D-甘露糖醛酸单糖 | 921-56-2

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: D-甘露糖醛酸单糖
• 英文名称: D-Mannuronic acid, sodium salt (1:1)
• CAS: 921-56-2
• 化学式: C6H10NaO7
• 分子量: 217.13
• InChiKey: QKHMTHNLNZGTSP-MHFWOIHZSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.67
• 重原子数：
  14
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  135
• 氢给体数：
  5
• 氢受体数：
  7

文献信息

• CONTROLLED RELEASE OF TISSUE CULTURE SUPPLEMENTS
  申请人：——

  公开号：US20020081729A1

  公开（公告）日：2002-06-27

  The materials and methods are particularly useful in media for cell culturing but have other applications as well, such as in tissue engineering. The materials comprise at least one growth factor or other cell growth facilitating substance contained within a polymeric structure which can incorporate the substance and allow controlled release of the substance. Alginate materials are particularly useful as the polymeric structure. Another feature described herein is the above-described materials provided in a lyophilized (freeze-dried) form which greatly enhances their storage life.

  这些材料和方法尤其适用于细胞培养的培养基，但也有其他应用，如组织工程。这些材料包括至少一种生长因子或其他促进细胞生长的物质，这些物质包含在一种聚合物结构中，这种聚合物结构可以吸附这种物质，并控制这种物质的释放。藻酸盐材料作为聚合物结构尤其有用。本文所述材料的另一个特点是以冻干形式提供，这大大提高了材料的储存寿命。
• A METHOD OF MAKING BIOCOMPATIBLE CAPSULES CONTAINING CELLS
  申请人：UNIVERSITY OF LEICESTER

  公开号：EP0599942A1

  公开（公告）日：1994-06-08
• US5529913A
  申请人：——

  公开号：US5529913A

  公开（公告）日：1996-06-25
• [EN] A METHOD OF MAKING BIOCOMPATIBLE CAPSULES CONTAINING CELLS
  申请人：UNIVERSITY OF LEICESTER

  公开号：WO1993003710A1

  公开（公告）日：1993-03-04

  (EN) There is disclosed a method of making biocompatible capsules containing cells comprising the steps of suspending cells in an aqueous medium containing a pre-dialysed water soluble gum which has plural anionic moieties but is substantially protein free, forming the suspension into droplets containing the cells, subjecting the droplets to a solution of mutlivalent physiologically compatible cations to gel the droplets, encapsulating said cells, subjecting said gelled droplets to a polymer containing cationic groups which cross-link with said anionic groups to form a semi-permeable membrane and coating said semi-permeable membrane with a layer of said pre-dialysed water soluble gum.(FR) Un procédé de production de capsules biocompatibles contenant des cellules consiste d'abord à mettre des cellules en suspension dans un milieu aqueux qui contient une gomme hydrosoluble pré-dialysée. Cette gomme comporte diverses fractions anioniques mais pratiquement pas de protéines. On obtient ensuite une suspension de gouttelettes contenant des cellules soumises à une solution de cations multivalents physiologiquement compatibles, les gouttelettes sont encapsulées dans un gel puis exposées à un polymère contenant des groupes cationiques, lesquels, en étabilisant une réticulation avec les groupes anioniques forment une membrane semi-perméable. Cette dernière est ensuite recouverte d'une couche de gomme hydrosoluble pré-dialysée.