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    —— (5R,6S)-5-(4-bromophenyl)-2-[(3S)-3-methylpiperidin-1-yl]-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C20H20BrN5O2
    (5R,6S)-5-(4-bromophenyl)-2-[(3S)-3-methylpiperidin-1-yl]-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5S,6R)-2-(4-benzylpiperidin-1-yl)-5-(2-fluorophenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C26H24FN5O2
    (5S,6R)-2-(4-benzylpiperidin-1-yl)-5-(2-fluorophenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5R,6R)-2-(4-benzylpiperidin-1-yl)-5-(3-methylphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C27H27N5O2
    (5R,6R)-2-(4-benzylpiperidin-1-yl)-5-(3-methylphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5S,6R)-2-(4-benzylpiperidin-1-yl)-5-(4-methylsulfanylphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C27H27N5O2S
    (5S,6R)-2-(4-benzylpiperidin-1-yl)-5-(4-methylsulfanylphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5R,6R)-2-(4-benzylpiperidin-1-yl)-5-(3-ethoxyphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C28H29N5O3
    (5R,6R)-2-(4-benzylpiperidin-1-yl)-5-(3-ethoxyphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5R,6R)-2-(4-benzylpiperidin-1-yl)-5-(4-methylsulfanylphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C27H27N5O2S
    (5R,6R)-2-(4-benzylpiperidin-1-yl)-5-(4-methylsulfanylphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5R,6R)-2-(4-benzylpiperidin-1-yl)-5-(3,4-dimethoxyphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C28H29N5O4
    (5R,6R)-2-(4-benzylpiperidin-1-yl)-5-(3,4-dimethoxyphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5R,6S)-2-(4-benzylpiperidin-1-yl)-5-(2-methoxyphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C27H27N5O3
    (5R,6S)-2-(4-benzylpiperidin-1-yl)-5-(2-methoxyphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5S,6S)-2-(4-benzylpiperidin-1-yl)-5-(4-methylphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C27H27N5O2
    (5S,6S)-2-(4-benzylpiperidin-1-yl)-5-(4-methylphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5R,6S)-2-(4-benzylpiperidin-1-yl)-5-(4-ethoxyphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C28H29N5O3
    (5R,6S)-2-(4-benzylpiperidin-1-yl)-5-(4-ethoxyphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5R,6S)-2-(4-benzylpiperidin-1-yl)-4,7-dioxo-5-pyridin-3-yl-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C25H24N6O2
    (5R,6S)-2-(4-benzylpiperidin-1-yl)-4,7-dioxo-5-pyridin-3-yl-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5S,6R)-2-(4-methylpiperidin-1-yl)-4,7-dioxo-5-phenyl-3,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C20H21N5O2
    (5S,6R)-2-(4-methylpiperidin-1-yl)-4,7-dioxo-5-phenyl-3,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5S,6S)-5-(2,4-dimethoxyphenyl)-2-(4-methylpiperidin-1-yl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C22H25N5O4
    (5S,6S)-5-(2,4-dimethoxyphenyl)-2-(4-methylpiperidin-1-yl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5S,6R)-2-(4-benzylpiperidin-1-yl)-5-(3-methoxyphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C27H27N5O3
    (5S,6R)-2-(4-benzylpiperidin-1-yl)-5-(3-methoxyphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5R,6S)-2-(4-benzylpiperidin-1-yl)-5-(3-bromophenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C26H24BrN5O2
    (5R,6S)-2-(4-benzylpiperidin-1-yl)-5-(3-bromophenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5S,6R)-2-(4-benzylpiperidin-1-yl)-5-(2-chloro-6-fluorophenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C26H23ClFN5O2
    (5S,6R)-2-(4-benzylpiperidin-1-yl)-5-(2-chloro-6-fluorophenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5R,6S)-2-(4-benzylpiperidin-1-yl)-5-(3-chlorophenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C26H24ClN5O2
    (5R,6S)-2-(4-benzylpiperidin-1-yl)-5-(3-chlorophenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5R,6S)-2-(4-benzylpiperidin-1-yl)-5-(3-nitrophenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C26H24N6O4
    (5R,6S)-2-(4-benzylpiperidin-1-yl)-5-(3-nitrophenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5R,6S)-2-(4-benzylpiperidin-1-yl)-5-[4-(2-methylpropyl)phenyl]-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C30H33N5O2
    (5R,6S)-2-(4-benzylpiperidin-1-yl)-5-[4-(2-methylpropyl)phenyl]-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— [5-(Furan-2-yl)-1,2-oxazol-3-yl]methyl 4-(methylamino)-3-nitrobenzoate —— C16H13N3O6
    [5-(Furan-2-yl)-1,2-oxazol-3-yl]methyl 4-(methylamino)-3-nitrobenzoate
    —— (5S,6S)-2-(4-benzylpiperidin-1-yl)-5-(2-chloro-6-fluorophenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C26H23ClFN5O2
    (5S,6S)-2-(4-benzylpiperidin-1-yl)-5-(2-chloro-6-fluorophenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5R,6R)-2-(4-benzylpiperidin-1-yl)-5-(3-nitrophenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C26H24N6O4
    (5R,6R)-2-(4-benzylpiperidin-1-yl)-5-(3-nitrophenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5R,6S)-2-(4-benzylpiperidin-1-yl)-4,7-dioxo-5-pyridin-4-yl-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C25H24N6O2
    (5R,6S)-2-(4-benzylpiperidin-1-yl)-4,7-dioxo-5-pyridin-4-yl-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5S,6S)-2-(4-benzylpiperidin-1-yl)-4,7-dioxo-5-[(E)-2-phenylethenyl]-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C28H27N5O2
    (5S,6S)-2-(4-benzylpiperidin-1-yl)-4,7-dioxo-5-[(E)-2-phenylethenyl]-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5R,6R)-2-(4-benzylpiperidin-1-yl)-5-(4-ethoxyphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C28H29N5O3
    (5R,6R)-2-(4-benzylpiperidin-1-yl)-5-(4-ethoxyphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5R,6R)-2-(4-benzylpiperidin-1-yl)-5-[4-(2-methylpropyl)phenyl]-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C30H33N5O2
    (5R,6R)-2-(4-benzylpiperidin-1-yl)-5-[4-(2-methylpropyl)phenyl]-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5R,6S)-2-(4-benzylpiperidin-1-yl)-5-(4-chlorophenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C26H24ClN5O2
    (5R,6S)-2-(4-benzylpiperidin-1-yl)-5-(4-chlorophenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5S,6S)-2-(4-benzylpiperidin-1-yl)-5-(4-ethylphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C28H29N5O2
    (5S,6S)-2-(4-benzylpiperidin-1-yl)-5-(4-ethylphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5S,6R)-2-(4-benzylpiperidin-1-yl)-5-(3,5-difluorophenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C26H23F2N5O2
    (5S,6R)-2-(4-benzylpiperidin-1-yl)-5-(3,5-difluorophenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5S,6S)-2-(4-benzylpiperidin-1-yl)-4,7-dioxo-5-(4-propan-2-ylphenyl)-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C29H31N5O2
    (5S,6S)-2-(4-benzylpiperidin-1-yl)-4,7-dioxo-5-(4-propan-2-ylphenyl)-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5R,6S)-5-[4-(diethylamino)phenyl]-2-[(3S)-3-methylpiperidin-1-yl]-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C24H30N6O2
    (5R,6S)-5-[4-(diethylamino)phenyl]-2-[(3S)-3-methylpiperidin-1-yl]-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5S,6R)-2-(4-methylpiperidin-1-yl)-5-(3-nitrophenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C20H20N6O4
    (5S,6R)-2-(4-methylpiperidin-1-yl)-5-(3-nitrophenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5R,6S)-2-(4-benzylpiperidin-1-yl)-4,7-dioxo-5-(2,4,5-trimethoxyphenyl)-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C29H31N5O5
    (5R,6S)-2-(4-benzylpiperidin-1-yl)-4,7-dioxo-5-(2,4,5-trimethoxyphenyl)-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5S,6R)-2-(4-benzylpiperidin-1-yl)-4,7-dioxo-5-(2-prop-2-enoxyphenyl)-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C29H29N5O3
    (5S,6R)-2-(4-benzylpiperidin-1-yl)-4,7-dioxo-5-(2-prop-2-enoxyphenyl)-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5R,6S)-2-(4-benzylpiperidin-1-yl)-5-(3-methylphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C27H27N5O2
    (5R,6S)-2-(4-benzylpiperidin-1-yl)-5-(3-methylphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5S,6R)-2-(4-benzylpiperidin-1-yl)-4,7-dioxo-5-pyridin-2-yl-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C25H24N6O2
    (5S,6R)-2-(4-benzylpiperidin-1-yl)-4,7-dioxo-5-pyridin-2-yl-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5S,6S)-2-(4-benzylpiperidin-1-yl)-5-(4-methoxyphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C27H27N5O3
    (5S,6S)-2-(4-benzylpiperidin-1-yl)-5-(4-methoxyphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5S,6S)-2-(4-benzylpiperidin-1-yl)-5-(3-methylphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C27H27N5O2
    (5S,6S)-2-(4-benzylpiperidin-1-yl)-5-(3-methylphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5R,6S)-2-(4-benzylpiperidin-1-yl)-5-(4-methylsulfanylphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C27H27N5O2S
    (5R,6S)-2-(4-benzylpiperidin-1-yl)-5-(4-methylsulfanylphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5R,6R)-2-(4-benzylpiperidin-1-yl)-5-(3-chlorophenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C26H24ClN5O2
    (5R,6R)-2-(4-benzylpiperidin-1-yl)-5-(3-chlorophenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5S,6R)-2-(4-benzylpiperidin-1-yl)-5-(4-nitrophenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C26H24N6O4
    (5S,6R)-2-(4-benzylpiperidin-1-yl)-5-(4-nitrophenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5S,6R)-2-(4-benzylpiperidin-1-yl)-5-(3,4-dimethoxyphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C28H29N5O4
    (5S,6R)-2-(4-benzylpiperidin-1-yl)-5-(3,4-dimethoxyphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5R,6S)-2-(4-benzylpiperidin-1-yl)-5-(4-methylphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C27H27N5O2
    (5R,6S)-2-(4-benzylpiperidin-1-yl)-5-(4-methylphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5S,6R)-2-(4-benzylpiperidin-1-yl)-5-(2-chlorophenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C26H24ClN5O2
    (5S,6R)-2-(4-benzylpiperidin-1-yl)-5-(2-chlorophenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5S,6S)-2-(4-benzylpiperidin-1-yl)-5-(2-hydroxy-3-methoxyphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C27H27N5O4
    (5S,6S)-2-(4-benzylpiperidin-1-yl)-5-(2-hydroxy-3-methoxyphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5S,6R)-2-(4-benzylpiperidin-1-yl)-5-(3-methylphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C27H27N5O2
    (5S,6R)-2-(4-benzylpiperidin-1-yl)-5-(3-methylphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5S,6R)-2-(4-benzylpiperidin-1-yl)-4,7-dioxo-5-pyridin-3-yl-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C25H24N6O2
    (5S,6R)-2-(4-benzylpiperidin-1-yl)-4,7-dioxo-5-pyridin-3-yl-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5S,6S)-5-(2-hydroxynaphthalen-1-yl)-2-(4-methylpiperidin-1-yl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C24H23N5O3
    (5S,6S)-5-(2-hydroxynaphthalen-1-yl)-2-(4-methylpiperidin-1-yl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5S,6R)-2-(4-benzylpiperidin-1-yl)-5-[4-(2-methylpropyl)phenyl]-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C30H33N5O2
    (5S,6R)-2-(4-benzylpiperidin-1-yl)-5-[4-(2-methylpropyl)phenyl]-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5S,6S)-2-(4-benzylpiperidin-1-yl)-5-naphthalen-1-yl-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C30H27N5O2
    (5S,6S)-2-(4-benzylpiperidin-1-yl)-5-naphthalen-1-yl-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile