Honyucitrin;5,7-二羟基-2-[4-羟基-3,5-双(3-甲基-2-丁烯-1-基)苯基]-4H-1-苯并吡喃-4-酮 | 114542-44-8

• 物质功能分类: 天然产物 - 黄酮类化合物
• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 中文名称: Honyucitrin;5,7-二羟基-2-[4-羟基-3,5-双(3-甲基-2-丁烯-1-基)苯基]-4H-1-苯并吡喃-4-酮
• 英文名称: Honyucitrin
• 英文别名: 5,7-dihydroxy-2-[4-hydroxy-3,5-bis(3-methylbut-2-enyl)phenyl]chromen-4-one
• CAS: 114542-44-8
• 化学式: C₂₅H₂₆O₅
• 分子量: 406.5
• InChiKey: DOFKPAVSYGZVQD-UHFFFAOYSA-N

物化性质

• 沸点：
  615.7±55.0 °C(Predicted)
• 密度：
  1.246±0.06 g/cm3(Predicted)
• 溶解度：
  溶于氯仿、二氯甲烷、乙酸乙酯、DMSO、丙酮等。
• 物理描述：
  Solid
• 熔点：
  199.5-201°C

计算性质

• 辛醇/水分配系数(LogP)：
  5.6
• 重原子数：
  30
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.24
• 拓扑面积：
  87
• 氢给体数：
  3
• 氢受体数：
  5

文献信息

• COMPOSITIONS OF AZADIRACHTA INDICA AND METHODS OF TREATING CANCER
  申请人：Board of Regents, The University of Texas System

  公开号：EP3843764A1

  公开（公告）日：2021-07-07
• Compositions of Azadirachta Indica and Methods of Treating Cancer
  申请人：Board of Regents of the University of Texas System

  公开号：US20200253916A1

  公开（公告）日：2020-08-13

  The disclosure relates to compositions and methods of treating cancer in a subject. The method comprises administering to a patient in need of treatment an effective amount of supercritical CO 2 neem extract.
• [EN] COMPOSITIONS OF AZADIRACHTA INDICA AND METHODS OF TREATING CANCER<br/>[FR] COMPOSITIONS D'AZADIRACHTA INDICA ET MÉTHODES DE TRAITEMENT DU CANCER
  申请人：UNIV TEXAS

  公开号：WO2020047405A1

  公开（公告）日：2020-03-05

  The disclosure relates to compositions and methods of treating cancer in a subject. The method comprises administering to a patient in need of treatment an effective amount of supercritical CO2 neem extract. The disclosure also relates to a process for preparing a CO2 extract of Azadirachta indica and herbal compositions thereof for the treatment of oral and colon cancers. The methods comprise a process for preparing a standardized SCO2 extract of Azadirachta indica leaves and herbal compositions of the same for oral use.