7,8-二氧杂双环[3.2.1]辛烷-6-酮 | 5257-20-5

• 物质功能分类: 有机原料 - 酮类化合物
• 分子结构分类: 有机化合物 - 有机杂环化合物 - 内酯类
• 中文名称: 7,8-二氧杂双环[3.2.1]辛烷-6-酮
• 英文名称: 7-Oxo-6,8-dioxabicyclo<3.2.1>octane
• 英文别名: 6,8-dioxa-bicyclo[3.2.1]octan-7-one；6,8-Dioxa-bicyclo[3.2.1]octan-7-on；6-hydroxytetrahydropyran-2-carboxylic acid lactone；opt.-inakt. 6-Hydroxy-tetrahydropyran-carbonsaeure-(2)-lacton；6-Hydroxytetrahydropyran-2-carbonsaeurelacton；6,8-Dioxabicyclo[3.2.1]octan-7-one
• CAS: 5257-20-5
• 化学式: C₆H₈O₃
• 分子量: 128.128
• InChiKey: FDTQYEHORIQWRC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  9
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  35.5
• 氢给体数：
  0
• 氢受体数：
  3

安全信息

• 海关编码：
  2932999099

反应信息

• 作为反应物：
  描述：

  7,8-二氧杂双环[3.2.1]辛烷-6-酮 在 氨 、 水 、 镍 作用下， 80.0~118.0 ℃ 、11.2 kPa 条件下， 生成 6-amino-2-hydroxy-hexanoic acid amide
  参考文献：
  名称：

  Reactions of Acrolein and Related Compounds. IV. Preparation of a New Lactone, 7-Oxo-6,8-dioxabicyclo [3.2.1] octane from Acrolein Dimer, and Its Conversion to Lysine

  摘要：

  DOI：

  10.1021/ja01155a079
• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 sodium hydroxide 作用下， 生成 7,8-二氧杂双环[3.2.1]辛烷-6-酮
  参考文献：
  名称：

  Reactions of Acrolein and Related Compounds. IV. Preparation of a New Lactone, 7-Oxo-6,8-dioxabicyclo [3.2.1] octane from Acrolein Dimer, and Its Conversion to Lysine

  摘要：

  DOI：

  10.1021/ja01155a079

文献信息

• Poly(glycolic acid)/poly(oxyethylene)triblock copolymers and method of manufacturing the same
  申请人：AMERICAN CYANAMID COMPANY

  公开号：EP0108933A1

  公开（公告）日：1984-05-23

  Poly(glycolic acid)poly(oxyethylene) ABA triblock copolymers having the following formula: wherein x ist about 37.5 to 47.5 and y is about 5 to 25, weight percent. The copolymers are useful for manufacturing fibers possessing a sufficiently low modulus of elasticity to permit their use as absorbable sutures having the requisite flexibility for use in monofilament form. A process of preparation involves purifying the hydroxyl-ended poly(oxyalkylene) and allowing it to react with glycolide to produce an ABA triblock copolymer of extrusion grade in which A represents a polyglycolic acid block and B represents a poly(oxyalkylene) block.

  具有下式的聚羟基乙酸聚氧乙烯 ABA 三嵌段共聚物： 其中 x 约为 37.5 至 47.5，y 约为 5 至 25，重量百分比。这种共聚物可用于制造具有足够低弹性模量的纤维，使其可用作可吸收缝合线，并具有以单丝形式使用所需的柔韧性。制备工艺包括纯化羟基端聚（氧烷基），使其与乙二醛反应生成挤出级 ABA 三嵌段共聚物，其中 A 代表聚羟基乙酸嵌段，B 代表聚（氧烷基）嵌段。
• Process of preparation of a polymer in the presence of a phosphazenium salt
  申请人：Mitsui Chemicals, Inc.

  公开号：EP0879838A2

  公开（公告）日：1998-11-25

  A process of preparing a polymer comprises conducting ring-opening polymerization of a 4- to 10-membered ring-opening polymerizable cyclic monomer in the presence of a phosphazenium salt of an active hydrogen compound represented by the chemical formula (1) : wherein n is an integer of 1 to 8 and indicates the number of phosphazenium cations, Zn- is an anion of a n-valent active hydrogen compound derived by releasing n protons from an active hydrogen compound having a maximum of 8 active hydrogen atoms, a, b, c and d are individually a positive integer or 0 and are not all 0 at the same time, R's are the same or different hydrocarbons having 1 to 10 carbon atoms, and two R's located on each common nitrogen atom may be coupled together to form a ring structure ; or in the presence of the phosphazenium salt of the active hydrogen compound and the active hydrogen compound. The process can produce a polymer by ring-opening polymerization of a 4- to 10-membered ring-opening polymerizable cyclic monomer in the presence of an initiator which causes no specific problems in terms of preparation and handling, contains no metallic ingredients and has no residual odor.

  制备聚合物的工艺包括在化学式(1)代表的活性氢化合物的磷硒盐存在下，对 4 至 10 元环可开环聚合的环状单体进行开环聚合： 其中 n 是 1 至 8 的整数，表示磷硒阳离子的数目；Zn- 是 n 价活性氢化合物的阴离子，通过从最多具有 8 个活性氢原子的活性氢化合物中释放 n 个质子而得到；a、b、c 和 d 各为正整数或 0，且不同时均为 0；R 是具有 1 至 10 个碳原子的相同或不同的碳氢化合物；位于每个公共氮原子上的两个 R 可耦合在一起以形成环结构；或在活性氢化合物的磷硒盐和活性氢化合物的存在下。 该工艺可在引发剂存在下，通过 4 至 10 元环可开环聚合环状单体的开环聚合反应生产聚合物，该聚合物在制备和处理方面不会产生特殊问题，不含金属成分，也没有残留气味。
• Notes: 6-Alkoxytetrahydropyran-2-carboxylates
  作者：J Brezinski、D Kubler、A Montagna

  DOI：10.1021/jo01093a618

  日期：1959.11
• OKADA, MASAHIKO;TAJIMA, ICHIRO;SUMITOMO, HIROSHI, CONTEMP. TOP. POLYM. SCI. PROC. US-JAP. POLYM. SYMP. 10TH BIENN. SYMP., P+
  作者：OKADA, MASAHIKO、TAJIMA, ICHIRO、SUMITOMO, HIROSHI

  DOI：——

  日期：——
• OKADA, MASAHIKO;SUMITOMO, HIROSHI;ATSUMI, MIHARU, J. AMER. CHEM. SOC., 1984, 106, N 7, 2101-2104
  作者：OKADA, MASAHIKO、SUMITOMO, HIROSHI、ATSUMI, MIHARU

  DOI：——

  日期：——

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