6-溴-2-萘基-Β-D-吡喃葡糖苷 | 15548-61-5

• 物质功能分类: 生物化工 - 糖类化合物 - 单糖
• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 6-溴-2-萘基-Β-D-吡喃葡糖苷
• 中文别名: 6-溴-2-萘基β-D-吡喃葡萄糖苷；6-溴-2-萘基-β-D-吡喃葡糖苷
• 英文名称: 6-bromo-2-naphthyl-β-D-glucopyranoside
• 英文别名: 6-Bromo-2-naphthyl beta-D-glucopyranoside；(2S,3R,4S,5S,6R)-2-(6-bromonaphthalen-2-yl)oxy-6-(hydroxymethyl)oxane-3,4,5-triol
• CAS: 15548-61-5
• 化学式: C₁₆H₁₇BrO₆
• 分子量: 385.211
• InChiKey: NLRXQZJJCPRATR-IBEHDNSVSA-N

物化性质

• 熔点：
  210-212 °C
• 沸点：
  609℃
• 密度：
  1.698
• 闪点：
  322℃

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  23
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  99.4
• 氢给体数：
  4
• 氢受体数：
  6

安全信息

• 安全说明：
  S24/25
• WGK Germany：
  3
• 海关编码：
  29400090
• 危险性防范说明：
  P261,P305+P351+P338
• 危险性描述：
  H315,H319,H335

反应信息

• 作为反应物：
  描述：

  6-溴-2-萘基-Β-D-吡喃葡糖苷 在 水 、 氧气 、 铂 作用下， 生成 6-溴-2-萘基BETA-D-吡喃葡萄糖苷酸
  参考文献：
  名称：

  Seligman et al., Journal Of Histochemistry and Cytochemistry, 1954, vol. 2, p. 209,211

  摘要：

  DOI：
• 作为产物：
  描述：

  (2R,3R,4S,5R,6R)-2-(acetoxymethyl)-6-((6-bromonaphthalen-2-yl)oxy)tetrahydro-2H-pyran-3,4,5-triyl triacetate 在 甲醇 、 sodium methylate 作用下， 生成 6-溴-2-萘基-Β-D-吡喃葡糖苷
  参考文献：
  名称：

  Cohen et al., Journal of Biological Chemistry, 1952, vol. 195, p. 607,608

  摘要：

  DOI：

文献信息

• Rapid and sensitive low pressure enzyme detection and measurement system
  申请人：BioControl Systems, Incorporated

  公开号：EP0335354A2

  公开（公告）日：1989-10-04

  There is disclosed a process and a device for detecting and measuring (1) the amount of enzyme present as a detecting system following a nucleic acid hybridization reaction or immunoreaction; (2) the level and activity of free enzyme in a biological sample; (3) the level of enzyme from contaminating microorganisms present in a sample; and (4) enzymes from pure culture isolates for microbial identification and antimicrobial susceptibility testing.

  本发明公开了一种工艺和装置，用于检测和测量：(1) 核酸杂交反应或免疫反应后作为检测系统存在的酶量；(2) 生物样品中游离酶的含量和活性；(3) 样品中污染微生物的酶含量；(4) 纯培养分离物中的酶，用于微生物鉴定和抗菌药物敏感性测试。
• Biological indicator
  申请人：American Sterilizer Company

  公开号：US10011843B2

  公开（公告）日：2018-07-03

  This invention relates to a biological indicator derived from a composition comprising: a host organism comprising a spore forming bacteria; a reporter gene for producing an indicator enzyme; a regulatory gene; and a vehicle for inserting the reporter gene and the regulatory gene in the host organism; the host organism bearing a transposable genetic element in its genome for inserting an insertion sequence in the regulatory gene; the insertion sequence comprising a transposase, a pair of terminal inverted repeat sequences, and at least one open reading frame for expressing the transposase. The vehicle may be taken up by the host organism. The insertion sequence may be inserted in the regulatory gene. The host organism may undergo sporulation to form the biological indicator. A process and an apparatus for using the biological indicator are disclosed.

  本发明涉及一种生物指示剂，其成分包括：由形成孢子的细菌组成的宿主生物；产生指示剂酶的报告基因；调控基因；以及将报告基因和调控基因插入宿主生物的载体；宿主生物的基因组中含有转座遗传因子，用于在调控基因中插入插入序列；插入序列包括转座酶、一对末端倒置重复序列和至少一个用于表达转座酶的开放阅读框。载体可被宿主生物吸收。插入序列可插入调控基因中。宿主生物可进行孢子繁殖以形成生物指示剂。本发明公开了一种使用生物指示剂的工艺和装置。
• Method for detecting Escherichia coli in a sample
  申请人：3M INNOVATIVE PROPERTIES COMPANY

  公开号：US10023898B2

  公开（公告）日：2018-07-17

  A method of detecting Listeria monocytogenes. The method comprises providing a culture device with a selective culture medium and a detection article comprising a first indicator system. The selective culture medium facilitates the growth of Listeria microorganisms. When a Listeria microorganism is detected in a sample contacted with the culture medium, the detection article is contacted with the culture medium to detect Listeria monocytogenes.

  一种检测李斯特菌的方法。该方法包括提供一个带有选择性培养基的培养装置和一个包含第一指示系统的检测物品。选择性培养基有利于李斯特菌微生物的生长。当在与培养基接触的样品中检测到李斯特菌微生物时，检测物品与培养基接触以检测单增李斯特菌。
• Method for detecting a Shigella or Cronobacter microorganism
  申请人：3M INNOVATIVE PROPERTIES COMPANY

  公开号：US10619181B2

  公开（公告）日：2020-04-14

  A method of detecting a Shigella or Cronobacter microorganism. The method comprises providing a culture device with a selective culture medium and a detection article comprising a first indicator system.

  一种检测志贺氏菌或克罗诺斯菌微生物的方法。该方法包括提供一个带有选择性培养基的培养装置和一个包含第一指示系统的检测物品。
• Method and medium for detecting vancomycin-resistant enterococcus
  申请人：Idexx Laboratories, Inc.

  公开号：US20020132285A1

  公开（公告）日：2002-09-19

  A microbe-specific medium for detection of vancomycin-resistant Enterococci in a test sample within 24 hours and preferably within 18 hours. The testing medium provides a selective growth medium for vancomycin-resistant Enterococci and includes specific nutrient indicators which only the target microbe can significantly metabolize and use for growth. The nutrient indicator contain a nutrient moiety and a detectable moiety linked together by a covalent bond. The nutrient indicators produce detectable signals only if the nutrient indicators are hydrolyzed by the Enterococci specific enzymes including &bgr;-glucosidase and pyrrolidonyl arylamidase.

  一种微生物特异性培养基，用于在 24 小时内，最好在 18 小时内检测检测样本中的耐万古霉素肠球菌。检测培养基为耐万古霉素肠球菌提供了一种选择性生长培养基，其中包括特定的营养指示剂，只有目标微生物才能显著代谢并利用这些指示剂生长。营养指示剂含有通过共价键连接在一起的营养分子和可检测分子。只有当营养指示剂被肠球菌特异性酶（包括&bgr;-葡萄糖苷酶和吡咯烷酰芳基酰胺酶）水解时，营养指示剂才会产生可检测信号。

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