3-(1H,1H,7H-十二氟庚氧基)-1,2-环氧丙烯酸 | 799-34-8

• 物质功能分类: 有机原料 - 有机氟化合物
• 分子结构分类: 有机化合物 - 有机杂环化合物 - 环氧化物
• 中文名称: 3-(1H,1H,7H-十二氟庚氧基)-1,2-环氧丙烯酸
• 中文别名: 3-氯-5-氟苯甲醇；3-氯-5-氟苄醇；3-(1H,1H,7H-十二氟庚氧基)-1,2-环氧丙烷
• 英文名称: (2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoroheptyloxymethyl)oxirane
• 英文别名: 7,7,6,6,5,5,4,4,3,3,2,2-Dodecafluoroheptyloxymethyl oxirane；1H,1H,7H-dodecafluoroheptyl 2,3-epoxypropyl ether；glycidyl 2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoroheptyl ether；2-(2,2,3,3,4,4,5,5,6,6,7,7-Dodecafluoroheptoxymethyl)oxirane
• CAS: 799-34-8
• 化学式: C₁₀H₈F₁₂O₂
• 分子量: 388.153
• InChiKey: BUSYHRRDAMGPJN-UHFFFAOYSA-N

物化性质

• 沸点：
  97-98 °C4 mm Hg(lit.)
• 密度：
  1.614 g/mL at 25 °C(lit.)
• 闪点：
  >230 °F

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  24
• 可旋转键数：
  9
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  21.8
• 氢给体数：
  0
• 氢受体数：
  14

安全信息

• 危险等级：
  IRRITANT
• 危险品标志：
  Xi
• 安全说明：
  S26,S36
• 危险类别码：
  R36/37/38
• WGK Germany：
  3

反应信息

• 作为反应物：
  描述：

  3-(1H,1H,7H-十二氟庚氧基)-1,2-环氧丙烯酸 在 phosphocholine sodium salt 、 三乙胺 作用下， 以 甲醇 、 氯仿 为溶剂， 反应 28.0h， 生成 [2-acetyloxy-3-(2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoroheptoxy)propyl] 2-(trimethylazaniumyl)ethyl phosphate
  参考文献：
  名称：

  Synthesis and antihypertensive activity of some 1-o-alkylglycero-3-phosphocholine derivatives

  摘要：

  DOI：

  10.1007/bf02333883
• 作为产物：
  描述：

  十二氟庚醇 、 环氧氯丙烷 在 sodium hydroxide 作用下， 反应 5.0h， 以43%的产率得到3-(1H,1H,7H-十二氟庚氧基)-1,2-环氧丙烯酸
  参考文献：
  名称：

  An approach to fluorinated surface coatings via photoinitiated cationic cross-linking of mixed epoxy and fluoroepoxy systems

  摘要：

  The synthesis and characterisation of four polyfluorinated monoepoxides is described. These fluoroepoxy monomers were cationically polymerised either neat or as mixtures with diglycidylether of bisphenol-A using the initiator system (CH3CH2)(3)Al/H2O (2/1) or the photoinitiator Ph2I+, PF6-. Contact angle measurements indicated that, in favourable cases, the fluorinated epoxide monomer surface segregated at low loadings to give significant lowering of the surface free energy of photocured films of diglycidylether of bisphenol-A. (C) 2000 Elsevier Science S.A. All rights reserved.

  DOI：

  10.1016/s0022-1139(99)00288-2

文献信息

• [EN] PROCESS FOR PRODUCING DIHYDROISOQUINOLINE ZWITTERIONS<br/>[FR] PROCEDE DE PRODUCTION DE ZWITTERIONS DE DIHYDROISOQUINOLINE
  申请人：PROCTER & GAMBLE

  公开号：WO2005047264A1

  公开（公告）日：2005-05-26

  This invention relates to a preparation of zwitterionic sulfates of substituted or unsubstituted 3, 4-dihydroisoquinoline.

  这项发明涉及制备取代或未取代3,4-二氢异喹啉的带电离子硫酸盐。
• A comparative study of the reactions of fluorinated oxi- and thiiranes with acyl chlorides
  作者：S. A. Nalet´ko、M. G. Pervova、M. I. Kodess、M. S. Toporova、T. I. Gorbunova、A. Ya. Zapevalov、V. I. Saloutin

  DOI：10.1007/s11172-017-1848-y

  日期：2017.6

  The CoCl2-catalyzed reactions of fluorinated 1,2-oxi- and thiiranes with acyl chlorides were studied. It was found that a regioselective heterocycle opening reaction resulted in two isomers having normal and abnormal structure in a ratio predetermined by the substituents in both the starting heterocycles and acyl chlorides.

  研究了 CoCl2 催化的氟化 1,2-氧杂和硫杂丙烷与酰氯的反应。发现区域选择性杂环开环反应产生具有正常和异常结构的两种异构体，其比例由起始杂环和酰氯中的取代基预先确定。
• SYNTHESIS OF CYCLIC TRITHIOCARBONATES FROM EPOXIDES
  申请人：Parker Kenton Dane

  公开号：US20060004210A1

  公开（公告）日：2006-01-05

  This invention provides a low cost technique for synthesizing cyclic trithiocarbonates by a simple one step process from epoxides that can be conducted under atmospheric pressure. This synthesis can be depicted as follows: wherein R represents a moiety selected from the group consisting of alkyl groups and aryl groups, wherein R′ represents a moiety selected from the group consisting of alkyl groups, aryl groups, and hydrogen atoms, and wherein R″ represents a moiety selected from the group consisting of alkyl groups, aryl groups, and hydrogen atoms, wherein the R moiety and the R′ moiety can be bonded together to form a cyclic structure, with the proviso that R″ represents a hydrogen atom if R′ represents an alkyl group or an aryl group. In this process carbon disulfide and a thiocyanate salt, such as potassium thiocyanate, are reacted with the epoxide in an ionic liquid, such as 1-butyl-3-methylimidazolium hexafluorophosphate ([Bmim] PF 6 ) in the presence of water to produce the cyclic trithiocarbonate.

  这项发明提供了一种低成本的技术，通过简单的一步法从环氧化物合成环状三硫代碳酸酯，可以在大气压下进行。该合成可表示为：其中R代表从烷基和芳基组成的基团，R'代表从烷基、芳基和氢原子组成的基团，R''代表从烷基、芳基和氢原子组成的基团，其中R基团和R'基团可以结合形成环状结构，但前提是如果R'代表烷基或芳基，则R''代表氢原子。在该过程中，二硫化碳和硫氰酸盐（如硫氰酸钾）与环氧化物在离子液体（如1-丁基-3-甲基咪唑六氟磷酸盐[Bmim] PF6）中在水的存在下反应，生成环状三硫代碳酸酯。
• Process of producing an organic catalyst
  申请人：Hiler Douglas George

  公开号：US20050113246A1

  公开（公告）日：2005-05-26

  This invention relates to a process of producing organic catalysts that may comprise iminium or oxaziridinium moieties, cleaning compositions comprising such catalysts; and methods of using such catalysts and cleaning products containing such catalysts.

  本发明涉及一种生产含有亚胺或氧杂环丙烷基团的有机催化剂的方法，以及包含这种催化剂的清洁组合物；以及使用这种催化剂和含有这种催化剂的清洁产品的方法。
• Catalyst component for the polymerisation of olefins and process for preparing olefin polymers using same
  申请人：NIPPON OIL COMPANY, LIMITED

  公开号：EP0587440A2

  公开（公告）日：1994-03-16

  A catalyst component for use in the polymerization or copolymerization of olefin(s) is obtained by contacting the following components (1) to (4) with one another: (1) a compound of the general formula Me¹R¹p(OR²)qX¹4-p-q where R¹ is a hydrocarbon radical having 1 to 24 carbon atoms, X¹ is a halogen atom, Me¹ is Zr, Ti or Hf, and n is 0 ≦ n ≦ 4; (2) a compound of the general formula Me²R³m(OR⁴)nX²z-m-n where R² is a hydrocarbon radical having 1 to 24 carbon atoms, X² is a halogen atom, Me² is an element from Groups I to III in the Periodic Table, z is the valence of Me² and m is 0 ≦ m ≦ z; (3) an organocyclic compound having two or more conjugated double bonds; and (4) a modified organoaluminum compound containing Al-O-Al bond and with at least one branched-chain alkyl group being attached to aluminum atom.

  将下列组分（1）至（4）相互接触，可得到用于烯烃聚合或共聚的催化剂组分： (1) 通式为 Me¹R¹p(OR²)qX¹4-p-q的化合物 其中，R¹为具有 1 至 24 个碳原子的烃基；X¹为卤素原子；Me¹为 Zr、Ti 或 Hf；n 为 0 ≦ n ≦ 4； (2) 通式为 Me²R³m(OR⁴)nX²z-m-n的化合物，其中 R²为具有 1 至 24 个碳原子的烃基；X²为卤素原子；Me²为元素周期表中第 I 至 III 族的元素；z 为 Me²的化合价；m 为 0 ≦ m ≦ z； (3) 具有兩個或以上共轭双键的有机环化合物；及 (4) 含 Al-O-Al 键且至少有一个支链烷基与铝原子相连的改性有机铝化合物。