防治心绞痛药
心绞痛是冠状动脉粥样硬化性心脏病（冠心病）的一个重要临床症状。其主要原因是冠状动脉粥样硬化导致管腔狭窄，进而引起心肌血液供应不足，造成心肌供血与需氧之间的平衡失调。当前应用的抗心绞痛药物主要是通过减少心肌耗氧量或增加心肌供氧来发挥作用。常用的防治心绞痛药物包括：① 硝酸酯类和亚硝酸酯类，代表药物为硝酸甘油；②β受体阻滞剂，如普萘洛尔等（请参阅第6章）；③钙拮抗剂，如硝苯地平、地尔硫䓬等；④其他抗心绞痛药物，例如双嘧达莫（潘生丁）、曲美他嗪等。
| 中文名称 | 英文名称 | CAS号 | 化学式 | 结构式图片 |
|---|---|---|---|---|
| 马来酸哌克昔林 | perhexiline maleate | 6724-53-4 | C4H4O4*C19H35N |
|
| 马尼地平 | manidipine | 89226-50-6 | C35H38N4O6 |
|
| 非洛地平 | ethyl methyl 1,4-dihydro-2,6-dimethyl-4(2,3-dichlorophenyl)-3,5-pyridinedicarboxylate | 72509-76-3 | C18H19Cl2NO4 |
|
| 薯蓣皂甙 | dioscin | 19057-60-4 | C45H72O16 |
|
| 葛根素 | puerarin | 3681-99-0 | C21H20O9 |
|
| 萘哌地尔 | naftopidil | 57149-07-2 | C24H28N2O3 |
|
| 苯磺酸氨氯地平 | amlodipine besylate | 111470-99-6 | C6H6O3S*C20H25ClN2O5 |
|
| 苄普地尔盐酸盐 | N-benzyl-N-[3-(2-methylpropoxy)-2-(pyrrolidin-1-yl)propyl]aniline hydrochloride--water (1/1) | 74764-40-2 | C24H37ClN2O2 |
|
| 苄普地尔 | bepridil | 64706-54-3 | C24H34N2O |
|
| 美普地尔 | 3-(3,3-diphenylpropylamino)propyl 3,4,5-trimethoxybenzoate | 23891-60-3 | C28H33NO5 |
|
| 米诺地尔 | minoxidil | 38304-91-5 | C9H15N5O |
|
| 磷酸肌酸 | Phosphocreatine | 67-07-2 | C4H10N3O5P |
|
| 碘化N,N,N-三甲基-2-{[2-(戊基桥氧基)丙酰]氧代}乙铵 | Piperazine, 1-[(1-pyrrolidinylcarbonyl)methyl]-4-(3,4,5-trimethoxycinnamoyl)-, maleate | 26328-04-1 | C4H4O4*C22H31N3O5 |
|
| 硝酸异山梨酯 | isosorbide dinitrate | 87-33-2 | C6H8N2O8 |
|
| 硝苯地平 | nifedipine | 193689-82-6 | C17H18N2O6 |
|
| 盐酸萘哌地尔 | Naftopidil dihydrochloride | 57149-08-3 | C24H30Cl2N2O3 |
|
| 盐酸法舒地尔 | fasudil hydrochloride | 105628-07-7 | C14H17N3O2S*ClH |
|
| 盐酸替罗非班 | tirofiban hydrochloride | 142373-60-2 | C22H36N2O5S*ClH |
|
| 盐酸替罗非班 | tirofiban hydrochloride monohydrate | 150915-40-5 | C22H36N2O5S*ClH*H2O |
|
| 盐酸巴尼地平 | Barnidipine hydrochloride | 104757-53-1 | C27H29N3O6*ClH |
|
| 盐酸尼卡地平 | nicardipine hydrochloride | 69441-18-5 | C26H29N3O6*ClH |
|
| 盐酸奥昔非君 | hydron;3-[[(1R,2S)-1-hydroxy-1-phenylpropan-2-yl]amino]-1-(3-methoxyphenyl)propan-1-one;chloride | 16777-42-7 | C19H24ClNO3 |
|
| 盐酸地尔硫卓 | diltiazem hydrochloride | 33286-22-5 | C22H26N2O4S*ClH |
|
| 环维黄杨星 D | Cyclovirobuxine D | 860-79-7 | C26H46N2O |
|
| 法舒地尔 | fasudil | 103745-39-7 | C14H17N3O2S |
|
| 氯达香豆素 | α-(4-chlorophenyl)-2-benzofuranmethanol | 3611-72-1 | C15H11ClO2 |
|
| 氨氯地平 | 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-1,4-dihydropyridine | 88150-42-9 | C20H25ClN2O5 |
|
| 氢普拉明 | droprenilamine | 57653-27-7 | C24H33N |
|
| 桂哌齐特 | cinepazide | 23887-46-9 | C22H31N3O5 |
|
| 替罗非班 | tirofiban | 144494-65-5 | C22H36N2O5S |
|
| 更利芬 | 4-isobutoxy-benzoic acid-(3-diethylamino-1,2-dimethyl-propyl ester) | 299-61-6 | C20H33NO3 |
|
| 曲美他嗪 | 1-(2,3,4-trimethoxybenzyl)piperazine | 5011-34-7 | C14H22N2O3 |
|
| 曲匹地尔 | trapidil | 15421-84-8 | C10H15N5 |
|
| 普尼拉明 | prenylamine | 390-64-7 | C24H27N |
|
| 拉西地平 | Lacidipine | 103890-78-4 | C26H33NO6 |
|
| 巴尼地平 | barnidipine | 104713-75-9 | C27H29N3O6 |
|
| 左旋氨氯地平 | amlodipine | 103129-82-4 | C20H25ClN2O5 |
|
| 川芎嗪 | Tetramethylpyrazine | 1124-11-4 | C8H12N2 |
|
| 尼鲁地平 | niludipine | 22609-73-0 | C25H34N2O8 |
|
| 尼莫地平 | nimodipin | 66085-59-4 | C21H26N2O7 |
|
| 尼群地平 | 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridine-dicarboxylic acid ethyl methyl ester | 39562-70-4 | C18H20N2O6 |
|
| 尼索地平 | nisoldipine | 63675-72-9 | C20H24N2O6 |
|
| 尼可地尔 | N-(2-nitroxyethyl)nicotinamide | 65141-46-0 | C8H9N3O4 |
|
| 尼卡地平 | Nicardipine | 55985-32-5 | C26H29N3O6 |
|
| 奥昔非君 | Oxyfedrine | 15687-41-9 | C19H23NO3 |
|
| 地尔硫卓 | diltiazem | 56209-45-1 | C22H26N2O4S |
|
| 吡那地尔 | pinacidil | 85371-64-8 | C13H19N5*H2O |
|
| 吡那地尔 | pinacidil | 60560-33-0 | C13H19N5 |
|
| 吗多明 | molsidomine | 25717-80-0 | C9H14N4O4 |
|
| 司莫地尔 | Semotiadil | 116476-13-2 | C29H32N2O6S |
|
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