p-phenoxyacetyl chloride

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: p-phenoxyacetyl chloride
• 英文别名: 2-[4-[Tris(4-tert-butylphenyl)methyl]phenoxy]acetyl chloride
• 化学式: C₃₉H₄₅ClO₂
• 分子量: 581.238
• InChiKey: DEDUHIIOSGMYNO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  12.5
• 重原子数：
  42
• 可旋转键数：
  10
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2-(2-(4-(9-(4-(2-(2-(dec-9-en-1-yloxy)ethoxy)ethoxy)phenyl)-1,10-phenanthrolin-2-yl)phenoxy)ethoxy)ethan-1-ol 、 p-phenoxyacetyl chloride 在 2,6-二甲基吡啶 作用下， 以 二氯甲烷 为溶剂， 反应 3.0h， 以85%的产率得到2-(2-(4-(9-(4-(2-(2-(dec-9-en-1-yloxy)ethoxy)ethoxy)phenyl)-1,10-phenanthrolin-2-yl)phenoxy)ethoxy)ethyl 2-(4-(tris(4-(tert-butyl)phenyl)methyl)phenoxy)acetate
  参考文献：
  名称：

  Xue, Zheng; Mayers, Michael F., Journal of the American Chemical Society, 2010, vol. 132, p. 3274 - 3276

  摘要：

  DOI：
• 作为产物：
  描述：

  1,1,1-三(4-叔丁基苯基)甲醇 在 盐酸 、 氢氧化钾 、 氯化亚砜 作用下， 反应 109.0h， 生成 p-phenoxyacetyl chloride
  参考文献：
  名称：

  New triarylmethyl derivatives: "blocking groups" for rotaxanes and polyrotaxanes

  摘要：

  Five triarylcarbinols (8, three new compounds) were synthesized. Using carbanion chemistry the triarylmethanes (13, five new compounds) made by formic acid reduction of 8 were converted to the omega,omega,omega-triarylalkanols (15,three new compounds) and thence to the chloro (17) and iodo (18) derivatives (five new compounds). Via carbocation chemistry p-(triarylmethyl)phenols (20,two new compounds) and aniline (21, new compound) were produced. Alkylation of 20 yielded alcohol (22), benzylic bromide (23), and carboxy (25) functionalized derivatives. The alcohol, halide, phenol, aniline, and carboxylic acid functionalized triarylmethane compounds are suitable end blocking groups for rotaxanes and polyrotaxanes.

  DOI：

  10.1021/jo00066a030

文献信息

• The Electrochemically-Driven Decomplexation/Recomplexation of Inclusion Adducts of Ferrocene Derivatives with an Electron-Accepting Receptor
  作者：Vincenzo Balzani、Jan Becher、Alberto Credi、Mogens B. Nielsen、Françisco M. Raymo、J. Fraser Stoddart、Anna Maria Talarico、Margherita Venturi

  DOI：10.1021/jo991467z

  日期：2000.4.1

  The tetracationic cyclophane, cyclobis(paraquat-4,4'-biphenylene), binds 1,1'-disubstituted ferrocene-based polyethers as a result of (i) [pi...pi] stacking between the pi-electron-deficient bipyridinium units and the pi-electron-rich cyclopentadienyl rings and (ii) [C-H ... O] hydrogen bonds between the alpha-bipyridinium hydrogen atoms and the polyether oxygen atoms. However, even the presence of a bulky tetraarylmethane group-which is too large to thread through the cavity of the cyclophane host-at the end of each of the two polyether substituents of the ferrocene-containing guest does not discourage adduct formation of the inclusion type. Thus, in these adducts, the ferrocene unit of the guest is located inside the cavity of the host with its two polyether chains protruding outward from the same side of the host. The alternative pseudorotaxane geometry is not observed in solutions of these 1:i adducts. The host-guest adducts display absorption bands in the visible spectral region, characteristic of charge-transfer interactions. In the case of one of these adducts, reversible decomplexation/recomplexation takes place upon electrochemical oxidation/reduction of the ferrocene-based unit or upon reduction/oxidation of the tetracationic cyclophane.
• New triarylmethyl derivatives: "blocking groups" for rotaxanes and polyrotaxanes
  作者：Harry W. Gibson、Sang Hun Lee、Paul T. Engen、Pierre Lecavalier、Jean Sze、Ya Xi Shen、Mukesh Bheda

  DOI：10.1021/jo00066a030

  日期：1993.7

  Five triarylcarbinols (8, three new compounds) were synthesized. Using carbanion chemistry the triarylmethanes (13, five new compounds) made by formic acid reduction of 8 were converted to the omega,omega,omega-triarylalkanols (15,three new compounds) and thence to the chloro (17) and iodo (18) derivatives (five new compounds). Via carbocation chemistry p-(triarylmethyl)phenols (20,two new compounds) and aniline (21, new compound) were produced. Alkylation of 20 yielded alcohol (22), benzylic bromide (23), and carboxy (25) functionalized derivatives. The alcohol, halide, phenol, aniline, and carboxylic acid functionalized triarylmethane compounds are suitable end blocking groups for rotaxanes and polyrotaxanes.
• Xue, Zheng; Mayers, Michael F., Journal of the American Chemical Society, 2010, vol. 132, p. 3274 - 3276
  作者：Xue, Zheng、Mayers, Michael F.

  DOI：——

  日期：——