Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR if necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on the left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. /Organic bases/Amines and related compounds/
Basic treatment: Establish a patent airway (oropharyngeal or nasopharyngeal airway, if needed). Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary ... . Monitor for shock and treat if necessary ... . Anticipate seizures and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with 0.9% saline (NS) during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 mL/kg up to 200 ml of water for dilution if the patent can swallow, has a strong gag reflex, and does not drool. Administer activated charcoal ... . Cover skin burns with dry sterile dressings after decontamination ... . /Organic bases/Amines and related compounds/
Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious, has severe pulmonary edema, or is in severe respiratory distress. Positive-pressure ventilation techniques with a bag-valve-mask device may be beneficial. Consider drug therapy for pulmonary edema ... . Monitor cardiac rhythm and treat arrhythmias as necessary ... . Start IV administration of D5W /SRP: "To keep open", minimal flow rate/. Use 0.9% saline (NS) or lactated Ringer's (LR) if signs of hypovolemia are present. For hypotension with signs of hypovolemia, administer fluid cautiously. If patient is unresponsive to these measures, vasopressors may be helpful. Watch for signs of fluid overload ... . Administer 1% solution methylene blue if patient is symptomatic with severe hypoxia, cyanosis, and cardiac compromise not responding to oxygen. ... . Treat seizures with diazepam or lorazepam ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Organic bases/Amines and related compounds/
/SURVEILLANCE/ Trona (sodium sesquicarbonate) is mined from an underground deposit in Wyoming and processed for use in glass, paper, detergent, and chemical applications. Trona dust is alkaline (pH 10.5) and can have an irritant effect on respiratory airways, mucous membranes, and the skin. A study population of 142 underground miners and 88 surface workers from one facility volunteered for an epidemiologic study. Their mean age was 37.6 yr and mean duration of employment was 10.0 yr. The percentage with chronic cough and phlegm was 23%; both symptoms were more common among smokers than nonsmokers. Thirty-three percent of the workers complained of dyspnea when hurrying on level ground or walking up a slight hill. Half of the workers complained of upper respiratory tract symptoms and eye irritation. Both smokers and exsmokers had significant declines of forced expiratory volume in 1 sec (FEV1.0) with age; exsmokers also had declines with work-years when compared to a nonsmoking comparison population. Nonsmokers with personal dust measurements had a significant decline of FEV1.0 related to respirable dust exposure. A shift study of 104 workers revealed a significant fall in FEV1.0 among nonsmokers and surface workers. Significance was approached in the high dust exposure group. An increase in the mean percent predicted forced vital capacity and FEV1.0 was shown for the 125 workers who had a 5-yr follow-up of pulmonary function. There was no correlation between the shift study decrements and the longitudinal 5-yr follow-up. Industrial hygiene dust sampling found elevated levels of total dust but lower respirable dust, with no detectable free silica.
/VETERINARY CASE REPORTS/ A case of feed misformulation resulted in the addition of sodium sesquicarbonate (SSC) into broiler chicken feed. SSC is a buffering agent used in the manufacture of high urea ruminant feeds that were also produced in this feed mill. Within 2 days of receipt of the tainted broiler feed on the farm, chickens were exhibiting polydypsia and wet droppings and had increased levels of mortality. The postmortem lesions were dehydration, fluid-filled intestines, swollen, pale kidneys, and visceral urate deposits. Histopathology of the kidneys revealed dilated tubules with a giant cell response, loss of tubular epithelium, and a few needlelike crystals. The mortality within 4 days of exposure in three severely affected houses reached 17%. An analysis of the feed revealed sodium levels ranging from 2.59% to 4.88%, with chloride levels of 0.24%-0.40%. Ten percent of the ration was thought to be SSC that contains 36% sodium. To determine if the presence of the SSC caused the problems observed, a controlled study was undertaken. One hundred fifty 3-wk-old broilers were evenly distributed into three floor pens. One group was fed a normal grower ration, a second group was fed a ration containing 5% SSC, and a third group received a ration with 10% SSC. Mortality, packed cell volumes (PCV), total serum proteins, and histopathology of the kidneys were determined. The 10% SSC group had a 6% mortality. Dehydration was evident by elevated PCV within 1 day of ingestion of either ration containing SSC. Microscopic lesions in the kidney were more severe in chickens ingesting SSC when compared with control groups.
Compounds with growth hormone releasing properties
申请人：——
公开号：US20030040483A1
公开（公告）日：2003-02-27
Compounds of peptide mimetic nature having the general formula I
1
wherein a and b are independently 1 or 2, R
1
and R
2
are independently H or C
1-6
alkyl, G and J are independently, inter alia, aromats, and D and E are independently several different groups are growth hormone secretagogous with improved bioavailability.
A new process is disclosed for the preparation of N-acyl-.alpha.-aromatic and N-acyl-.alpha.-heteroaromatic glycines by reaction of an .alpha.-ester or ether of an N-acylglycine ester or acid with an aromatic or heteroaromatic compound. Also disclosed are new intermediates for preparing N-acyl-.alpha.-aromatic and N-acyl-.alpha.-heteroaromatic glycines.
Process for recovering sodium carbonate from trona and other mixtures of
申请人：Allied Corporation
公开号：US04584077A1
公开（公告）日：1986-04-22
A process and a system for converting materials comprising sodium carbonate and sodium bicarbonate, such as dry-mined or subterranean deposits of trona, into a liquid comprising sodium carbonate substantially free of sodium bicarbonate. The process and the system incorporate the features of: (a) forming an aqueous solution comprising sodium carbonate and sodium bicarbonate; (b) removing a portion of said sodium bicarbonate from said solution to form a mother liquor comprising sodium carbonate and a reduced amount of sodium bicarbonate; (c) subjecting the mother liquor to electrodialytic water splitting by circulating the water liquor through an electrodialytic water splitter to produce a liquid reaction product comprising sodium carbonate substantially free of sodium bicarbonate; and (d) withdrawing the liquid reaction product comprising sodium carbonate substantially free of sodium bicarbonate from the electordialytic water splitter. The sodium carbonate solutions removed from the water splitter may be used as is, or subjected to further processing to produce a more concentrated final product. Two or three compartment electrodialytic water splitters can be used. The invention also details an effective method and system for isolating sodium carbonate by an electrodialysis process which eliminates the generation of CO.sub.2 gas in the water splitter.
Electrochemical system and process for stripping metallic coatings
申请人：General Electric Company
公开号：US06352636B1
公开（公告）日：2002-03-05
An electrochemical stripping process is described that strips at least one metallic coating from a substrate. Due to the electrochemical selectivity of the disclosed process, the parent alloy is minimally affected by the electrochemical stripping process. The process comprises providing an electrolyte; disposing the coated articles and at least one electrode in the electrolyte; applying a current between the electrode and the coated articles, and removing the at least one coating from the coated articles without modifying the parent alloy. The system for the electrochemical stripping process comprises an electrolyte; a direct current source; and plurality of electrodes from which a direct current may be directed to the article being stripped. The direct current source is capable of being connected to the coated articles and the plurality of electrodes. The system permits removal of the at least one coating from the parent alloy.
GENERALLY SPHERICAL BARIUM CARBONATE PARTICLES, AND METHOD FOR PRODUCING GENERALLY SPHERICAL BARIUM CARBONATE PARTICLES
申请人：Shimizu Yusuke
公开号：US20120045381A1
公开（公告）日：2012-02-23
The present invention has an object to provide a method for producing particulate barium carbonate having desired properties such as high purity, fineness, and has a spherical shape. The present invention relates to a method of producing substantially spherical barium carbonate, including (A) mixing, in an aqueous medium, a barium compound with at least one first ingredient selected from the group consisting of gluconic acid or salts thereof, gluconolactone, glucoheptonic acid or salts thereof, and glucoheptonolactone, to prepare a mixture; and (B) reacting the barium compound with carbon dioxide or a water-soluble carbonate in the mixture, to produce substantially spherical barium carbonate.
