| 211820-63-2

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 有机碘化物
• CAS: 211820-63-2
• 化学式: C₁₀H₁₅I
• 分子量: 262.134
• InChiKey: JDILIBAKOPFZHE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  11.0
• 可旋转键数：
  1.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  0.0
• 氢给体数：
  0.0
• 氢受体数：
  0.0

反应信息

• 作为反应物：
  描述：

  在 (C₅Me₅)2YCH₃*THF 咪唑 、 六甲基磷酰三胺 、 potassium tert-butylate 、 二异丁基氢化铝 、 lithium diisopropyl amide 作用下， 以 环己烷 、 N,N-二甲基甲酰胺 为溶剂， 生成
  参考文献：
  名称：

  Sequential Cyclization/Silylation of Dienynes Catalyzed by an Organoyttrium Complex

  摘要：

  The organoyttrium complex Cp*2YCH3. THF (Cp* = C5Me5) has been shown to be an effective precatalyst for the selective sequential cyclization/silylation of dienynes. The catalyst's ability to insert the alkyne in preference to the alkenes in a regioselective manner, combined with the high diastereoselectivity of the intramolecular insertion process, leads to bicyclo[3.3.0]octane products in high yield. The stereochemistry of the exocyclic olefin, the ring fusion, and the ring substituents are all controlled in the reaction. The cyclization of dienynes thus affords silylated carbobicyclics with high diastereoselectivities in excellent yields.

  DOI：

  10.1021/jo980521t
• 作为产物：
  描述：

  tert-Butyl-(4-cyclohexyl-but-3-ynyloxy)-dimethyl-silane 在 咪唑 、 四丁基氟化铵 、 碘 、 三苯基膦 作用下， 以 四氢呋喃 、 乙醚 、 乙腈 为溶剂， 生成
  参考文献：
  名称：

  Sequential Cyclization/Silylation of Dienynes Catalyzed by an Organoyttrium Complex

  摘要：

  The organoyttrium complex Cp*2YCH3. THF (Cp* = C5Me5) has been shown to be an effective precatalyst for the selective sequential cyclization/silylation of dienynes. The catalyst's ability to insert the alkyne in preference to the alkenes in a regioselective manner, combined with the high diastereoselectivity of the intramolecular insertion process, leads to bicyclo[3.3.0]octane products in high yield. The stereochemistry of the exocyclic olefin, the ring fusion, and the ring substituents are all controlled in the reaction. The cyclization of dienynes thus affords silylated carbobicyclics with high diastereoselectivities in excellent yields.

  DOI：

  10.1021/jo980521t