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    首页 分子通 按物质功能分类 原料药 循环系统用药 防治心绞痛药

    防治心绞痛药

    心绞痛是冠状动脉粥样硬化性心脏病（冠心病）的一个重要临床症状。其主要原因是冠状动脉粥样硬化导致管腔狭窄，进而引起心肌血液供应不足，造成心肌供血与需氧之间的平衡失调。当前应用的抗心绞痛药物主要是通过减少心肌耗氧量或增加心肌供氧来发挥作用。常用的防治心绞痛药物包括：① 硝酸酯类和亚硝酸酯类，代表药物为硝酸甘油；②β受体阻滞剂，如普萘洛尔等（请参阅第6章）；③钙拮抗剂，如硝苯地平、地尔硫䓬等；④其他抗心绞痛药物，例如双嘧达莫（潘生丁）、曲美他嗪等。

    中文名称 英文名称 CAS号 化学式 结构式图片
    双嘧达莫 dipyridamole 58-32-2 C24H40N8O4
    双嘧达莫
    加匹可明 bis((pyridin-4-yl)methyl)amine 1539-39-5 C12H13N3
    加匹可明
    利多氟嗪 lidoflazine 3416-26-0 C30H35F2N3O
    利多氟嗪
    凯林 Khellin 82-02-0 C14H12O5
    凯林
    克冠酸 6-(3,4,5-trimethoxybenzamido)hexanoic acid 21434-91-3 C16H23NO6
    克冠酸
    伊拉地平 isradipine 75695-93-1 C19H21N3O5
    伊拉地平
    伊伐布雷定 ivabradine 155974-00-8 C27H36N2O5
    伊伐布雷定
    亚硝酸异戊酯 isopentyl nitrite 110-46-3 C5H11NO2
    亚硝酸异戊酯
    乌拉地尔 urapidil 34661-75-1 C20H29N5O3
    乌拉地尔
    5-单硝酸异山梨酯 isosorbide mononitrate 16051-77-7 C6H9NO6
    5-单硝酸异山梨酯
    4-(1-吡咯烷基)-1-(2,4,6-三甲氧基苯基)-1-丁酮盐酸盐 Buflomedil hydrochloride 35543-24-9 C17H25NO4*ClH
    4-(1-吡咯烷基)-1-(2,4,6-三甲氧基苯基)-1-丁酮盐酸盐
    3-乙基5-甲基2-[(2-氨基乙氧基)甲基]-4-(2-氯苯基)-6-甲基-1,4-二氢-3,5-吡啶二羧酸酯 (R)-amlodipine 103129-81-3 C20H25ClN2O5
    3-乙基5-甲基2-[(2-氨基乙氧基)甲基]-4-(2-氯苯基)-6-甲基-1,4-二氢-3,5-吡啶二羧酸酯
    —— (2RS)-1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-(naphthalene-1-yloxy)propan-2-ol monohydrochloride 57149-08-3 C24H28N2O3*ClH
    (2RS)-1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-(naphthalene-1-yloxy)propan-2-ol monohydrochloride
    —— Cinpropazide 23887-47-0 C21H31N3O5
    Cinpropazide
    —— 8-(beta-D-Glucopyranosyl)-4',7-dihydroxyisoflavone 3681-99-0 C21H20O9
    8-(beta-D-Glucopyranosyl)-4',7-dihydroxyisoflavone
    —— cinepazide maleate 28044-44-2 C4H4O4*C22H31N3O5
    cinepazide maleate
    —— (E)-but-2-enedioic acid;(E)-1-[4-(2-oxo-2-pyrrolidin-1-ylethyl)piperazin-1-yl]-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one 26328-04-1 C26H35N3O9
    (E)-but-2-enedioic acid;(E)-1-[4-(2-oxo-2-pyrrolidin-1-ylethyl)piperazin-1-yl]-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one
    —— erythritol tetranitrate 7297-25-8 C4H6N4O12
    erythritol tetranitrate
    —— Oxyfedrin 10097-61-7 C19H23NO3
    Oxyfedrin
    —— 2H-1,4-Benzothiazin-3(4H)-one, 2-[2-[3-[[2-(1,3-benzodioxol-5-yloxy)ethyl]methylamino]propoxy]-5-methoxyphenyl]-4-methyl-, (2R)-, (2E)-2-butenedioate (1:1) (9CI) 116476-13-2 C29H32N2O6S
    2H-1,4-Benzothiazin-3(4H)-one, 2-[2-[3-[[2-(1,3-benzodioxol-5-yloxy)ethyl]methylamino]propoxy]-5-methoxyphenyl]-4-methyl-, (2R)-, (2E)-2-butenedioate (1:1) (9CI)
    —— 6-{3-[4-(2-Methoxy-5-methyl-phenyl)-piperazin-1-yl]-propylamino}-1,3-dimethyl-1H-pyrimidine-2,4-dione 34661-75-1 C21H31N5O3
    6-{3-[4-(2-Methoxy-5-methyl-phenyl)-piperazin-1-yl]-propylamino}-1,3-dimethyl-1H-pyrimidine-2,4-dione
    —— trimetazidine dihydrochloride 13171-25-0 C14H22N2O3*2ClH
    trimetazidine dihydrochloride
    —— 1,4:3,6-Dianhydro-D-iditol-2,5-dinitrat 87-33-2 C6H8N2O8
    1,4:3,6-Dianhydro-D-iditol-2,5-dinitrat
    —— methyl (4S)-1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5-pyridinedicarboxylate-2-(4-diphenylmethyl-1-piperazinyl)ethyl ester hydrochloride 89226-75-5 C35H38N4O6*2ClH
    methyl (4S)-1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5-pyridinedicarboxylate-2-(4-diphenylmethyl-1-piperazinyl)ethyl ester hydrochloride
    —— Manidipine dihydrochloride 89226-75-5 C35H38N4O6*2ClH
    Manidipine dihydrochloride
    —— isosorbide-5-mononitrate 16051-77-7 C6H9NO6
    isosorbide-5-mononitrate
    —— [(3S,6R)-3-hydroxy-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-6-yl] nitrate 16051-77-7 C6H9NO6
    [(3S,6R)-3-hydroxy-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-6-yl] nitrate
    —— 1,4;3,6-Dianhydro-D-glucitol-2-nitrat 16051-77-7 C6H9NO6
    1,4;3,6-Dianhydro-D-glucitol-2-nitrat
    —— benidipine 105979-17-7 C28H31N3O6
    benidipine
    —— pranidipine 99522-79-9 C25H24N2O6
    pranidipine
    —— 3-O-{α-L-rhamnopyranosyl-(1→4)-[α-L-rhamnopyranosyl-(1→2)]-β-D-glucopyranosyl}-25(S)-spirost-5-en-3β-ol 19057-60-4 C45H72O16
    3-O-{α-L-rhamnopyranosyl-(1→4)-[α-L-rhamnopyranosyl-(1→2)]-β-D-glucopyranosyl}-25(S)-spirost-5-en-3β-ol
    —— Dioscin 19057-60-4 C45H72O16
    Dioscin
    —— Puerarin 3681-99-0 C21H20O9
    Puerarin