圣草酚-7-O-葡糖苷 | 38965-51-4

• 物质功能分类: 天然产物 - 黄酮类化合物
• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 中文名称: 圣草酚-7-O-葡糖苷
• 英文名称: pyracanthoside
• 英文别名: eriodictyol 7-O-glucoside；miscanthoside；eriodictyol 7-β-D-glucopyranoside；eriodictyol 7-O-β-D-glucopyranoside；(2S)-eriodictyol 7-O-β-D-glucopyranoside；eriodictyol 7-O-β-glucoside；eriodictyol 7-O-glucopyranoside；Eriodictyol-7-O-glucoside；(2S)-2-(3,4-dihydroxyphenyl)-5-hydroxy-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,3-dihydrochromen-4-one
• CAS: 38965-51-4
• 化学式: C₂₁H₂₂O₁₁
• 分子量: 450.399
• InChiKey: RAFHNDRXYHOLSH-SFTVRKLSSA-N

物化性质

• 熔点：
  171-176°C
• 沸点：
  841.0±65.0 °C(Predicted)
• 密度：
  1.665±0.06 g/cm3(Predicted)
• 溶解度：
  DMSO:4.5(最大浓度 mg/mL);10.0(最大浓度 mM)
• LogP：
  0.220 (est)

计算性质

• 辛醇/水分配系数(LogP)：
  0.2
• 重原子数：
  32
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  186
• 氢给体数：
  7
• 氢受体数：
  11

安全信息

• 安全说明：
  S22,S24/25
• WGK Germany：
  3

反应信息

• 作为反应物：
  描述：

  圣草酚-7-O-葡糖苷 在 盐酸 作用下， 以 甲醇 为溶剂， 反应 2.0h， 生成 葡萄糖
  参考文献：
  名称：

  Phenolic constituents of the aerial parts of Impatiens glandulifera Royle (Balsaminaceae) and their antioxidant activities

  摘要：

  As a continuation of investigating Impatiens L. genus, eight flavonoids, eriodyctiol, eriodyctiol 7-O-beta-& x1d05;-glucoside, kaempferol 3-O-beta-& x1d05;-glucoside, kaempferol 3-O-beta-& x1d05;-galactoside, kaempferol 3-rhamnosyl-di-glucoside, kaempferol 3-O-beta-& x1d05;-rutinoside, quercetin 3-O-beta-& x1d05;-glucoside and quercetin 3-O-beta-& x1d05;-galactoside, two phenolic acids - p-hydroxybenzoic acid and protocatechuic acid, and 2-methoxynaphthalene-1,4-dione were isolated from the aerial parts of I. glandulifera collected in Poland. The structures of the compounds were established by analysis of their spectroscopic (H-1 and C-13 NMR) and spectrometric (MS) data, as well as by comparison of these with those reported in the literature. Quercetin 3-O-beta-& x1d05;-glucoside, kaempferol 3-O-beta-& x1d05;-galactoside and kaempferol 3-O-beta-& x1d05;-rutinoside were isolated for the first time from the investigated taxon. In addition, the antioxidant activities in different tests of all obtained compounds were evaluated. The results clearly showed that among analyzed constituents, quercetin 3-O-beta-& x1d05;-glucoside exhibited antioxidant activity comparable or better than ascorbic acid and Trolox which were used as a positive control.

  DOI：

  10.1080/14786419.2018.1499644
• 作为产物：
  描述：

  圣草酚 、 alkaline earth salt of/the/ methylsulfuric acid 以 二甲基亚砜 为溶剂， 反应 168.0h， 以30%的产率得到圣草酚-7-O-葡糖苷
  参考文献：
  名称：

  球孢球孢白僵菌，非洲黑麦草和非洲黑麦草对类黄酮的区域选择性O-糖基化作用。

  摘要：

  在本研究中，物种：白僵菌，蓝色犁头霉和灰绿犁头霉在黄酮（白杨素，芹菜素，木犀草素，香叶木素）和黄烷酮（松属素，柚皮素，圣草酚，橙皮素）的生物转化中使用。该球孢白僵菌AM 278应变催化的甲基葡萄糖附着反应以类黄酮分子在位置C7和C3'。利用Absidia属（A. coerulea AM 93，A。glauca AM 177）作为生物催化剂可导致在类黄酮骨架的C7和C3'位置上形成带有糖分子的糖苷。先前没有文献报道九种获得的产品。

  DOI：

  10.1016/j.bioorg.2019.01.046

文献信息

• Low-emulsifier or emulsifier-free systems of the oil-in-water type with a content of stabilizers and an amino-substituted hydroxybenzophenone
  申请人：——

  公开号：US20030124158A1

  公开（公告）日：2003-07-03

  Cosmetic or dermatological preparations which represent finely disperse systems of the oil-in-water type, comprising a) an oil phase, b) a water phase, c) one or more stabilizers, d) at most 2.00% by weight of one or more emulsifiers, and e) an amino-substituted hydroxybenzophenone of the formula I 1

  化妆品或皮肤科制剂，代表油包水型的细分散系统，包括 a) 油相， b) 水相， c) 一种或多种稳定剂， d) 最多占总重量的2.00%的一种或多种乳化剂，以及 e) 公式I的氨基取代羟基苯酮 1
• ANTIOXIDANT MATERIAL, ANTI-DETERIORATION AGENT AND FOOD OR BEVERAGE
  申请人：POKKA CORPORATION

  公开号：EP1783193A1

  公开（公告）日：2007-05-09

  An antioxidant material of the present invention contains flavonoid aglycon and vitamin C. The flavonoid aglycon is eriodictyol and/or diosmetin obtained by treatment of a raw material containing flavonoid glycoside derived from lemons, limes, or sudachis to form the aglycones thereof. It is preferred that this antioxidant material be produced through a step of mixing the flavonoid aglycon and the vitamin C after the treatment to form the aglycones. The treatment to form the aglycones is glycosidase treatment using a β-glycosidase derived from a microorganism of the genus Aspergillus or Penicillium multicolor, or microbial fermentative treatment using a microorganism of the genus Aspergillus. An anti-deterioration agent and a food or beverage of the present invention contain the antioxidant material.

  本发明的一种抗氧化剂材料含有黄酮苷元和维生素 C。黄酮苷元是通过处理从柠檬、酸橙或苏打树提取的含有黄酮苷元的原料以形成其苷元而获得的二碘酪醇（eriodictyol）和/或二锇醇（diosmetin）。这种抗氧化剂材料最好是在处理形成苷元后，通过将黄酮苷元和维生素 C 混合的步骤生产出来。形成苷元的处理方法是使用从曲霉属或多色青霉属微生物中提取的β-糖苷酶进行糖苷酶处理，或使用曲霉属微生物进行微生物发酵处理。本发明的抗变质剂和食品或饮料含有抗氧化材料。
• METHOD FOR PRODUCING FLAVONOID CLATHRATE
  申请人：Taiyo Kagaku Co., Ltd.

  公开号：EP3453766A1

  公开（公告）日：2019-03-13

  A method for producing a flavonoid inclusion compound, including a cleaving step including treating a sparingly soluble flavonoid having a rhamnoside structure with an enzyme having a rhamnosidase activity in the presence of a cyclodextrin to cleave a rhamnose. According to the production method of the present invention, a flavonoid inclusion compound and a composition of flavonoid glycosides having excellent solubility in water can be efficiently produced, so that the compound and composition can be suitably utilized in the fields of medicaments, foodstuff, health foods, foods for specified health use, cosmetics, and the like.

  一种生产类黄酮包合物的方法，包括裂解步骤，该步骤包括在环糊精存在下，用具有鼠李糖酶活性的酶处理具有鼠李糖苷结构的稀溶性类黄酮，以裂解鼠李糖。根据本发明的生产方法，可以有效地生产出在水中具有良好溶解性的黄酮类包合物和黄酮苷组合物，从而可以将该化合物和组合物适当地用于药物、食品、保健食品、特定保健用食品、化妆品等领域。
• FLAVONOID INCLUSION COMPOUNDS
  申请人：Taiyo Kagaku Co., Ltd.

  公开号：EP3733860A1

  公开（公告）日：2020-11-04

  The present invention comprises a flavonoid inclusion compound which is an inclusion compound of a flavonoid without rhamnoside structure and a cyclic oligosaccharide selected from cyclodextrin, cyclodextran, cyclofructan, cycloalteman, and cluster dextrin, wherein the flavonoid portion has a solubility in water of 2% or more at 25°C.

  本发明包括一种类黄酮包合物，它是一种不含鼠李糖苷结构的类黄酮和环状寡糖的包合物，环状寡糖选自环糊精、环葡聚糖、环果糖、环麦芽糖和簇状糊精，其中类黄酮部分在 25°C 时在水中的溶解度为 2% 或以上。
• COMPOSITION CONTAINING FLAVONOID-CYCLODEXTRIN CLATHRATE COMPOUND
  申请人：Taiyo Kagaku Co., Ltd.

  公开号：EP3805399A1

  公开（公告）日：2021-04-14

  A composition containing one or more materials selected from the group consisting of fatty acids, proteins, peptides, amino acids, vitamins, minerals, alcohols, sweeteners, acidulants, antioxidants, thickening stabilizer, and surfactants, and a flavonoid-cyclodextrin inclusion compound, wherein the inclusion compound contains an inclusion compound obtained by treating a flavonoid having a rhamnoside structure with an enzyme having rhamnosidase activity in the presence of a cyclodextrin. According to the present invention, the bitterness and the changes in color tones originated from flavonoids can be inhibited, and foodstuff or the like having an unpleasant taste can be improved, so that the present invention can be suitably utilized in fields such as medicaments, foodstuff, health foods, foods for specified health use, and cosmetics.

  一种组合物，含有选自由脂肪酸、蛋白质、肽、氨基酸、维生素、矿物质、醇、甜味剂、酸味剂、抗氧化剂、增稠稳定剂和表面活性剂组成的组中的一种或多种材料，以及黄酮类化合物-环糊精包合物，其中包合物含有通过在环糊精存在下用具有鼠李糖酶活性的酶处理具有鼠李糖苷结构的黄酮类化合物而获得的包合物。根据本发明，可以抑制由黄酮类化合物产生的苦味和色调变化，改善食品等的异味，因此本发明可以适当地应用于药物、食品、保健食品、特定保健用食品和化妆品等领域。