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    —— ethyl (6S)-6-methyl-2-[[(5R,7R)-5-thiophen-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-2-carbonyl]amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate —— C24H25F3N4O3S2
    ethyl (6S)-6-methyl-2-[[(5R,7R)-5-thiophen-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-2-carbonyl]amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate
    —— ethyl (3R)-1-[4-(1,3-benzodioxole-5-carbonylamino)-2-[[(1S)-1-phenylethyl]sulfamoyl]phenyl]piperidine-3-carboxylate —— C30H33N3O7S
    ethyl (3R)-1-[4-(1,3-benzodioxole-5-carbonylamino)-2-[[(1S)-1-phenylethyl]sulfamoyl]phenyl]piperidine-3-carboxylate
    —— ethyl 1-[2-[[(3-phenoxyphenyl)methyl-[(1S)-1-phenylethyl]amino]methyl]-1,3-oxazole-4-carbonyl]piperidine-4-carboxylate —— C34H37N3O5
    ethyl 1-[2-[[(3-phenoxyphenyl)methyl-[(1S)-1-phenylethyl]amino]methyl]-1,3-oxazole-4-carbonyl]piperidine-4-carboxylate
    —— ethyl (4S)-2-oxo-4-thiophen-2-yl-6-[[5-[3-(trifluoromethyl)phenyl]furan-2-carbonyl]oxymethyl]-3,4-dihydro-1H-pyrimidine-5-carboxylate —— C24H19F3N2O6S
    ethyl (4S)-2-oxo-4-thiophen-2-yl-6-[[5-[3-(trifluoromethyl)phenyl]furan-2-carbonyl]oxymethyl]-3,4-dihydro-1H-pyrimidine-5-carboxylate
    —— ethyl 1-[2-[[(3-phenoxyphenyl)methyl-[(1R)-1-phenylethyl]amino]methyl]-1,3-oxazole-4-carbonyl]piperidine-4-carboxylate —— C34H37N3O5
    ethyl 1-[2-[[(3-phenoxyphenyl)methyl-[(1R)-1-phenylethyl]amino]methyl]-1,3-oxazole-4-carbonyl]piperidine-4-carboxylate
    —— ethyl (4R)-2-oxo-4-thiophen-2-yl-6-[[5-[3-(trifluoromethyl)phenyl]furan-2-carbonyl]oxymethyl]-3,4-dihydro-1H-pyrimidine-5-carboxylate —— C24H19F3N2O6S
    ethyl (4R)-2-oxo-4-thiophen-2-yl-6-[[5-[3-(trifluoromethyl)phenyl]furan-2-carbonyl]oxymethyl]-3,4-dihydro-1H-pyrimidine-5-carboxylate
    —— ethyl 3-[(1R,8S,15R,19R)-4,11-ditert-butyl-16,18-dioxo-17-azapentacyclo[6.6.5.02,7.09,14.015,19]nonadeca-2(7),3,5,9(14),10,12-hexaen-17-yl]benzoate —— C35H37NO4
    ethyl 3-[(1R,8S,15R,19R)-4,11-ditert-butyl-16,18-dioxo-17-azapentacyclo[6.6.5.02,7.09,14.015,19]nonadeca-2(7),3,5,9(14),10,12-hexaen-17-yl]benzoate
    —— (E)-2-cyano-3-[1-(furan-2-ylmethyl)-2,5-dimethylpyrrol-3-yl]-N-(2,4,6-trimethylphenyl)prop-2-enamide —— C24H25N3O2
    (E)-2-cyano-3-[1-(furan-2-ylmethyl)-2,5-dimethylpyrrol-3-yl]-N-(2,4,6-trimethylphenyl)prop-2-enamide
    —— (E)-N-(4-chloro-2-methoxy-5-methylphenyl)-2-cyano-3-(4-cyanophenyl)prop-2-enamide —— C19H14ClN3O2
    (E)-N-(4-chloro-2-methoxy-5-methylphenyl)-2-cyano-3-(4-cyanophenyl)prop-2-enamide
    —— (E)-2-cyano-3-(2,5-dimethyl-1-naphthalen-1-ylpyrrol-3-yl)-N-[[(2S)-oxolan-2-yl]methyl]prop-2-enamide —— C25H25N3O2
    (E)-2-cyano-3-(2,5-dimethyl-1-naphthalen-1-ylpyrrol-3-yl)-N-[[(2S)-oxolan-2-yl]methyl]prop-2-enamide
    —— (E)-2-cyano-3-(4-hydroxy-3,5-dimethylphenyl)-N-[(1R,2R)-2-methylcyclohexyl]prop-2-enamide —— C19H24N2O2
    (E)-2-cyano-3-(4-hydroxy-3,5-dimethylphenyl)-N-[(1R,2R)-2-methylcyclohexyl]prop-2-enamide
    —— (E)-2-cyano-3-(3-methoxy-4-propoxyphenyl)-N-[(1R,2R)-2-methylcyclohexyl]prop-2-enamide —— C21H28N2O3
    (E)-2-cyano-3-(3-methoxy-4-propoxyphenyl)-N-[(1R,2R)-2-methylcyclohexyl]prop-2-enamide
    —— ethyl 3-[(1R,8S,15S,19R)-4,11-ditert-butyl-16,18-dioxo-17-azapentacyclo[6.6.5.02,7.09,14.015,19]nonadeca-2(7),3,5,9(14),10,12-hexaen-17-yl]benzoate —— C35H37NO4
    ethyl 3-[(1R,8S,15S,19R)-4,11-ditert-butyl-16,18-dioxo-17-azapentacyclo[6.6.5.02,7.09,14.015,19]nonadeca-2(7),3,5,9(14),10,12-hexaen-17-yl]benzoate
    —— (E)-3-(1-benzyl-3-pyridin-3-ylpyrazol-4-yl)-2-cyano-N-[(1R,2S)-2-methylcyclohexyl]prop-2-enamide —— C26H27N5O
    (E)-3-(1-benzyl-3-pyridin-3-ylpyrazol-4-yl)-2-cyano-N-[(1R,2S)-2-methylcyclohexyl]prop-2-enamide
    —— (E)-N-(4-chloro-2-methoxy-5-methylphenyl)-2-cyano-3-(3-methoxy-2-propan-2-yloxyphenyl)prop-2-enamide —— C22H23ClN2O4
    (E)-N-(4-chloro-2-methoxy-5-methylphenyl)-2-cyano-3-(3-methoxy-2-propan-2-yloxyphenyl)prop-2-enamide
    —— (E)-2-cyano-N-(2,4-dimethylphenyl)-3-(4-fluorophenyl)prop-2-enamide —— C18H15FN2O
    (E)-2-cyano-N-(2,4-dimethylphenyl)-3-(4-fluorophenyl)prop-2-enamide
    —— (E)-2-cyano-3-[3-(difluoromethoxy)-4-methoxyphenyl]-N-(3-methylphenyl)prop-2-enamide —— C19H16F2N2O3
    (E)-2-cyano-3-[3-(difluoromethoxy)-4-methoxyphenyl]-N-(3-methylphenyl)prop-2-enamide
    —— (E)-3-(3-chloro-5-ethoxy-4-propoxyphenyl)-2-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)prop-2-enenitrile —— C21H25ClN4O2
    (E)-3-(3-chloro-5-ethoxy-4-propoxyphenyl)-2-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)prop-2-enenitrile
    —— (E)-2-cyano-3-(furan-2-yl)-N-[(1S,2S)-2-methylcyclohexyl]prop-2-enamide —— C15H18N2O2
    (E)-2-cyano-3-(furan-2-yl)-N-[(1S,2S)-2-methylcyclohexyl]prop-2-enamide
    —— ethyl (6S)-6-methyl-2-[[(5R,7S)-5-thiophen-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-2-carbonyl]amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate —— C24H25F3N4O3S2
    ethyl (6S)-6-methyl-2-[[(5R,7S)-5-thiophen-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-2-carbonyl]amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate
    —— (E)-3-(5-bromo-2-fluorophenyl)-2-cyano-N-(2,4,6-trimethylphenyl)prop-2-enamide —— C19H16BrFN2O
    (E)-3-(5-bromo-2-fluorophenyl)-2-cyano-N-(2,4,6-trimethylphenyl)prop-2-enamide
    —— (E)-N-(4-butylphenyl)-2-cyano-3-pyridin-4-ylprop-2-enamide —— C19H19N3O
    (E)-N-(4-butylphenyl)-2-cyano-3-pyridin-4-ylprop-2-enamide
    —— (E)-2-cyano-N-(2,5-dichlorophenyl)-3-(3-methoxy-2-propan-2-yloxyphenyl)prop-2-enamide —— C20H18Cl2N2O3
    (E)-2-cyano-N-(2,5-dichlorophenyl)-3-(3-methoxy-2-propan-2-yloxyphenyl)prop-2-enamide
    —— (E)-2-cyano-3-(4-cyanophenyl)-N-(2-phenoxyphenyl)prop-2-enamide —— C23H15N3O2
    (E)-2-cyano-3-(4-cyanophenyl)-N-(2-phenoxyphenyl)prop-2-enamide
    —— (E)-3-(4-bromothiophen-2-yl)-2-cyano-N-(3-methylphenyl)prop-2-enamide —— C15H11BrN2OS
    (E)-3-(4-bromothiophen-2-yl)-2-cyano-N-(3-methylphenyl)prop-2-enamide
    —— (E)-2-cyano-3-[4-[ethyl(2-hydroxyethyl)amino]-2-methylphenyl]-N-(3-methylphenyl)prop-2-enamide —— C22H25N3O2
    (E)-2-cyano-3-[4-[ethyl(2-hydroxyethyl)amino]-2-methylphenyl]-N-(3-methylphenyl)prop-2-enamide
    —— (E)-3-[5-(4-chloro-2-nitrophenyl)furan-2-yl]-2-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)prop-2-enenitrile —— C20H16ClN5O3
    (E)-3-[5-(4-chloro-2-nitrophenyl)furan-2-yl]-2-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)prop-2-enenitrile
    —— (E)-3-(4-bromophenyl)-N-(2-chlorophenyl)-2-cyanoprop-2-enamide —— C16H10BrClN2O
    (E)-3-(4-bromophenyl)-N-(2-chlorophenyl)-2-cyanoprop-2-enamide
    —— (E)-3-(3,5-dimethoxyphenyl)-2-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)prop-2-enenitrile —— C18H20N4O2
    (E)-3-(3,5-dimethoxyphenyl)-2-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)prop-2-enenitrile
    —— (E)-3-[3-chloro-4-(difluoromethoxy)-5-methoxyphenyl]-2-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)prop-2-enenitrile —— C18H17ClF2N4O2
    (E)-3-[3-chloro-4-(difluoromethoxy)-5-methoxyphenyl]-2-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)prop-2-enenitrile
    —— (E)-2-cyano-3-(4-methoxy-3-propoxyphenyl)-N-[(1R,2R)-2-methylcyclohexyl]prop-2-enamide —— C21H28N2O3
    (E)-2-cyano-3-(4-methoxy-3-propoxyphenyl)-N-[(1R,2R)-2-methylcyclohexyl]prop-2-enamide
    —— (E)-3-[2-(N-acetylanilino)-1,3-thiazol-4-yl]-2-cyano-N-(3-methylphenyl)prop-2-enamide —— C22H18N4O2S
    (E)-3-[2-(N-acetylanilino)-1,3-thiazol-4-yl]-2-cyano-N-(3-methylphenyl)prop-2-enamide
    —— (E)-3-(2-chloro-6-fluorophenyl)-2-cyano-N-[(1R,2R)-2-methylcyclohexyl]prop-2-enamide —— C17H18ClFN2O
    (E)-3-(2-chloro-6-fluorophenyl)-2-cyano-N-[(1R,2R)-2-methylcyclohexyl]prop-2-enamide
    —— (E)-3-(4-bromothiophen-2-yl)-2-cyano-N-[(1R,2S)-2-methylcyclohexyl]prop-2-enamide —— C15H17BrN2OS
    (E)-3-(4-bromothiophen-2-yl)-2-cyano-N-[(1R,2S)-2-methylcyclohexyl]prop-2-enamide
    —— ethyl (4S)-6-[[(Z)-3-[5-chloro-1-(4-fluorophenyl)-3-methylpyrazol-4-yl]prop-2-enoyl]oxymethyl]-2-oxo-4-phenyl-3,4-dihydro-1H-pyrimidine-5-carboxylate —— C27H24ClFN4O5
    ethyl (4S)-6-[[(Z)-3-[5-chloro-1-(4-fluorophenyl)-3-methylpyrazol-4-yl]prop-2-enoyl]oxymethyl]-2-oxo-4-phenyl-3,4-dihydro-1H-pyrimidine-5-carboxylate
    —— (E)-N-(4-butylphenyl)-2-cyano-3-(2-methoxyphenyl)prop-2-enamide —— C21H22N2O2
    (E)-N-(4-butylphenyl)-2-cyano-3-(2-methoxyphenyl)prop-2-enamide
    —— (E)-2-cyano-3-[4-[2-(ethylamino)-2-oxoethoxy]-3-methoxyphenyl]-N-[(1S,2S)-2-methylcyclohexyl]prop-2-enamide —— C22H29N3O4
    (E)-2-cyano-3-[4-[2-(ethylamino)-2-oxoethoxy]-3-methoxyphenyl]-N-[(1S,2S)-2-methylcyclohexyl]prop-2-enamide
    —— (E)-2-cyano-3-(7-ethyl-1H-indol-3-yl)-N-[(1S,2S)-2-methylcyclohexyl]prop-2-enamide —— C21H25N3O
    (E)-2-cyano-3-(7-ethyl-1H-indol-3-yl)-N-[(1S,2S)-2-methylcyclohexyl]prop-2-enamide
    —— (E)-3-(3-chloro-5-ethoxy-4-hydroxyphenyl)-N-(2-chlorophenyl)-2-cyanoprop-2-enamide —— C18H14Cl2N2O3
    (E)-3-(3-chloro-5-ethoxy-4-hydroxyphenyl)-N-(2-chlorophenyl)-2-cyanoprop-2-enamide
    —— (E)-3-(2-bromo-5-hydroxy-4-methoxyphenyl)-2-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)prop-2-enenitrile —— C17H17BrN4O2
    (E)-3-(2-bromo-5-hydroxy-4-methoxyphenyl)-2-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)prop-2-enenitrile
    —— ethyl 5-amino-3-[[(2S)-2-(4-chlorophenoxy)propanoyl]oxymethyl]-4-cyanothiophene-2-carboxylate —— C18H17ClN2O5S
    ethyl 5-amino-3-[[(2S)-2-(4-chlorophenoxy)propanoyl]oxymethyl]-4-cyanothiophene-2-carboxylate
    —— (E)-2-cyano-3-(3,5-dibromo-2-ethoxyphenyl)-N-prop-2-enylprop-2-enamide —— C15H14Br2N2O2
    (E)-2-cyano-3-(3,5-dibromo-2-ethoxyphenyl)-N-prop-2-enylprop-2-enamide
    —— (E)-2-cyano-3-(4-cyanophenyl)-N-(2-phenylethyl)prop-2-enamide —— C19H15N3O
    (E)-2-cyano-3-(4-cyanophenyl)-N-(2-phenylethyl)prop-2-enamide
    —— (E)-3-(6-bromo-1,3-benzodioxol-5-yl)-2-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)prop-2-enenitrile —— C17H15BrN4O2
    (E)-3-(6-bromo-1,3-benzodioxol-5-yl)-2-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)prop-2-enenitrile
    —— (E)-2-cyano-N-(2-ethoxyphenyl)-3-(3-methoxy-2-propan-2-yloxyphenyl)prop-2-enamide —— C22H24N2O4
    (E)-2-cyano-N-(2-ethoxyphenyl)-3-(3-methoxy-2-propan-2-yloxyphenyl)prop-2-enamide
    —— (E)-3-(2-chloro-8-methylquinolin-3-yl)-2-cyano-N-(2,4,6-trimethylphenyl)prop-2-enamide —— C23H20ClN3O
    (E)-3-(2-chloro-8-methylquinolin-3-yl)-2-cyano-N-(2,4,6-trimethylphenyl)prop-2-enamide
    —— (E)-3-(5-bromothiophen-2-yl)-N-(4-chloro-2-methoxy-5-methylphenyl)-2-cyanoprop-2-enamide —— C16H12BrClN2O2S
    (E)-3-(5-bromothiophen-2-yl)-N-(4-chloro-2-methoxy-5-methylphenyl)-2-cyanoprop-2-enamide
    —— (E)-3-(2-bromo-4,5-dimethoxyphenyl)-2-cyano-N-(2-phenylethyl)prop-2-enamide —— C20H19BrN2O3
    (E)-3-(2-bromo-4,5-dimethoxyphenyl)-2-cyano-N-(2-phenylethyl)prop-2-enamide
    —— (E)-3-(2-chloro-6-methoxyquinolin-3-yl)-2-cyano-N-[(1S,2R)-2-methylcyclohexyl]prop-2-enamide —— C21H22ClN3O2
    (E)-3-(2-chloro-6-methoxyquinolin-3-yl)-2-cyano-N-[(1S,2R)-2-methylcyclohexyl]prop-2-enamide
    —— (E)-2-cyano-3-(4-hydroxy-3-nitrophenyl)-N-[(1R,2S)-2-methylcyclohexyl]prop-2-enamide —— C17H19N3O4
    (E)-2-cyano-3-(4-hydroxy-3-nitrophenyl)-N-[(1R,2S)-2-methylcyclohexyl]prop-2-enamide