聚十八烯酸一甘油酯 | 91782-95-5

• 物质功能分类: 食品添加剂 - 乳化剂
• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 聚十八烯酸一甘油酯
• 中文别名: 聚甘油-1 油酸酯；(Z)-9-十八烯酸与1,2,3-丙三醇的酯化物；甘油油酸酯；聚甘油单油酸酯；聚甘油-10油酸酯；甘油油酸酯;；(Z)-9-十八碳烯酸1,2,3-丙烷三醇酯
• 英文名称: Glycerine oleate
• 英文别名: (Z)-octadec-9-enoic acid;propane-1,2,3-triol
• CAS: 91782-95-5；37220-82-9；9007-48-1
• 化学式: C21H42O5
• 分子量: 374.6
• InChiKey: FABAOYOFJNAVHB-KVVVOXFISA-N

物化性质

• 熔点：
  <0 °C
• LogP：
  -4.147 (est)

计算性质

• 辛醇/水分配系数(LogP)：
  4.44
• 重原子数：
  26
• 可旋转键数：
  17
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  98
• 氢给体数：
  4
• 氢受体数：
  5

制备方法与用途

化学性质
这是一种浅黄色的黏稠液体，无特殊气味，味道微甜。它可溶于苯、甘油、丙二醇、热乙醇和冷的乙酸乙酯，但不溶于冷水；在热水中搅拌后可以分散成乳浊液。其HLB值为8～14.5（四聚至十聚物）。实验结果显示，大白鼠的LD₅₀为20g/kg，根据FAO/WHO（1994）的规定，ADI值为0～25mg/kg。

用途
它是一种良好的W/O型食品乳化剂，具备优良的分散和乳化作用。我国规定其可用于乳酸菌饮料、植物蛋白饮料、雪糕、冰棍和冰淇淋中，最大使用量为10.0g/kg。

生产方法
有关聚甘油单硬脂酸酯的生产方法，请参见相关资料。

文献信息

• ELECTRODE FOR IONTOPHORESIS AND DEVICE USING THE SAME
  申请人：HISAMITSU PHARMACEUTICAL CO. INC.

  公开号：EP0774272A1

  公开（公告）日：1997-05-21

  This invention relates to an iontophoresis electrode which is applicable to mucous membranes and oral mucous membranes, and especially capable of sticking directly on human oral mucous membranes and excellent in efficiently administering medicine and extremely easy to handle and lightweight. An iontophoresis electrode (Ka) of this invention comprises a backing layer (1) and, a conductive layer for current dispersion (2) made of silver or silver chloride that laminated on the backing layer (1) and, a spacer layer (3) of film, sheet, or cloth shape which is made of dried polymer layer with water soluble and swelling properties and laminated on the conductive layer for current dispersion, and can be sticked to the oral mucous membrane.

  本发明涉及一种离子透入电极，它适用于粘膜和口腔粘膜，特别是能够直接贴在人的口腔粘膜上，在高效给药方面表现出色，而且极易操作，重量轻。 本发明的电离子渗透电极（Ka）由背衬层（1）、层压在背衬层（1）上的由银或氯化银制成的电流分散导电层（2）和层压在电流分散导电层上的由具有水溶性和溶胀性的干燥聚合物层制成的薄膜、片状或布状的间隔层（3）组成，可粘贴在口腔粘膜上。
• PLASTER STRUCTURE FOR IONTOPHORESIS
  申请人：HISAMITSU PHARMACEUTICAL CO. INC.

  公开号：EP0846473A1

  公开（公告）日：1998-06-10

  It is an object of this invention to provide a plaster structure for iontophoresis in which a predetermined amount of physiologically active agents initially set can be stably kept or held without any loss until it is applied to a patient, and when the agents are applied to the patient, the predetermined amount of physiologically active agents initially set can be applied stably and continuously to an entire body of the patient and concurrently a mutual action between the physiologically active agents or additive agents and the adhesive agent is prevented, an adhering power of the adhesive agent is kept and it may not be peeled off during its application. The plaster structure for iontophoresis is comprised of an electrical conductive medicinal substance storing layer 1 containing the physiologically active agents, a backing layer 2 covering the medicinal substance storing layer 1 and having an electrode 3 installed therein, a protection layer 4 supporting the medicinal substance storing layer 1 and which is non-permeable against the physiologically active agents, an adhesive agent layer 5 comprised of pressure-sensitive adhesive agent with a superior skin adhering characteristic and/or mucous membrane adhering characteristic laminated on the other surface of the protection layer 4, a liner layer 6 laminated on the other surface of the adhesive agent layer 5, and a notch part 7 formed in the protection layer 4.

  本发明的目的是提供一种用于离子透入疗法的膏药结构，在这种结构中，最初设定的预定量的生理活性剂可以稳定地保存或保持，直到涂抹到患者身上，并且当这些生理活性剂涂抹到患者身上时不会有任何损失、可将最初设定的预定量生理活性剂稳定、连续地涂抹到患者全身，同时可防止生理活性剂或添加剂与粘合剂之间的相互影响，保持粘合剂的粘附力，并且在涂抹过程中不会剥落。 用于离子透入疗法的膏药结构由以下部分组成：含有生理活性剂的导电药剂储存层 1；覆盖药剂储存层 1 并在其中安装电极 3 的背衬层 2；支撑药剂储存层 1 且不渗透生理活性剂的保护层 4、粘合剂层 5，由具有良好的皮肤粘合特性和/或粘膜粘合特性的压敏粘合剂组成，层压在保护层 4 的另一个表面上；衬垫层 6，层压在粘合剂层 5 的另一个表面上；以及在保护层 4 上形成的凹槽部分 7。
• DEODORANTS
  申请人：Kao Corporation

  公开号：EP1197204A1

  公开（公告）日：2002-04-17

  The present invention provides a liquid deodorant suitable for deodorization of spaces and fiber products, and a hair cosmetic and skin cosmetic having a high deodorization effect. Here, any of the hair cosmetic and skin cosmetic may be that referred to as a body deodorant. Namely, the present invention provides a deodorant comprising a deodorant organic dibasic acid composed of an organic dibasic acid and/or salt thereof having a difference between the first acid dissociation index (hereinafter, abbreviated as first acid dissociation index) and the second acid dissociation index (hereinafter, abbreviated as second acid dissociation index or pK2) of 1.7 or more at 25°C.

  本发明提供了一种适用于空间和纤维制品除臭的液体除臭剂，以及一种具有高除臭效果的头发化妆品和皮肤化妆品。在此，头发化妆品和皮肤化妆品中的任何一种都可以被称为身体除臭剂。也就是说，本发明提供了一种除臭剂，该除臭剂包含由有机二元酸和/或其盐组成的除臭有机二元酸，在 25°C 时，其第一酸解离指数（以下简称第一酸解离指数）与第二酸解离指数（以下简称第二酸解离指数或 pK2）之差为 1.7 或以上。
• COSMETICS AND PROCESS FOR PRODUCTION THEREOF
  申请人：Hakuto Co., Ltd

  公开号：EP1820538A1

  公开（公告）日：2007-08-22

  An emulsion and dispersion system exhibiting excellent stability against heat and excellent stability over a long period time in interfaces between functional oily bases and water, or between functional granules as solid particles and water, etc., a cosmetic composition containing an emulsifying dispersant which is capable of performing emulsification and dispersion independently of required HLB values of the functional oily bases or the surface states of the functional granules, and a producing method of such a cosmetic composition. A cosmetic composition characterized in that an emulsifying dispersant including polysaccharides with particulate structure as a main component, and components to be emulsified are contained, and a producing method thereof. And a cosmetic composition characterized in that the emulsifying dispersant exists as a three-phase emulsifying dispersant which adheres to a periphery of the components to be emulsified like a layer to form an intermediate layer, and a producing method thereof.

  一种乳液和分散体系，在功能性油基与水或作为固体颗粒的功能性颗粒与水等之间的界面上具有优异的耐热稳定性和长时间稳定性；一种含有乳化分散剂的化妆品组合物，该乳化分散剂能够独立于功能性油基所需的 HLB 值或功能性颗粒的表面状态进行乳化和分散；以及这种化妆品组合物的生产方法。一种化妆品组合物，其特征在于含有一种乳化分散剂，该分散剂的主要成分是具有微粒结构的多糖，以及需要乳化的成分，及其生产方法。一种化妆品组合物，其特征在于该乳化分散剂以三相乳化分散剂的形式存在，像一层一样附着在待乳化成分的外围，形成中间层，以及其生产方法。
• Disinfectant formulation
  申请人：LABORATOIRE M2

  公开号：US10111425B2

  公开（公告）日：2018-10-30

  An aqueous disinfectant formulation comprising at least one phenolic compound of natural origin; a surfactant sufficient to form a solution or dispersion of the essential oil in an aqueous carrier; a solvent, and sufficient water to make 100 weight percent is described herein.

  本文介绍了一种水性消毒剂配方，它包含至少一种天然来源的酚类化合物；一种足以在水性载体中形成精油溶液或分散液的表面活性剂；一种溶剂和足够的水，重量百分比为 100%。