methyl 2,3-di-O-benzoyl-4,6-O-((R)-1-methoxycarbonylethylidene)-β-D-galactopyranosyl-(1-->4)-3,6-di-O-benzyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl-(1-->3) 2,4-di-O-benzyl-β-L-fucopyranoside | 208644-74-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: methyl 2,3-di-O-benzoyl-4,6-O-((R)-1-methoxycarbonylethylidene)-β-D-galactopyranosyl-(1-->4)-3,6-di-O-benzyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl-(1-->3) 2,4-di-O-benzyl-β-L-fucopyranoside
• 英文别名: methyl 2,3-di-O-benzoyl-4,6-O-((R)-1-methoxycarbonylethylidene)-β-D-galactopyranosyl-(1->4)-3,6-di-O-benzyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl-(1->3) 2,4-di-O-benzyl-β-L-fucopyranoside
• CAS: 208644-74-0
• 化学式: C₇₃H₇₃NO₂₀
• 分子量: 1284.38
• InChiKey: SWCSOQUVYQWCQN-FXPJRRAASA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.99
• 重原子数：
  94.0
• 可旋转键数：
  24.0
• 环数：
  12.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  227.04
• 氢给体数：
  0.0
• 氢受体数：
  20.0

反应信息

• 作为反应物：
  描述：

  methyl 2,3-di-O-benzoyl-4,6-O-((R)-1-methoxycarbonylethylidene)-β-D-galactopyranosyl-(1-->4)-3,6-di-O-benzyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl-(1-->3) 2,4-di-O-benzyl-β-L-fucopyranoside 在 palladium on activated charcoal 吡啶 、 sodium hydroxide 、 sodium tetrahydroborate 、 氢气 、 sodium methylate 、 乙酸酐 、 溶剂黄146 作用下， 生成
  参考文献：
  名称：

  Chemical Synthesis of (4,6-Pyr)-Gal β1→4GlcNAcβ1→3Fucβ1→OMe: A Pyruvated Trisaccharide Related to the Cell Aggregation of the SpongeMicrociona Prolifera

  摘要：

  4,6-O-[(R)-1-carboxylethylidene] Gal beta 1-->4GlcNAc beta 1-->3Fuc beta 1-->OMe, a pyruvated trisaccharide unit involved in the aggregation factor of the marine sponge Microciona prolifera, was synthesized stereospecifically and unambiguously employing thioglycosides as glycosyl donors to construct glycosidic bonds.

  DOI：

  10.1080/07328309808002904
• 作为产物：
  描述：

  phenyl 3,6-di-O-benzyl-2-deoxy-2-phthalimido-1-thio-β-D-glucopyranoside 在 吡啶 、 N-碘代丁二酰亚胺 、 4 A molecular sieve 、 sodium methylate 、 silver trifluoromethanesulfonate 作用下， 以 甲醇 、 二氯甲烷 、 甲苯 为溶剂， 反应 1.75h， 生成 methyl 2,3-di-O-benzoyl-4,6-O-((R)-1-methoxycarbonylethylidene)-β-D-galactopyranosyl-(1-->4)-3,6-di-O-benzyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl-(1-->3) 2,4-di-O-benzyl-β-L-fucopyranoside
  参考文献：
  名称：

  Chemical Synthesis of (4,6-Pyr)-Gal β1→4GlcNAcβ1→3Fucβ1→OMe: A Pyruvated Trisaccharide Related to the Cell Aggregation of the SpongeMicrociona Prolifera

  摘要：

  4,6-O-[(R)-1-carboxylethylidene] Gal beta 1-->4GlcNAc beta 1-->3Fuc beta 1-->OMe, a pyruvated trisaccharide unit involved in the aggregation factor of the marine sponge Microciona prolifera, was synthesized stereospecifically and unambiguously employing thioglycosides as glycosyl donors to construct glycosidic bonds.

  DOI：

  10.1080/07328309808002904