An oxo-pyridine fusion ring derivative compound represented by chemical formula 1 or a pharmaceutically acceptable salt thereof according to the present invention effectively inhibits the activity of RON and can not only effectively suppress the cell growth of cancer cell lines in which RON is activated, but also can effectively kill the cancer cell lines. Therefore, the oxo-pyridine fusion ring derivative compound represented by chemical formula 1 or a pharmaceutically acceptable salt thereof according to the present invention can be advantageously used for preventing or treating a disease associated with protein kinase activity.
根据本发明,
化学式1所代表的一种氧代
吡啶融合环衍
生物化合物或其药学上可接受的盐,可以有效抑制RON的活性,不仅可以有效抑制RON被激活的癌
细胞系的细胞生长,还可以有效杀死癌
细胞系。因此,根据本发明,
化学式1所代表的氧代
吡啶融合环衍
生物化合物或其药学上可接受的盐可以有利地用于预防或治疗与蛋白激酶活性相关的疾病。