Self-complementary hydrogen-bond interactions of guanosine: a hub for constructing supra-amphiphilic polymers with controlled molecular structure and aggregate morphology
作者:Qian Xiao、Fei Song、Wu-Cheng Nie、Xiu-Li Wang、Yu-Zhong Wang
DOI:10.1039/c8sm02172d
日期:——
A supra-amphiphilic polymer (SAP) with controlled molecular structures is constructed, in this work, via self-complementary hydrogen bonding of guanosine groups between a hydrophilic block, poly(N-isopropylacrylamide), and a hydrophobic block, poly(ε-caprolactone). By simply changing the mixing ratio of the guanosine-capped hydrophilic and hydrophobic blocks, a series of SAPs with tailored nanostructures
在这项工作中,通过亲水嵌段聚(N-异丙基丙烯酰胺)和疏水嵌段聚(ε-己内酯)之间鸟苷基团的自互补氢键结合,构建了具有受控分子结构的超两亲聚合物(SAP))。通过简单地改变鸟嘌呤封端的亲水性和疏水性嵌段的混合比例,可以构建一系列具有定制纳米结构的SAP,它们可以在溶液中进一步自组装成不同的纳米聚集体,包括球体,囊泡和大囊泡胶束。加热后,亲水性嵌段的热诱导相变诱导纳米颗粒融合和聚集,形成不规则颗粒,冷却后进一步转变为大的化合物囊泡。