申请人:Coleman Paul J.
公开号:US20080207693A1
公开(公告)日:2008-08-28
The present invention relates to dihydropyrazole compounds that are useful for treating cellular proliferative diseases, for treating disorders associated with KSP kinesin activity, and for inhibiting KSP kinesin. The invention also related to compositions which comprise these compounds, and methods of using them to treat cancer in mammals.
本发明涉及二氢吡唑化合物,对于治疗细胞增殖性疾病,治疗与KSP动力蛋白活性相关的疾病,以及抑制KSP动力蛋白具有用处。该发明还涉及包含这些化合物的组合物,以及使用它们治疗哺乳动物癌症的方法。