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    —— (5R,6R)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-5-(4-methoxyphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C24H21N5O5
    (5R,6R)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-5-(4-methoxyphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5S,6S)-5-(2-chloro-5-nitrophenyl)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C23H17ClN6O6
    (5S,6S)-5-(2-chloro-5-nitrophenyl)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5S,6S)-5-[4-(diethylamino)phenyl]-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C27H28N6O4
    (5S,6S)-5-[4-(diethylamino)phenyl]-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5S,6R)-2-(2,4-dichloroanilino)-5-(2,3-dihydro-1,4-benzodioxin-6-yl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C22H15Cl2N5O4
    (5S,6R)-2-(2,4-dichloroanilino)-5-(2,3-dihydro-1,4-benzodioxin-6-yl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5R,6S)-5-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[(3R,5S)-3,5-dimethylpiperidin-1-yl]-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C23H25N5O4
    (5R,6S)-5-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[(3R,5S)-3,5-dimethylpiperidin-1-yl]-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5R,6S)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-5-[4-(dimethylamino)phenyl]-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C25H24N6O4
    (5R,6S)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-5-[4-(dimethylamino)phenyl]-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5R,6R)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-5-(furan-2-yl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C21H17N5O5
    (5R,6R)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-5-(furan-2-yl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5S,6R)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-5-(2,3-dimethoxyphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C25H23N5O6
    (5S,6R)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-5-(2,3-dimethoxyphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5S,6S)-5-(2-chlorophenyl)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C23H18ClN5O4
    (5S,6S)-5-(2-chlorophenyl)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5R,6S)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-5-(2-hydroxynaphthalen-1-yl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C27H21N5O5
    (5R,6S)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-5-(2-hydroxynaphthalen-1-yl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5S,6S)-5-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C23H23N5O6
    (5S,6S)-5-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5S,6R)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-5-(4-ethylphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C25H23N5O4
    (5S,6R)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-5-(4-ethylphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5S,6S)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-5-[4-(dimethylamino)phenyl]-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C25H24N6O4
    (5S,6S)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-5-[4-(dimethylamino)phenyl]-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5S,6R)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-5-(2-ethoxyphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C25H23N5O5
    (5S,6R)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-5-(2-ethoxyphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5R,6R)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-4,7-dioxo-5-phenyl-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C23H19N5O4
    (5R,6R)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-4,7-dioxo-5-phenyl-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5R,6S)-5-[4-(diethylamino)phenyl]-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C27H28N6O4
    (5R,6S)-5-[4-(diethylamino)phenyl]-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5R,6S)-5-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[(3R,5R)-3,5-dimethylpiperidin-1-yl]-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C23H25N5O4
    (5R,6S)-5-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[(3R,5R)-3,5-dimethylpiperidin-1-yl]-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5S,6R)-5-(3-bromophenyl)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C23H18BrN5O4
    (5S,6R)-5-(3-bromophenyl)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5R,6R)-5-(2,3-dihydro-1,4-benzodioxin-6-yl)-4,7-dioxo-2-piperidin-1-yl-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C21H21N5O4
    (5R,6R)-5-(2,3-dihydro-1,4-benzodioxin-6-yl)-4,7-dioxo-2-piperidin-1-yl-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5S,6S)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-4,7-dioxo-5-(3-phenoxyphenyl)-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C29H23N5O5
    (5S,6S)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-4,7-dioxo-5-(3-phenoxyphenyl)-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5R,6S)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-5-(2-ethoxyphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C25H23N5O5
    (5R,6S)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-5-(2-ethoxyphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5S,6S)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-5-(4-hydroxy-3-methoxyphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C24H21N5O6
    (5S,6S)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-5-(4-hydroxy-3-methoxyphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5R,6S)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-5-(3-ethoxyphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C25H23N5O5
    (5R,6S)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-5-(3-ethoxyphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5S,6S)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-5-(2-hydroxynaphthalen-1-yl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C27H21N5O5
    (5S,6S)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-5-(2-hydroxynaphthalen-1-yl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5R,6R)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-5-(2-nitrophenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C23H18N6O6
    (5R,6R)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-5-(2-nitrophenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5S,6S)-5-(2,3-dihydro-1,4-benzodioxin-6-yl)-4,7-dioxo-2-piperidin-1-yl-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C21H21N5O4
    (5S,6S)-5-(2,3-dihydro-1,4-benzodioxin-6-yl)-4,7-dioxo-2-piperidin-1-yl-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5R,6R)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-5-(2-hydroxy-3-methoxyphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C24H21N5O6
    (5R,6R)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-5-(2-hydroxy-3-methoxyphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5R,6R)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-4,7-dioxo-5-(3,4,5-trimethoxyphenyl)-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C26H25N5O7
    (5R,6R)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-4,7-dioxo-5-(3,4,5-trimethoxyphenyl)-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5R,6S)-5-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[(2-methoxyphenyl)methylamino]-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C24H21N5O5
    (5R,6S)-5-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[(2-methoxyphenyl)methylamino]-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5S,6R)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-5-(2-hydroxy-3-methoxyphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C24H21N5O6
    (5S,6R)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-5-(2-hydroxy-3-methoxyphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5R,6R)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-5-(4-methylsulfanylphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C24H21N5O4S
    (5R,6R)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-5-(4-methylsulfanylphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5S,6R)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-5-(2-hydroxynaphthalen-1-yl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C27H21N5O5
    (5S,6R)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-5-(2-hydroxynaphthalen-1-yl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5S,6R)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-5-(2-fluorophenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C23H18FN5O4
    (5S,6R)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-5-(2-fluorophenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5S,6S)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-5-(3-methylthiophen-2-yl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C22H19N5O4S
    (5S,6S)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-5-(3-methylthiophen-2-yl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5S,6R)-5-(2,3-dihydro-1,4-benzodioxin-6-yl)-4,7-dioxo-2-piperidin-1-yl-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C21H21N5O4
    (5S,6R)-5-(2,3-dihydro-1,4-benzodioxin-6-yl)-4,7-dioxo-2-piperidin-1-yl-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5R,6R)-2-(4-benzylpiperidin-1-yl)-5-(2,3-dihydro-1,4-benzodioxin-6-yl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C28H27N5O4
    (5R,6R)-2-(4-benzylpiperidin-1-yl)-5-(2,3-dihydro-1,4-benzodioxin-6-yl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5R,6S)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-5-(1H-indol-3-yl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C25H20N6O4
    (5R,6S)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-5-(1H-indol-3-yl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5S,6R)-5-(3-chlorophenyl)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C23H18ClN5O4
    (5S,6R)-5-(3-chlorophenyl)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5S,6R)-5-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[(4-methoxyphenyl)methylamino]-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C24H21N5O5
    (5S,6R)-5-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[(4-methoxyphenyl)methylamino]-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5S,6S)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-5-(furan-2-yl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C21H17N5O5
    (5S,6S)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-5-(furan-2-yl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5R,6S)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-4,7-dioxo-5-(2-prop-2-enoxyphenyl)-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C26H23N5O5
    (5R,6S)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-4,7-dioxo-5-(2-prop-2-enoxyphenyl)-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5R,6S)-5-(2-chlorophenyl)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C23H18ClN5O4
    (5R,6S)-5-(2-chlorophenyl)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5R,6S)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-4,7-dioxo-5-pyridin-4-yl-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C22H18N6O4
    (5R,6S)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-4,7-dioxo-5-pyridin-4-yl-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5S,6S)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-5-(4-ethylphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C25H23N5O4
    (5S,6S)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-5-(4-ethylphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5R,6R)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-5-(2,5-dimethoxyphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C25H23N5O6
    (5R,6R)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-5-(2,5-dimethoxyphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5R,6R)-5-(2-chloro-6-fluorophenyl)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C23H17ClFN5O4
    (5R,6R)-5-(2-chloro-6-fluorophenyl)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5R,6S)-5-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C23H23N5O6
    (5R,6S)-5-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5S,6R)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-5-(3,4-dimethoxyphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C25H23N5O6
    (5S,6R)-2-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-5-(3,4-dimethoxyphenyl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5R,6S)-5-(2,3-dihydro-1,4-benzodioxin-6-yl)-4,7-dioxo-2-piperidin-1-yl-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C21H21N5O4
    (5R,6S)-5-(2,3-dihydro-1,4-benzodioxin-6-yl)-4,7-dioxo-2-piperidin-1-yl-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
    —— (5R,6S)-2-[(2-chlorophenyl)methylamino]-5-(2,3-dihydro-1,4-benzodioxin-6-yl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile —— C23H18ClN5O4
    (5R,6S)-2-[(2-chlorophenyl)methylamino]-5-(2,3-dihydro-1,4-benzodioxin-6-yl)-4,7-dioxo-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile