10-十九烷醇 | 16840-84-9

• 物质功能分类: 有机原料 - 醇、酚、酚醇类化合物及衍生物 - 无环醇
• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 10-十九烷醇
• 中文别名: 10-十九醇
• 英文名称: 10-nonadecanol
• 英文别名: nonadecan-10-ol；Nonadecanol-(10)
• CAS: 16840-84-9
• 化学式: C₁₉H₄₀O
• mdl: MFCD00046740
• 分子量: 284.526
• InChiKey: ACMBVSPXQQUNOF-UHFFFAOYSA-N

物化性质

• 沸点：
  357°C (estimate)
• 密度：
  0.8528 (estimate)
• LogP：
  8.325 (est)

计算性质

• 辛醇/水分配系数(LogP)：
  8.6
• 重原子数：
  20
• 可旋转键数：
  16
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

安全信息

• 海关编码：
  2905199090
• 安全说明：
  S22,S24/25
• 危险性防范说明：
  P264,P280,P302+P352,P337+P313,P305+P351+P338,P362+P364,P332+P313
• 危险性描述：
  H315,H319

反应信息

• 作为反应物：
  描述：

  10-十九烷醇 在 palladium on activated charcoal sodium azide 、 氢气 、 三乙胺 作用下， 以 四氢呋喃 、 正己烷 、 二氯甲烷 、 N,N-二甲基甲酰胺 为溶剂， 20.0~85.0 ℃ 、427.48 kPa 条件下， 反应 7.25h， 生成 di-tert-butyl 4-(2-tert-butoxycarbonylethyl)-4-[3-(1-nonyldecyl)ureido]heptanedioate
  参考文献：
  名称：

  Synthesis and antimicrobial activity of symmetrical two-tailed dendritic tricarboxylato amphiphiles

  摘要：

  Two series of water-soluble, symmetrical two-tailed homologous dendritic amphiphiles-R2NCONHC((CH2)(2)COOH)(3), 2(n,n), and R2CHNHCONHC((CH2))(2)COOH)(3), 3(n,n), where R = n-CnH2n+1-were synthesized and compared to R"NHCONHC((CH2)(2)CoOH)(3), 1(n), R" = n-CnH2n+1, to determine whether antimicrobial activity was influenced by total or individual alkyl chain lengths, and whether antimicrobial activity depends on hydrophobicity or tail topology (one or two). In a broad screen of 11 microorganisms, 2(n,n) and 3(n,n) generally displayed higher minimal inhibitory concentrations (MICs) than I(n) against growth as measured by broth microdilution assays. Chain-length specificity was observed against Candida albicans as 1(16), 2(8,8), and 3(8,8) showed the lowest MIC in their respective series. The one case where two-tailed compounds displayed the lowest MICs-3(10,10), 15 mu M; 3(11,11), 7.2 mu M; and 3(12,12), 6.9 mu M-was against Cryptococcus neoformans. (c) 2007 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmc.2007.03.017
• 作为产物：
  描述：

  10-十九烷酮 在 sodium tetrahydroborate 作用下， 以 四氢呋喃 、 甲醇 为溶剂， 反应 2.0h， 以95%的产率得到10-十九烷醇
  参考文献：
  名称：

  [EN] COMPOUNDS USEFUL IN HIV THERAPY
  [FR] COMPOSÉS UTILES DANS LA THÉRAPIE DU VIH

  摘要：

  这项发明涉及公式（I）的化合物，其盐，药物组合物，以及治疗或预防HIV的方法。

  公开号：

  WO2021194828A1

文献信息

• Liquid-Crystalline Phases Made of Gold Nanoparticles
  作者：Michal Wojcik、Wiktor Lewandowski、Joanna Matraszek、Jozef Mieczkowski、Jolanta Borysiuk、Damian Pociecha、Ewa Gorecka

  DOI：10.1002/anie.200901206

  日期：2009.6.29

  Spontaneous formation of smectic and columnar structures was observed when spherical gold nanoparticles were functionalized with mesogenic thiols (see layered structure and X‐ray pattern of a sample in smectic phase). The particle ordering is stimulated by softening of the interparticle potential and flexibility for deformation of the grafting layer.

  当球形金纳米颗粒被介晶硫醇官能化时，观察到自发形成近晶和柱状结构（请参见层状结构和近晶相样品​​的X射线图）。通过软化粒子间的电势和使接枝层变形的柔韧性，可以促进粒子的有序性。
• Production of Distillate Fuels from Biomass-Derived Polyoxygenates
  申请人：VIRENT, INC.

  公开号：US20130263498A1

  公开（公告）日：2013-10-10

  The present invention provides methods, reactor systems and catalysts for converting biomass and biomass-derived feedstocks to C 8+ hydrocarbons using heterogenous catalysts. The product stream may be separated and further processed for use in chemical applications, or as a neat fuel or a blending component in jet fuel and diesel fuel, or as heavy oils for lubricant and/or fuel oil applications.

  本发明提供了将生物质和生物质衍生原料转化为C8+烃的方法、反应器系统和催化剂，使用的是异质催化剂。产品流可以分离并进一步加工，用于化学应用，或作为纯净燃料或混合组分用于喷气燃料和柴油燃料，或作为润滑剂和/或燃油应用的重质油。
• CATALYSTS FOR HYDRODEOXYGENATION OF OXYGENATED HYDROCARBONS
  申请人：Blank Brian

  公开号：US20140051872A1

  公开（公告）日：2014-02-20

  The present invention provides catalysts, methods, and reactor systems for converting oxygenated hydrocarbons to oxygenated compounds. The invention includes methods for producing cyclic ethers, monooxygenates, dioxygenates, ketones, aldehydes, carboxylic acids, and alcohols from oxygenated hydrocarbons, such as carbohydrates, sugars, sugar alcohols, sugar degradation products, and the like, using catalysts containing palladium, molybdenum, tin, and tungsten. The oxygenated compounds produced are useful in the production of liquid fuels, chemicals, and other products.

  本发明提供了将含氧碳氢化合物转化为含氧化合物的催化剂、方法和反应器系统。该发明包括利用含有钯、钼、锡和钨的催化剂从含氧碳氢化合物（如碳水化合物、糖类、糖醇、糖降解产物等）生产环氧醚、单氧化物、双氧化物、酮、醛、羧酸和醇的方法。生产的含氧化合物可用于生产液体燃料、化学品和其他产品。
• [EN] BIOFUELS VIA HYDROGENOLYSIS-CONDENSATION<br/>[FR] BIOCOMBUSTIBLES OBTENUS PAR HYDROGÉNOLYSE-CONDENSATION
  申请人：SHELL OIL CO

  公开号：WO2011082001A1

  公开（公告）日：2011-07-07

  A method comprises a providing a carbohydrate; reacting the carbohydrate directly with hydrogen in the presence of a hydrogenolysis catalyst to produce a reaction product comprising a polyol; and then processing at least a portion of the reaction product to form a fuel blend.

  一种方法包括提供一个碳水化合物；在氢解催化剂的存在下直接将碳水化合物与氢反应，以产生包含多元醇的反应产物；然后处理至少反应产物的一部分以形成燃料混合物。
• Tailored Oils Produced from Recombinant Oleaginous Microorganisms
  申请人：Franklin Scott

  公开号：US20120203018A1

  公开（公告）日：2012-08-09

  Methods and compositions for the production of oil, fuels, oleochemicals, and other compounds in recombinant microorganisms are provided, including oil-bearing microorganisms and methods of low cost cultivation of such microorganisms. Microalgal cells containing exogenous genes encoding, for example, a lipase, a sucrose transporter, a sucrose invertase, a fructokinase, a polysaccharide-degrading enzyme, a keto acyl-ACP synthase enzyme, a fatty acyl-ACP thioesterase, a fatty acyl-CoA/aldehyde reductase, a fatty acyl-CoA reductase, a fatty aldehyde reductase, a fatty acid hydroxylase, a desaturase enzyme, a fatty aldehyde decarbonylase, and/or an acyl carrier protein are useful in manufacturing transportation fuels such as renewable diesel, biodiesel, and renewable jet fuel, as well as oleochemicals such as functional fluids, surfactants, soaps and lubricants.

  本文提供了用于在重组微生物中生产油、燃料、油脂化学品和其他化合物的方法和组合物，包括含油微生物和低成本培养这种微生物的方法。含有外源基因编码脂肪酶、蔗糖转运蛋白、蔗糖转化酶、果糖激酶、多糖降解酶、酮基酰基-ACP合酶酶、脂肪酰-ACP硫酯酶、脂肪酰-CoA/醛还原酶、脂肪酰-CoA还原酶、脂肪醛还原酶、脂肪酸羟化酶、不饱和酶、脂肪醛脱羰基酶和/或酰基载体蛋白的微藻细胞可用于制造可再生柴油、生物柴油和可再生喷气燃料，以及油脂化学品，如功能流体、表面活性剂、肥皂和润滑剂。

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