(4-benzoyl-3-hydroxyphenoxy)acetic acid | 3739-72-8

• 物质功能分类: 有机原料 - 羧酸类化合物及衍生物
• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (4-benzoyl-3-hydroxyphenoxy)acetic acid
• 英文别名: 2-(4-Benzoyl-3-hydroxyphenoxy)acetic acid
• CAS: 3739-72-8
• 化学式: C₁₅H₁₂O₅
• 分子量: 272.257
• InChiKey: IFKOZECKOCUMKI-UHFFFAOYSA-N

物化性质

• 熔点：
  160-161 °C(Solv: acetic acid (64-19-7))
• 沸点：
  474.6±35.0 °C(Predicted)
• 密度：
  1.353±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  20
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  83.8
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  (4-benzoyl-3-hydroxyphenoxy)acetic acid 在 氯化亚砜 作用下， 生成 3-Hydroxy-4-benzoyl-phenoxyessigsaeurchlorid
  参考文献：
  名称：

  亲核取代过程中芳基卤乙酸酯的重排

  摘要：

  芳基卤代乙酸酯与醇或酚在含碳酸钾的丙酮中的反应导致衍生物，其中更碱性的亲核试剂与羰基连接。如果需要产生该衍生物，则发生重排。

  DOI：

  10.1039/j39690000037
• 作为产物：
  描述：

  2,4-二羟二苯甲酮 在 18-冠醚-6 、 potassium carbonate 、 三氟乙酸 、 potassium iodide 作用下， 以 二氯甲烷 、 丙酮 为溶剂， 反应 3.0h， 生成 (4-benzoyl-3-hydroxyphenoxy)acetic acid
  参考文献：
  名称：

  [EN] A SUNSCREEN FORMULATION
  [FR] FORMULATION D'ÉCRAN SOLAIRE

  摘要：

  本文披露了新型防晒剂的合成方法，以及使用这些防晒剂在防晒配方中旨在减少防晒剂对皮肤的渗透，并且使用现有的防晒剂配方技术旨在减少防晒剂对皮肤的渗透，从而提高防晒产品的生物安全性。

  公开号：

  WO2020082296A1

文献信息

• Agrochemical Composition Comprising Pesticide and UV Absorber
  申请人：Misske Andrea

  公开号：US20110237665A1

  公开（公告）日：2011-09-29

  The present invention relates to an agrochemical composition comprising pesticide and UV absorber, and the abovementioned UV absorbers. The invention furthermore relates to the use of the UV absorbers in agrochemical compositions. It moreover relates to a method of controlling phytopathogenic fungi and/or undesirable plant growth and/or undesirable insect or mite infestation and/or of regulating plant growth.

  本发明涉及一种包括杀虫剂和紫外线吸收剂的农药组合物，以及上述紫外线吸收剂。此外，该发明还涉及在农药组合物中使用紫外线吸收剂。此外，它还涉及一种控制植物病原真菌和/或不良植物生长和/或不良昆虫或螨虫侵袭和/或调节植物生长的方法。
• A UV-Blocking Polymer Shell Prevents One-Photon Photoreactions while Allowing Multi-Photon Processes in Encapsulated Upconverting Nanoparticles
  作者：Tuoqi Wu、Madeleine Barker、Khaled M. Arafeh、John-Christopher Boyer、Carl-Johan Carling、Neil R. Branda

  DOI：10.1002/anie.201305253

  日期：2013.10.11

  Sun block for nanoparticles: Unintentional photorelease triggered by UV light is a problem in photodynamic therapy. Encapsulating upconverting nanoparticles containing photoswitches in a UV‐blocking amphiphilic polymer shuts down the one‐photon process and only allows two‐photon‐driven photochemistry. Thus, UV light is blocked while NIR light can reach the nanoparticle core and trigger photorelease

  纳米粒子的防晒霜：由紫外线引发的意外光释放是光动力疗法中的一个问题。将包含光开关的上转换纳米粒子封装在阻隔紫外线的两亲性聚合物中会关闭单光子过程，并且仅允许双光子驱动的光化学过程。因此，紫外线被阻挡，而近红外光可以到达纳米颗粒的核心并触发光释放。
• Latent mercaptans as multi-functional additives for halogen-containing polymer compositions
  申请人：——

  公开号：US20030216493A1

  公开（公告）日：2003-11-20

  Halogen-containing polymer compositions comprising a latent mercaptan-containing heat stabilizer composition substantially free from the offensive odor typically associated with mercaptans are protected during processing by the degradation products of the latent (i.e., blocked) mercaptan which include a free mercaptan. Other products of the degradation are believed to include carbocations of the blocking moiety which are stabilized by a molecular structure in which the electron deficiency is shared by several groups. The latent mercaptan may be the sole heat stabilizer additive but the free mercaptan released during processing may also synergize the activity of metal-based heat stabilizers such as metal salts and organometallic stabilizers such as organotin carboxylates and mercaptides in the polymer composition. The odor of primary mercaptan-containing heat stabilizers in halogenated polymer compositions is masked by a small amount of a latent mercaptan. The latent mercaptans also serve as intermediates in the preparation of anti-oxidants, anti-microbial agents, photostabilizers, and primary heat stabilizers. Highly effective heat stabilizers are prepared by the condensation of formaldehyde and a para-phenol and further condensation of the crude product with a mercapto-containing compound.

  含卤素聚合物组合物包括一种潜在的巯基含量热稳定剂组合物，该组合物基本上不含有通常与巯基相关联的刺激性气味，在加工过程中通过潜在（即被阻断的）巯基的降解产物（包括自由巯基）来保护。降解的其他产物被认为包括阻断基的碳正离子，其通过电子亏损由几个基团共享的分子结构稳定。潜在巯基可以是唯一的热稳定剂添加剂，但在加工过程中释放的自由巯基也可以协同作用于金属基热稳定剂，如金属盐和有机金属稳定剂，如有机锡羧酸盐和巯基化合物在聚合物组合物中的活性。通过少量潜在巯基掩盖含有主要巯基热稳定剂的卤化聚合物组合物的气味。潜在巯基还可用作抗氧化剂、抗微生物剂、光稳定剂和主要热稳定剂的制备中间体。通过甲醛和对苯酚的缩合，并将粗产品与含巯基的化合物进一步缩合，可以制备高效的热稳定剂。
• LATENT MERCAPTANS AS MULTI-FUNCTIONAL ADDITIVES FOR HALOGEN-CONTAINING POLYMER COMPOSITIONS
  申请人：——

  公开号：US20020068780A1

  公开（公告）日：2002-06-06

  Halogen-containing polymer compositions comprising a latent mercaptan-containing heat stabilizer composition substantially free from the offensive odor typically associated with mercaptans are protected during processing by the degradation products of the latent (i.e., blocked) mercaptan which include a free mercaptan. Other products of the degradation are believed to include carbocations of the blocking moiety which are stabilized by a molecular structure in which the electron deficiency is shared by several groups. The latent mercaptan may be the sole heat stabilizer additive but the free mercaptan released during processing may also synergize the activity of metal-based heat stabilizers such as metal salts and organometallic stabilizers such as organotin carboxylates and mercaptides in the polymer composition. The odor of primary mercaptan-containing heat stabilizers in halogenated polymer compositions is masked by a small amount of a latent mercaptan. The latent mercaptans also serve as intermediates in the preparation of anti-oxidants, anti-microbial agents, photostabilizers, and primary heat stabilizers. Highly effective heat stabilizers are prepared by the condensation of formaldehyde and a para-phenol and further condensation of the crude product with a mercapto-containing compound.

  含卤素的聚合物组合物包括一种潜在的巯基含量热稳定剂组合物，该组合物基本上不含通常与巯基相关的刺激性气味，通过潜在（即阻塞）巯基的降解产物，包括自由巯基，来保护加工过程中的聚合物组合物。降解的其他产物被认为包括阻塞基的碳正离子，其由多个基团共享电子亏损的分子结构稳定。潜在巯基可以是唯一的热稳定剂添加剂，但在加工过程中释放的自由巯基也可以协同金属基热稳定剂（如金属盐）和有机金属稳定剂（如有机锡羧酸盐和巯基化合物）的活性。在卤化聚合物组合物中，主要巯基含量热稳定剂的气味被少量潜在巯基掩盖。潜在巯基还可用作抗氧化剂、抗微生物剂、光稳定剂和主要热稳定剂的制备中间体。通过甲醛和对苯酚的缩聚，并将粗品与含巯基化合物进一步缩聚，制备出高效的热稳定剂。
• Thioether substituted hydroxybenzophenones and stabilized compositions
  申请人：Ciba Specialty Chemicals Corporation

  公开号：US06576797B1

  公开（公告）日：2003-06-10

  2-Hydroxybenzophenone derivatives substituted in the 4′-position by a thioether moiety exhibit enhanced absorption in the UV at longer wavelength. Compositions comprising organic material subject to actinic degradation are beneficially stabilized with such derivatives.

  在4'-位置被硫醚基取代的2-羟基苯甲酮衍生物在紫外线较长波长处表现出增强的吸收性。 包含易受光降解的有机材料的组合物通过这种衍生物的稳定化而受益。