公开号：EP1576958A1

  公开（公告）日：2005-09-21

  The invention relates to a composition containing total triterpenoid sapogenins extracted from bamboo, the preparation method and use thereof. These total triterpenoid sapogenins are extracted from many parts of bamboo such as bamboo shavings in Gramineae by CO2 Supercritical Fluid Extraction technique. In the extract, the content of total triterpenoid sapogenins is 10-90%, while the contents of friedelin and lupenone are 5-35% and 1-10%, respectively. The extract in the invention has good physiological and pharmacological activities such as anti-free radical, anti-oxidation, anti-tumor and anti-hypertension. It can be used in medicines or functional foods for the treatment or prevention of cardiovascular and cerebrovascular diseases and tumor. It is also useful in cosmetics field.

  本发明涉及一种含有从竹子中提取的总三萜类苷元的组合物及其制备方法和用途。这些总三萜苷元是通过二氧化碳超临界流体萃取技术从竹子的许多部分（如禾本科竹屑）中提取出来的。在提取物中，总三萜苷元的含量为 10-90%，而油菜素和羽扇豆酮的含量分别为 5-35%和 1-10%。本发明中的提取物具有良好的生理和药理活性，如抗自由基、抗氧化、抗肿瘤、抗高血压等。它可用于治疗或预防心脑血管疾病和肿瘤的药物或功能性食品中。它还可用于化妆品领域。
• Antistress composition for a stress prevention and treatment
  申请人：Byung Hag Choi

  公开号：US20020054920A1

  公开（公告）日：2002-05-09

  The present invention provides antistress compositions contaning various medicinal herbs which are composed of one or more of medicinal herb 2.0˜40.0 g of fructus hordel germintus, messa medicata fermentata, frucutus amomi and fructus crataegei; hone or more of medicinal herb 2.0˜40.0 g of radix polygalae, semen zizyphi spinosae and rhizoma acori graminei; one or more of medicinal herb 2.0˜40.0 g selected from the group of poria holen and poria, one or more of medicinal herb 2.0˜40.0 g of folium phyllostachyos, calus in taein phyllostachos, succus phyllostachos and radix scutellariae; one or more of medicinal herb 2.0˜40.0 g of legumonosae, fructus amomicardamomi, semen glycine and semen lablab; one or more of medicinal herb 2.0˜40.0 g of rhizoma zingiberis, radix asari, rhizoma zingiberis siccatum and radix aconiti; one or more of medicinal herb 2.0˜40.0 g of bulbos allii fistulosi, herba ephedrae and folium perillae; and one or more of medicinal herb 2.0˜40.0 g of red pepper and radix platycodi as the effective ingredients that relieve stress and represse of a memory failure that releive stress and repress of a memory failure.

  本发明提供了含有多种药材的抗抑郁组合物，这些药材由以下一种或多种药材组成 2.0 ˜40.0 克 枸杞子、枸杞子酵母、枸杞子杏仁 和 枸杞子； 一种或多种药材 2.0 ˜40.0 克，包括 远志、酸枣仁 和 一种或多种 选自以下组别的一种或多种药材 2.0˜40.0 克 茯苓 和茯苓中的一种或多种药材 2.0˜40.0 克 一种或多种药材 2.0˜40.0 克，选自茯苓和茯苓组；一种或多种药材 2.0˜40.0 克，选自茯苓叶、茯苓茎、茯苓肉 和 黄芩； 一种或多种药材 2.0 ˜40.0 克豆科植物、 枸杞子、甘氨酸精液 和 一种或多种 一种或多种药材 2.0˜40.0 克 一种或多种药材 2.0˜40.0克 和 乌头； 一种或多种药材 2.0˜40.0g，包括 一种或多种药材 2.0˜40.0 克 和 folium perillae； 红辣椒和桔梗中的一种或多种药材 2.0˜40.0g；以及 桔梗 作为有效成分，可缓解压力和记忆力衰退，释放压力和抑制记忆力衰退。
• Chinese traditional medicines for psoriasis
  申请人：——

  公开号：US20030152588A1

  公开（公告）日：2003-08-14

  The invention relates to disclose some Chinese formula for psoriasis. Whether treatment for psoriasis is targeted at both the hyperproliferative and inflammatory aspect of the topical therapy. Specially, the administration dosage is soft gel, cream, tincture and aerosol etc. topical dosages.
• Composition containing total triterpenoid saponins extracted from bamboo, and the preparation method and use thereof
  申请人：Zhang Ying

  公开号：US20060148733A1

  公开（公告）日：2006-07-06

  The invention relates to a composition containing total triterpenoid sapogenins extracted from bamboo, the preparation method and use thereof. These total triterpenoid sapogenins are extracted from many parts of bamboo such as bamboo shavings in Gramineae by CO 2 Supercritical Fluid Extraction technique. In the extract, the content of total triterpenoid sapogenins is 10-90%, while the contents of friedelin and lupenone are 5-35% and 1-10%, respectively. The extract in the invention has good physiological and pharmacological activities such as anti-free radical, anti-oxidation, anti-tumor and anti-hypertension. It can be used in medicines or functional foods for the treatment or prevention of cardiovascular and cerebrovascular diseases and tumor. It is also useful in cosmetics field.
• US5466452A
  申请人：——

  公开号：US5466452A

  公开（公告）日：1995-11-14

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