2,3,5-tri-O-benzoyl-6-O-benzyl-β-D-galactofuranosyl trichloroacetimidate | 211676-39-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2,3,5-tri-O-benzoyl-6-O-benzyl-β-D-galactofuranosyl trichloroacetimidate
• 英文别名: Bz(-2)[Bz(-3)][Bz(-5)][Bn(-6)]Galf(b)-O-C(NH)CCl3；[(2S,3S,4R,5S)-4-benzoyloxy-2-[(1R)-1-benzoyloxy-2-phenylmethoxyethyl]-5-(2,2,2-trichloroethanimidoyl)oxyoxolan-3-yl] benzoate
• CAS: 211676-39-0
• 化学式: C₃₆H₃₀Cl₃NO₉
• 分子量: 726.995
• InChiKey: ZZNRWQRTWQOPIJ-BBQPZQQSSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.1
• 重原子数：
  49
• 可旋转键数：
  16
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  130
• 氢给体数：
  1
• 氢受体数：
  10

反应信息

• 作为反应物：
  描述：

  2,3,5-tri-O-benzoyl-6-O-benzyl-β-D-galactofuranosyl trichloroacetimidate 在 palladium on activated charcoal molecular sieve 、 三氟甲磺酸三甲基硅酯 、 氢气 、 sodium methylate 作用下， 以 甲醇 、 二氯甲烷 、 溶剂黄146 为溶剂， 反应 2.33h， 生成 methyl 6-O-(β-D-galactofuranosyl)β-D-galactofuranoside
  参考文献：
  名称：

  Synthesis of some galactofuranosyl disaccharides using a galactofuranosyl trichloroacetimidate as donor

  摘要：

  2,3,5-Tri-O-benzoyl-6-O-benzyl-beta-D-galactofuranosyl trichloroacetimidate has been prepared for the first time and utilised as glycosyl donor for the synthesis of several disaccharides containing the beta-linked galactofuranoside moiety. (C) 1998 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0008-6215(98)00062-7
• 作为产物：
  描述：

  methyl 6-O-benzyl-β-D-galactofuranoside 在 吡啶 、 硫酸 、 氢溴酸 、 乙酸酐 、 potassium carbonate 作用下， 以 二氯甲烷 、 溶剂黄146 为溶剂， 反应 11.0h， 生成 2,3,5-tri-O-benzoyl-6-O-benzyl-β-D-galactofuranosyl trichloroacetimidate
  参考文献：
  名称：

  Synthesis of some galactofuranosyl disaccharides using a galactofuranosyl trichloroacetimidate as donor

  摘要：

  2,3,5-Tri-O-benzoyl-6-O-benzyl-beta-D-galactofuranosyl trichloroacetimidate has been prepared for the first time and utilised as glycosyl donor for the synthesis of several disaccharides containing the beta-linked galactofuranoside moiety. (C) 1998 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0008-6215(98)00062-7

文献信息

• Synthesis of some galactofuranosyl disaccharides using a galactofuranosyl trichloroacetimidate as donor
  作者：Ambar Kumar Choudhury、Nirmolendu Roy

  DOI：10.1016/s0008-6215(98)00062-7

  日期：1998.3

  2,3,5-Tri-O-benzoyl-6-O-benzyl-beta-D-galactofuranosyl trichloroacetimidate has been prepared for the first time and utilised as glycosyl donor for the synthesis of several disaccharides containing the beta-linked galactofuranoside moiety. (C) 1998 Elsevier Science Ltd. All rights reserved.