biohanin A-7-glucoside | 20594-05-2

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 异黄酮类化合物
• 英文名称: biohanin A-7-glucoside
• 英文别名: 7-O-(β-D-glucopyranosyl)-3-phenyl-4H-chromen-4-one；7-β-D-glucopyranosyloxy-3-phenyl-chromen-4-one；7-β-D-Glucopyranosyloxy-3-phenyl-chromen-4-on；Isoflavone 7-O-beta-D-glucoside；3-phenyl-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one
• CAS: 20594-05-2
• 化学式: C₂₁H₂₀O₈
• 分子量: 400.385
• InChiKey: CHVBPFQVSIWBOU-QNDFHXLGSA-N

物化性质

• 熔点：
  170 °C
• 沸点：
  676.8±55.0 °C(Predicted)
• 密度：
  1.503±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  29
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  126
• 氢给体数：
  4
• 氢受体数：
  8

反应信息

• 作为产物：
  描述：

  7-(tetra-o-acetyl-β-D-glucopyranosyloxy)isoflavone 在 甲醇 、 sodium methylate 作用下， 反应 24.0h， 以100%的产率得到biohanin A-7-glucoside
  参考文献：
  名称：

  Highly efficient glucosylation of flavonoids

  摘要：

  A highly efficient procedure for glucosylation of flavonoids by acetobromoglucose is described. Glucosylation is carried out in a two-phase system CHCl3/H2O over 96 h using tetrabutylammonium bromide as phase-transfer catalyst. A purification procedure can be performed without column chromatography, and the yields of the glucosylated flavonoids are mostly quantitative. Acetylated glucosides were deprotected with sodium methanolate to afford the desired glucosides of flavonoids.

  DOI：

  10.1007/s00706-009-0207-6

文献信息

• METHOD FOR PREPARATION OF DIESTER DERIVATIVES OF MALONIC ACID
  申请人：Lygos, Inc.

  公开号：US20200399666A1

  公开（公告）日：2020-12-24

  Methods for the preparation of bio-based malonic acid and diester derivatives of malonic acid are provided. The disclosed methods produce diester derivatives of malonic acid with fewer impurities, which is useful for many industrial processes. The diester derivatives of malonic acid can be purified from existing sources of malonic acid, or from malonic acid made from a renewable carbon source.

  本文提供了制备基于生物的丙二酸和丙二酸二酯衍生物的方法。公开的方法可以生产较少杂质的丙二酸二酯衍生物，这对许多工业过程有用。丙二酸二酯衍生物可以从现有的丙二酸来源或从可再生碳源制备的丙二酸中纯化。
• Zemplen et al., Chemische Berichte, 1944, vol. 77/79, p. 452,455
  作者：Zemplen et al.

  DOI：——

  日期：——