| 1303612-77-2

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• CAS: 1303612-77-2
• 化学式: C₁₁H₁₃NO₃
• 分子量: 207.229
• InChiKey: JZJJPRPXIYTSAL-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  三甲基氯硅烷 、 在 1-Benzenesulfonyl-2-phenyl-aziridine 、 (S)-N-(2-hydroxyphenyl)-2-(fluoro-2-hydroxybenzoylamino)-3-methylbutanamide 、 praseodymium(III) isopropoxide 、 咪唑 作用下， 以 四氢呋喃 、 二氯甲烷 为溶剂， 反应 25.0h， 生成 、
  参考文献：
  名称：

  Catalytic asymmetric hydroxylation of α-alkoxycarbonyl amides with a Pr(OiPr)3/amide-based ligand catalyst

  摘要：

  A catalytic asymmetric hydroxylation of N-nonsubstituted alpha-alkoxycarbonyl amides is described. A new effective catalyst comprising Pr((OPr)-Pr-i)(3) and a fluoro-substituted amide-based ligand was identified using oxaziridine as the oxidizing reagent. The catalyst components were in dynamic equilibrium in the reaction mixture, which assembled to form the associated transition state through metal coordination and hydrogen bonding. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2010.11.064